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5A7X
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negative stain EM of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195, ...
著者Scharf, L, Wang, H, Gao, H, Chen, S, McDowall, A, Bjorkman, P.
登録日2015-07-10
公開日2015-08-05
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Broadly Neutralizing Antibody 8Anc195 Recognizes Closed and Open States of HIV-1 Env.
Cell(Cambridge,Mass.), 162, 2015
4XGY
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GFP based antibody (fluorobody)
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Green fluorescent protein, mAb LCDR3
著者Shi, N, Chen, Y.G, Wang, S.H.
登録日2015-01-03
公開日2015-07-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.494 Å)
主引用文献The structure of a GFP-based antibody (fluorobody) to TLH, a toxin from Vibrio parahaemolyticus.
Acta Crystallogr.,Sect.F, 71, 2015
5XRQ
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Crystal structure of human monoclonal antibody H3v-47
分子名称: Fab H3v-47 heavy chain, Fab H3v-47 light chain
著者Zhang, H, Willson, I.A.
登録日2017-06-09
公開日2018-07-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Nat Commun, 9, 2018
1A3L
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BU of 1a3l by Molmil
CATALYSIS OF A DISFAVORED REACTION: AN ANTIBODY EXO DIELS-ALDERASE-TSA-INHIBITOR COMPLEX AT 1.95 A RESOLUTION
分子名称: 1-CARBOXY-1'-[(DIMETHYLAMINO)-CARBONYL]FERROCENE, IMMUNOGLOBULIN FAB 13G5 (HEAVY CHAIN), IMMUNOGLOBULIN FAB 13G5 (LIGHT CHAIN)
著者Heine, A, Wilson, I.A.
登録日1998-01-22
公開日1999-02-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution.
Science, 279, 1998
4IJ3
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Oxidoreductase Fragment of Human QSOX1 in Complex with a FAB Fragment from an Anti- Human QSOX1 Antibody
分子名称: Heavy chain of FAB fragment, Light chain of FAB fragment, PHOSPHATE ION, ...
著者Fass, D, Grossman, I.
登録日2012-12-21
公開日2013-11-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An Inhibitory Antibody Blocks the First Step in the Dithiol/Disulfide Relay Mechanism of the Enzyme QSOX1.
J.Mol.Biol., 425, 2013
6XPY
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BU of 6xpy by Molmil
Human antibody S1V2-58 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
分子名称: Fab heavy chain, Fab light chain, Hemagglutinin, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2020-07-09
公開日2021-05-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.603 Å)
主引用文献A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
7R6W
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BU of 7r6w by Molmil
SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2X35 Fab and S309 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Snell, G, Czudnochowski, N, Hernandez, P, Nix, J.C, Croll, T.I, Corti, D, Cameroni, E, Pinto, D, Beltramello, M.
登録日2021-06-23
公開日2021-07-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
3L95
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Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus notch homolog protein 1, ...
著者Hymowitz, S.G, de Leon, G.P.
登録日2010-01-04
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Therapeutic antibody targeting of individual Notch receptors.
Nature, 464, 2010
6VPX
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BU of 6vpx by Molmil
Nanodisc of full-length HIV-1 Envelope glycoprotein clone AMC011 in complex with one PGT151 Fab and three 10E8 Fabs
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rantalainen, K, Ward, A.B.W.
登録日2020-02-04
公開日2020-04-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies.
Cell Rep, 31, 2020
4JY4
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Crystal structure of human Fab PGT121, a broadly reactive and potent HIV-1 neutralizing antibody
分子名称: GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PGT121 heavy chain, ...
著者Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A.
登録日2013-03-29
公開日2013-05-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Plos Pathog., 9, 2013
6X96
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BU of 6x96 by Molmil
Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 10A fragment antigen binding variable domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ...
著者Ozorowski, G, Cottrell, C.A, Ward, A.B.
登録日2020-06-02
公開日2021-12-08
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published
6X97
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Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11A fragment antigen binding variable domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ...
著者Ozorowski, G, Cottrell, C.A, Ward, A.B.
登録日2020-06-02
公開日2021-12-08
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published
4JY6
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BU of 4jy6 by Molmil
Crystal structure of human Fab PGT123, a broadly reactive and potent HIV-1 neutralizing antibody
分子名称: GLYCEROL, PGT123 heavy chain, PGT123 light chain, ...
著者Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A.
登録日2013-03-29
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans.
