PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

---

8PJV	Crystal structure of the computationally designed SAKe6DR protein 分子名称: SAKe6DR 著者 Wouters, S.M.L. 登録日 2023-06-23 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Computational design of the SAKe scaffold proteins To Be Published
6XX5	Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin 分子名称: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A. 登録日 2020-01-26 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020
6XKP	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-270 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV07-270 Heavy Chain, CV07-270 Light Chain, ... 著者 Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. 登録日 2020-06-26 公開日 2020-10-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model. Cell, 183, 2020
8PT8	JNK1 covalently bound to RU135 cyclohexenone based inhibitor 分子名称: GLYCEROL, Mitogen-activated protein kinase 8, methyl (1R,3R)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methylcarbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylate 著者 Sok, P, Poti, A, Remenyi, A. 登録日 2023-07-13 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Tunable c-Jun N-terminal kinase (JNK) inhibitors that target a specific cysteine by a reversible covalent bond To Be Published
7O85	Anthrax toxin prepore in complex with the neutralizing Fab cAb29 分子名称: CALCIUM ION, Fab, Protective antigen PA-63 著者 Hoelzgen, F, Zalk, R, Alcalay, R, Cohen-Schwartz, S, Garau, G, Shahar, A, Mazor, O, Frank, G.A. 登録日 2021-04-14 公開日 2021-04-28 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Neutralization of the anthrax toxin by antibody-mediated stapling of its membrane-penetrating loop. Acta Crystallogr D Struct Biol, 77, 2021
8PSR	ERK2 covalently bound to SynthRevD-12-opt artificial peptide 分子名称: GLYCEROL, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Sok, P, Poti, A, Gogl, G, Remenyi, A. 登録日 2023-07-13 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Targeting a key protein-protein interaction surface on mitogen-activated protein kinases by a Michael acceptor-based cyclic warhead scaffold To Be Published
8PJY	Crystal structure of the computationally designed SAKe6EEref protein 分子名称: SAKe6EEref 著者 Wouters, S.M.L. 登録日 2023-06-23 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Computational design of the SAKe scaffold proteins To Be Published
8PMZ	HEV gt3 P domain in complex with glycan-insensitive nAb p61.15 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pro-secreted protein ORF2, scFv_p61.15 著者 Ssebyatika, G, Krey, T. 登録日 2023-06-29 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.912 Å) 主引用文献 A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
8PIE	Crystal structure of the human nucleoside diphosphate kinase B domain in complex with the product AT-8500 formed by catalysis of compound AT-9010 分子名称: GLYCEROL, Nucleoside diphosphate kinase B, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate 著者 Feracci, M, Chazot, A, Ferron, F, Alvarez, K, Canard, B. 登録日 2023-06-21 公開日 2024-07-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The activation chain of the broad-spectrum antiviral bemnifosbuvir at atomic resolution Plos Biol., 2024
8PK1	Cas1-Cas2 CRISPR integrase bound to prespacer DNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system 分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, Chains: G,J, ... 著者 Sasnauskas, G, Gaizauskaite, U, Tamulaitiene, G. 登録日 2023-06-23 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 Structural basis for spacer acquisition in a type II-A CRISPR-Cas system To Be Published
8PIP	DNA triplex structure with Polypyridyl Ruthenium Complexes 分子名称: CHLORIDE ION, DNA (31-MER), Delta-Ru(phen)2(dppz) complex, ... 著者 Abdullrahman, A, Cardin, C.J, Hall, J.P. 登録日 2023-06-22 公開日 2024-07-10 最終更新日 2024-07-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 DNA triplex structure with bound ruthenium polypyridyl complexes To Be Published
8PJR	Crystal structure of the SAKe6AC-LB protein 分子名称: SAKe6AC-LB 著者 Wouters, S.M.L. 登録日 2023-06-23 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Computational design of the SAKe scaffold protein To Be Published
8PMY	HEV gt3 P domain in complex with glycan-insensitive nAb p60.15 分子名称: Capsid protein, ZINC ION, scFv_p60.15 著者 Ssebyatika, G, Krey, T. 登録日 2023-06-29 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.406 Å) 主引用文献 A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
8PNH	Chorismate mutase 分子名称: 3-PHENYLPYRUVIC ACID, 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, Bifunctional cyclohexadienyl dehydratase/chorismate mutase from Janthinobacterium sp. HH01, ... 著者 Khatanbaatar, T, Cordara, G, Krengel, U. 登録日 2023-06-30 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Chorismate mutase To Be Published
8PJX	Crystal structure of the computationally designed SAKe6FR protein 分子名称: CALCIUM ION, SAKe6FR 著者 Wouters, S.M.L. 登録日 2023-06-23 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Computational design of the SAKe scaffold proteins To Be Published
8PJT	Crystal structure of the computationally designed SAKe6DEref protein 分子名称: SAKe6DEref 著者 Wouters, S.M.L. 登録日 2023-06-23 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Computational design of the SAKe scaffold proteins To Be Published
4XLF	Tailspike protein double mutant D339N/E372A of E. coli bacteriophage HK620 in complex with pentasaccharide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ... 著者 Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S. 登録日 2015-01-13 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein. to be published
8PWE	Crystal structure of VDR complex with Novel Des-C-Ring and Aromatic-D-Ring analog 3a 分子名称: (1~{R},3~{S},5~{Z})-4-methylidene-5-[(~{E})-3-[3-(6-methyl-6-oxidanyl-hept-3-ynyl)phenyl]pent-2-enylidene]cyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 2, ... 著者 Rochel, N. 登録日 2023-07-20 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Novel Des-C-Ring and Aromatic-D-Ring analogs Acting as Potent Agonists of the Vitamin D Receptor (VDR) To Be Published
8PJS	Crystal structure of the computationally designed SAKe6CEref protein 分子名称: SAKeCEref 著者 Wouters, S.M.L. 登録日 2023-06-23 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Computational design of the SAKe scaffold proteins To Be Published
6XC2	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 heavy chain, CC12.1 light chain, ... 著者 Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. 登録日 2020-06-08 公開日 2020-07-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.112 Å) 主引用文献 Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
8PJ2	Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. 登録日 2023-06-22 公開日 2024-08-14 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
8PJ6	Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3 (off-pathway) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. 登録日 2023-06-22 公開日 2024-08-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
8R8O	Hallucinated de novo TIM barrel with three helical extensions - HalluTIM3-1 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Beck, J, Shanmugaratnam, S, Hocker, B. 登録日 2023-11-29 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Diversifying de novo TIM barrels by hallucination. Protein Sci., 33, 2024
8QLV	Crystal structure of the pneumococcal Substrate-binding protein AliB in complex with Peptide 4 分子名称: Oligopeptide-binding protein AliB, VAL-MET-VAL-LYS-GLY-PRO-GLY-PRO-GLY-ARG 著者 Alcorlo, M, Abdullah, M.R, Hammerschmidt, S, Hermoso, J. 登録日 2023-09-20 公開日 2024-05-22 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Molecular and structural basis of oligopeptide recognition by the Ami transporter system in pneumococci. Plos Pathog., 20, 2024
8QAH	X-ray crystal structure of a de novo designed single-chain parallel coiled-coil alpha-helical barrel with 8 inner helices, sc-CC-8-58 分子名称: sc-CC-8-58 著者 Petrenas, R, Albanese, K.I, Woolfson, D.N. 登録日 2023-08-22 公開日 2024-07-03 最終更新日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Rationally seeded computational protein design of ɑ-helical barrels. Nat.Chem.Biol., 20, 2024

<764765766767768769770771772773774775776777778779>