2QTA

E. coli Pyruvate dehydrogenase E1 component E401K mutant with thiamin diphosphate

Summary for 2QTA

Entry DOI	10.2210/pdb2qta/pdb
Related	2G25 2G28 2IEA 2QTC
Descriptor	Pyruvate dehydrogenase E1 component, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	pyruvate dehydrogenase, thiamin diphosphate, glycolysis, magnesium, metal-binding, oxidoreductase, thiamine pyrophosphate
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	200213.71
Authors	Furey, W.,Arjunan, P.,Chandrasekhar, K. (deposition date: 2007-08-01, release date: 2007-08-14, Last modification date: 2023-08-30)
Primary citation	Kale, S.,Arjunan, P.,Furey, W.,Jordan, F. A Dynamic Loop at the Active Center of the Escherichia coli Pyruvate Dehydrogenase Complex E1 Component Modulates Substrate Utilization and Chemical Communication with the E2 Component J.Biol.Chem., 282:28106-28116, 2007 Cited by PubMed: 17635929 DOI: 10.1074/jbc.M704326200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation