PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

---

4JV0	Ring-Opening of the -OH-PdG Adduct in Ternary Complexes with the Sulfolobus solfataricus DNA polymerase Dpo4 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3'), ... 著者 Banerjee, S, Shanmugam, G, Stone, M.P. 登録日 2013-03-25 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4. Chem.Res.Toxicol., 26, 2013
4HEF	Structure of avibactam bound to Pseudomonas aeruginosa AmpC 分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, GLYCEROL 著者 Lahiri, S.D. 登録日 2012-10-03 公開日 2013-06-05 最終更新日 2020-09-16 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-Lactamases Antimicrob.Agents Chemother., 57, 2013
4HEW	Activity Enhancers of H64A Variant of Human Carbonic Anhydrase II Possess Multiple Binding Sites within and around the Enzyme Structure 分子名称: 2-METHYLIMIDAZOLE, Carbonic anhydrase 2, ZINC ION 著者 Aggarwal, M, McKenna, R. 登録日 2012-10-04 公開日 2013-10-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6984 Å) 主引用文献 Structural insight into activity enhancement and inhibition of H64A carbonic anhydrase II by imidazoles. IUCrJ, 1, 2014
4GVW	Three-dimensional structure of the de novo designed serine hydrolase 2bfq_3, Northeast Structural Genomics Consortium (NESG) Target OR248 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETIC ACID, De novo designed serine hydrolase, ... 著者 Kuzin, A, Lew, S, Seetharaman, J, Rajagopalan, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2012-08-31 公開日 2012-09-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.113 Å) 主引用文献 Northeast Structural Genomics Consortium Target OR248 To be Published
2QKV	Crystal Structure of the C645S Mutant of the 5th PDZ Domain of InaD 分子名称: Inactivation-no-after-potential D protein 著者 Ranganathan, R, Socolich, M. 登録日 2007-07-11 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Dynamic Scaffolding in a G Protein-Coupled Signaling System. Cell(Cambridge,Mass.), 131, 2007
4HEB	The Crystal structure of Maf protein of Bacillus subtilis 分子名称: Septum formation protein Maf, UNKNOWN ATOM OR ION 著者 Dong, A, Dombrovski, L, Brown, G, Flick, R, Tchigvintsev, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Iakounine, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) 登録日 2012-10-03 公開日 2012-10-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Biochemical and structural studies of conserved maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides. Chem.Biol., 20, 2013
2R3J	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor 分子名称: 3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2 著者 Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. 登録日 2007-08-29 公開日 2008-01-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
2QSP	Bovine Hemoglobin at pH 5.7 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Aranda IV, R, Richards, M.P, Phillips Jr, G.N. 登録日 2007-07-31 公開日 2008-09-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss. Proteins, 75, 2008
2QTA	E. coli Pyruvate dehydrogenase E1 component E401K mutant with thiamin diphosphate 分子名称: MAGNESIUM ION, Pyruvate dehydrogenase E1 component, THIAMINE DIPHOSPHATE 著者 Furey, W, Arjunan, P, Chandrasekhar, K. 登録日 2007-08-01 公開日 2007-08-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A Dynamic Loop at the Active Center of the Escherichia coli Pyruvate Dehydrogenase Complex E1 Component Modulates Substrate Utilization and Chemical Communication with the E2 Component J.Biol.Chem., 282, 2007
4HF0	Crystal Structure of Apo IscR 分子名称: HTH-type transcriptional regulator IscR, SULFATE ION 著者 Rajagopalan, S.R, Phillips, K.J. 登録日 2012-10-04 公開日 2013-05-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity. Nat.Struct.Mol.Biol., 20, 2013
4HG0	Crystal Structure of magnesium and cobalt efflux protein CorC, Northeast Structural Genomics Consortium (NESG) Target ER40 分子名称: ADENOSINE MONOPHOSPHATE, Magnesium and cobalt efflux protein CorC 著者 Kuzin, A, Neely, H, Seetharaman, J, Patel, P, Xiao, R, Ciccosanti, C, Cooper, B, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2012-10-05 公開日 2013-02-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.102 Å) 主引用文献 Northeast Structural Genomics Consortium Target ER40 To be Published
4H0C	Crystal structure of phospholipase/Carboxylesterase from Dyadobacter fermentans DSM 18053 分子名称: CITRIC ACID, GLYCEROL, Phospholipase/Carboxylesterase, ... 著者 Chang, C, Holowicki, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2012-09-07 公開日 2012-09-26 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal structure of phospholipase/Carboxylesterase from Dyadobacter fermentans DSM 18053 To be Published
4JMW	Crystal structure of Cytochrome C Peroxidase W191G-Gateless in complex with Phenol 分子名称: Cytochrome c peroxidase, PHENOL, PROTOPORPHYRIN IX CONTAINING FE 著者 Fischer, M, Fish, I. 登録日 2013-03-14 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Blind prediction of charged ligand binding affinities in a model binding site. J.Mol.Biol., 425, 2013
