8YJF
 
 | | Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and an H2A-H2B dimer | | 分子名称: | DNA replication licensing factor MCM2, FACT complex subunit SPT16, Histone H2A type 1-D, ... | | 著者 | Gan, S.L, Yang, W.S, Xu, R.M. | | 登録日 | 2024-03-01 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | | 主引用文献 | Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2.
Sci China Life Sci, 67, 2024
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8W0U
 | | Human LCAD complexed with Acetoacetyl Coenzyme A | | 分子名称: | ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, ... | | 著者 | Xia, C, Kim, J.J.P. | | 登録日 | 2024-02-14 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.
Sci Rep, 14, 2024
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8VK3
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8USX
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8VJJ
 | | Structure of mouse RyR1 (EGTA-only dataset) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ... | | 著者 | Weninger, G, Marks, A.R. | | 登録日 | 2024-01-07 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | | 主引用文献 | Structural insights into the regulation of RyR1 by S100A1.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8V6K
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8VK4
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8V6O
 | | Inactivated-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-aminoethyl diphenylborinate, SODIUM ION, ... | | 著者 | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | | 登録日 | 2023-12-01 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Sci Adv, 10, 2024
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8WMH
 | | Structure of CbCas9 bound to 6-nucleotide complementary DNA substrate | | 分子名称: | NTS, TS, deadCbCas9, ... | | 著者 | Zhang, S, Lin, S, Liu, J.J.G. | | 登録日 | 2023-10-03 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity.
Nature, 630, 2024
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4CP3
 | | The structure of BCL6 BTB (POZ) domain in complex with the ansamycin antibiotic rifabutin. | | 分子名称: | B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN | | 著者 | Evans, S.E, Fairall, L, Goult, B.T, Jamieson, A.G, Ferrigno, P.K, Ford, R, Wagner, S.D, Schwabe, J.W.R. | | 登録日 | 2014-01-31 | | 公開日 | 2014-03-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014
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3IPB
 | | Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (11 carbon linker). | | 分子名称: | 2,2'-{undecane-1,11-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid, Transthyretin | | 著者 | Kolstoe, S.E, Wood, S.P, Pepys, M.B. | | 登録日 | 2009-08-17 | | 公開日 | 2010-11-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3IPE
 | | Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (7 carbon linker). | | 分子名称: | 2,2'-{heptane-1,7-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid, Transthyretin | | 著者 | Kolstoe, S.E, Wood, S.P, Pepys, M.B. | | 登録日 | 2009-08-17 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4M3I
 | | X-ray crystal structure of the ruthenium complex [Ru(TAP)2(dppz-{Me2})]2+ bound to d(CCGGTACCGG) | | 分子名称: | (11,12-dimethyldipyrido[3,2-a:2',3'-c]phenazine-kappa~2~N~4~,N~5~)[bis(pyrazino[2,3-f]quinoxaline-kappa~2~N~1~,N~10~)]ruthenium(2+), BARIUM ION, Synthetic DNA CCGGTACCGG | | 著者 | Niyazi, H, Teixeira, S, Mitchell, E, Forsyth, T, Cardin, C. | | 登録日 | 2013-08-06 | | 公開日 | 2014-09-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-ray crystal structure of the ruthenium complex [Ru(TAP)2(dppz-{Me2})]2+ bound to d(CCGGTACCGG)
To be Published
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3E2S
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4Y1M
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7V62
 | | Crystal structure of human OSBP ORD in complex with cholesterol | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHOLESTEROL, CITRIC ACID, ... | | 著者 | Kobayashi, J, Kato, R. | | 登録日 | 2021-08-19 | | 公開日 | 2022-06-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Ligand Recognition by the Lipid Transfer Domain of Human OSBP Is Important for Enterovirus Replication.
Acs Infect Dis., 8, 2022
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3EQ6
 | | Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a ternary complex with products | | 分子名称: | ADENOSINE MONOPHOSPHATE, Acyl-coenzyme A synthetase ACSM2A, Butyryl Coenzyme A | | 著者 | Pilka, E.S, Kochan, G, Yue, W.W, Bhatia, C, Von delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2008-09-30 | | 公開日 | 2008-10-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
J.Mol.Biol., 388, 2009
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3WB5
 | | Crystal Structure of beta secetase in complex with (6S)-2-amino-3,6-dimethyl-6-[(1R,2R)-2-phenylcyclopropyl]-3,4,5,6-tetrahydropyrimidin-4-one | | 分子名称: | (6S)-2-amino-3,6-dimethyl-6-[(1R,2R)-2-phenylcyclopropyl]-5,6-dihydropyrimidin-4(3H)-one, Beta-secretase 1, DIMETHYL SULFOXIDE, ... | | 著者 | Yonezawa, S, Fujiwara, K, Yamamoto, T, Hattori, K, Yamakawa, H, Muto, C, Hosono, M, Tanaka, Y, Nakano, T, Takemoto, H, Arisawa, M, Shuto, S. | | 登録日 | 2013-05-13 | | 公開日 | 2013-10-02 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Conformational restriction approach to beta-secretase (BACE1) inhibitors III: Effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations
Bioorg.Med.Chem., 21, 2013
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4ESA
 | | X-ray structure of carbonmonoxy hemoglobin of Eleginops maclovinus | | 分子名称: | CARBON MONOXIDE, GLYCEROL, Hemoglobin alpha chain, ... | | 著者 | Merlino, A, Vitagliano, L, Mazzarella, L, Vergara, A. | | 登録日 | 2012-04-23 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus.
Mol Biosyst, 8, 2012
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3WDJ
 | | Crystal structure of Pullulanase complexed with maltotetraose from Anoxybacillus sp. LM18-11 | | 分子名称: | CALCIUM ION, Type I pullulanase, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Xu, J, Ren, F, Huang, C.H, Zheng, Y, Zhen, J, Ko, T.P, Chen, C.C, Chan, H.C, Guo, R.T, Ma, Y, Song, H. | | 登録日 | 2013-06-18 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Cloning, Expression, Functional and Structural Studies of Pullulanase from Anoxybacillus sp. LM18-11
To be Published
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4XUR
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7TFB
 | | P. polymyxa GS(14)-Q-GlnR peptide | | 分子名称: | GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ... | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.28 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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7TF9
 | | L. monocytogenes GS(14)-Q-GlnR peptide | | 分子名称: | C-tail peptide of Glutamine synthetase repressor, GLUTAMINE, Glutamine synthetase, ... | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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7TFC
 | | B. subtilis GS(14)-Q-GlnR peptide | | 分子名称: | GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ... | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (1.96 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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6UT8
 | | Refined half-complex from tetradecameric assembly of Thermococcus gammatolerans McrB AAA+ hexamers with bound McrC | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase subunit of restriction endonuclease, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Niu, Y, Suzuki, H, Hosford, C.J, Chappie, J.S, Walz, T. | | 登録日 | 2019-10-29 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes.
Nat Commun, 11, 2020
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