4HEF
Structure of avibactam bound to Pseudomonas aeruginosa AmpC
Summary for 4HEF
| Entry DOI | 10.2210/pdb4hef/pdb |
| Descriptor | Beta-lactamase, GLYCEROL, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, ... (4 entities in total) |
| Functional Keywords | b-lactamase, hydrolase, periplasmic protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Pseudomonas aeruginosa |
| Total number of polymer chains | 1 |
| Total formula weight | 39993.09 |
| Authors | Lahiri, S.D. (deposition date: 2012-10-03, release date: 2013-06-05, Last modification date: 2020-09-16) |
| Primary citation | Lahiri, S.D.,Mangani, S.,Durand-Reville, T.,Benvenuti, M.,De Luca, F.,Sanyal, G.,Docquier, J.D. Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-Lactamases Antimicrob.Agents Chemother., 57:2496-2505, 2013 Cited by PubMed: 23439634DOI: 10.1128/AAC.02247-12 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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