7V62

Crystal structure of human OSBP ORD in complex with cholesterol

Summary for 7V62

Entry DOI	10.2210/pdb7v62/pdb
Descriptor	Oxysterol-binding protein 1, CHOLESTEROL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (6 entities in total)
Functional Keywords	lipid binding protein, lipid transport protein, oxysterol binding protein, oxysterol binding protein-related domain, lipid transport
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	190641.56
Authors	Kobayashi, J.,Kato, R. (deposition date: 2021-08-19, release date: 2022-06-08, Last modification date: 2023-11-29)
Primary citation	Kobayashi, J.,Arita, M.,Sakai, S.,Kojima, H.,Senda, M.,Senda, T.,Hanada, K.,Kato, R. Ligand Recognition by the Lipid Transfer Domain of Human OSBP Is Important for Enterovirus Replication. Acs Infect Dis., 8:1161-1170, 2022 Cited by PubMed: 35613096 DOI: 10.1021/acsinfecdis.2c00108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.25 Å)

Structure validation