4JCA	Crystal Structure of the apo form of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1. Northeast Structural Genomics Consortium (NESG) Target OR273 分子名称: CITRIC ACID, RUBIDIUM ION, serine hydrolase 著者 Kuzin, A.P, Lew, S, Rajagopalan, S, Seetharaman, J, Tong, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2013-02-21 公開日 2013-03-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.411 Å) 主引用文献 Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
4JEM	Crystal structure of MilB complexed with cytidine 5'-monophosphate 分子名称: CMP/hydroxymethyl CMP hydrolase, CYTIDINE-5'-MONOPHOSPHATE 著者 Sikowitz, M.D, Cooper, L.E, Begley, T.P, Kaminski, P.A, Ealick, S.E. 登録日 2013-02-27 公開日 2013-09-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.553 Å) 主引用文献 Reversal of the substrate specificity of CMP N-glycosidase to dCMP. Biochemistry, 52, 2013
1QII	SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT F) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE 分子名称: ACETYLCHOLINESTERASE 著者 Kryger, G, Weik, M, Ravelli, R.B.G. 登録日 1999-06-14 公開日 2000-01-28 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Specific chemical and structural damage to proteins produced by synchrotron radiation. Proc.Natl.Acad.Sci.USA, 97, 2000
4JH0	Crystal structure of dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) (DPP-IV-WT) complex with bms-767778 AKA 2-(3-(aminomethyl)-4-(2,4- dichlorophenyl)-2-methyl-5-oxo-5,7-dihydro-6h-pyrrolo[3,4- b]pyridin-6-yl)-n,n-dimethylacetamide 分子名称: 2-[3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-N,N-dimethylacetamide, Dipeptidyl peptidase 4 著者 Klei, H.E. 登録日 2013-03-04 公開日 2013-09-04 最終更新日 2013-10-09 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Optimization of Activity, Selectivity, and Liability Profiles in 5-Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)-2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778). J.Med.Chem., 56, 2013
1QIH	SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT E) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE 分子名称: PROTEIN (ACETYLCHOLINESTERASE) 著者 Kryger, G, Weik, M, Ravelli, R.B.G. 登録日 1999-06-14 公開日 2000-01-28 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Specific chemical and structural damage to proteins produced by synchrotron radiation. Proc.Natl.Acad.Sci.USA, 97, 2000
4JL8	A various kinds of ADP conformations in the Adenylate kinase active site 分子名称: ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase 著者 Cho, Y.-J, Kern, D. 登録日 2013-03-12 公開日 2014-06-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 The energy landscape of adenylate kinase during catalysis. Nat.Struct.Mol.Biol., 22, 2015
4JLD	Crystal Structures of adenylate kinase with 2 ADP's 分子名称: ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase 著者 Cho, Y.-J, Kern, D. 登録日 2013-03-12 公開日 2014-06-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.552 Å) 主引用文献 The energy landscape of adenylate kinase during catalysis. Nat.Struct.Mol.Biol., 22, 2015
4JLL	Crystal Structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1 covalently bound with FP-alkyne, Northeast Structural Genomics Consortium (NESG) Target OR273 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Tong, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2013-03-12 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
4JMB	Crystal structure of Cytochrome C Peroxidase W191G-Gateless in complex with 5,6,7,8-tetrahydrothieno[2,3-b]quinolin-4-amine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5,6,7,8-tetrahydrothieno[2,3-b]quinolin-4-amine, Cytochrome c peroxidase, ... 著者 Barelier, S, Fischer, M. 登録日 2013-03-13 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Docking to a water-filled model binding site in Cytochrome c Peroxidase To be published
4JMZ	Crystal structure of Cytochrome C Peroxidase W191G-Gateless in complex with N-methyl-1H-benzimidazol-2-amine 分子名称: Cytochrome c peroxidase, N-methyl-1H-benzimidazol-2-amine, PROTOPORPHYRIN IX CONTAINING FE 著者 Barelier, S, Fischer, M. 登録日 2013-03-14 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Roles for ordered and bulk solvent in ligand recognition and docking in two related cavities. Plos One, 8, 2013
4JO9	Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex 1:2 stoichiometry 分子名称: Nucleoporin p54, Nucleoporin p58/p45 著者 Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. 登録日 2013-03-18 公開日 2014-09-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.499 Å) 主引用文献 Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
4JPT	Crystal structure of Cytochrome C Peroxidase W191G-Gateless in complex with quinazoline-2,4-diamine 分子名称: Cytochrome c peroxidase, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Boyce, S.E, Fischer, M, Fish, I. 登録日 2013-03-19 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Blind prediction of charged ligand binding affinities in a model binding site. J.Mol.Biol., 425, 2013

<769770771772773774775776777778779780781782783784>