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7V62

Crystal structure of human OSBP ORD in complex with cholesterol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Oxysterol-binding protein 1polymer40446916.24UniProt (P22059)
Pfam (PF01237)
Homo sapiens (Human)
2E, J, M, Q
(A, B, C, D)
CHOLESTEROLnon-polymer386.74Chemie (CLR)
3F, G, K, N, O...
(A, B, C, D)
2,3-DIHYDROXY-1,4-DITHIOBUTANEnon-polymer154.36Chemie (DTT)
4H
(A)
CITRIC ACIDnon-polymer192.11Chemie (CIT)
5I, L, P, S
(A, C, D)
DIMETHYL SULFOXIDEnon-polymer78.14Chemie (DMS)
6T, U, V, W
(A, B, C, D)
waterwater18.010Chemie (HOH)
Sequence modifications
A, B, C, D: 406 - 807 (UniProt: P22059)
PDBExternal DatabaseDetails
Gly 404-expression tag
Pro 405-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight187664.8
Non-Polymers*Number of molecules15
Total formula weight2976.8
All*Total formula weight190641.6
*Water molecules are not included.

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PDB entries from 2025-07-23

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