Plos Pathog., 9, 2013
3K3Q
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BU of 3k3q by Molmil
Crystal Structure of a Llama Antibody complexed with the C. Botulinum Neurotoxin Serotype A Catalytic Domain
分子名称: Botulinum neurotoxin type A, ZINC ION, llama Aa1 VHH domain
著者Thompson, A.A, Dong, J, Marks, J.D, Stevens, R.C.
登録日2009-10-04
公開日2010-02-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic alpha-Exosite Binding Region.
J.Mol.Biol., 397, 2010
6RCO
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BU of 6rco by Molmil
PfRH5-binding monoclonal antibody R5.004
分子名称: ACETATE ION, GLYCEROL, R5.004 heavy chain, ...
著者Alanine, D.G.W, Draper, S.J, Higgins, M.K.
登録日2019-04-11
公開日2019-06-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6OZ3
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BU of 6oz3 by Molmil
Crystal structure of broadly neutralizing antibody N49P9.1 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N49P9.1 antibody Fab heavy chain, N49P9.1 antibody Fab light chain, ...
著者Tolbert, W.D, Pazgier, M.
登録日2019-05-15
公開日2020-08-19
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Crystal structure of broadly neutralizing antibody N49P9.1 Fab in complex with HIV-1 Clade A/E strain 93TH)57 gp120 core
To Be Published
8DPM
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BU of 8dpm by Molmil
Structure of EBOV GP lacking the mucin-like domain with 9.20.1A2 Fab and 6D6 scFv bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 6D6 scFv, Antibody 9.20.1A2 Fab heavy chain, ...
著者Yu, X, Saphire, E.O.
登録日2022-07-15
公開日2023-07-19
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus.
Cell Rep, 42, 2023
8PWW
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BU of 8pww by Molmil
PfRH5 bound to monoclonal antibody MAD8-151
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Farrell, B, Higgins, M.K.
登録日2023-07-21
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.945 Å)
主引用文献PfRH5 bound to monoclonal antibody MAD8-151
To Be Published
8PWU
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BU of 8pwu by Molmil
PfRH5 bound to monoclonal antibody MAD10-255
分子名称: Reticulocyte-binding protein homolog 5, monoclonal antibody MAD10-255
著者Farrell, B, Higgins, M.K.
登録日2023-07-21
公開日2024-06-05
実験手法X-RAY DIFFRACTION (3.148 Å)
主引用文献PfRH5 bound to monoclonal antibody MAD10-255
To Be Published
8PWV
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BU of 8pwv by Molmil
PfRH5 bound to monoclonal antibody MAD8-502
分子名称: Reticulocyte-binding protein homolog 5, monoclonal antibody MAD8-502
著者Farrell, B, Higgins, M.K.
登録日2023-07-21
公開日2024-06-05
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献PfRH5 bound to monoclonal antibody MAD8-502
To Be Published
8PWX
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BU of 8pwx by Molmil
PfRH5 bound to monoclonal antibody R5.008
分子名称: GLYCEROL, Reticulocyte-binding protein homolog 5, scFv fragment for antibody R5.008
著者Farrell, B, Higgins, M.K.
登録日2023-07-21
公開日2024-06-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献PfRH5 bound to monoclonal antibody R5.008
To Be Published
1BAF
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BU of 1baf by Molmil
2.9 ANGSTROMS RESOLUTION STRUCTURE OF AN ANTI-DINITROPHENYL-SPIN-LABEL MONOCLONAL ANTIBODY FAB FRAGMENT WITH BOUND HAPTEN
分子名称: IGG1-KAPPA AN02 FAB (HEAVY CHAIN), IGG1-KAPPA AN02 FAB (LIGHT CHAIN), N-(2-AMINO-ETHYL)-4,6-DINITRO-N'-(2,2,6,6-TETRAMETHYL-1-OXY-PIPERIDIN-4-YL)-BENZENE-1,3-DIAMINE
著者Leahy, D.J, Brunger, A.T, Fox, R.O, Hynes, T.R.
登録日1992-01-16
公開日1994-01-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献2.9 A resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten.
J.Mol.Biol., 221, 1991
8BS8
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Bovine naive ultralong antibody AbD08 collected at 100K
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Heavy chain, Light chain
著者Clarke, J.D, Douangamath, A, Mikolajek, H, Stuart, D.I, Owens, R.J.
登録日2022-11-24
公開日2023-05-24
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献The impact of exchanging the light and heavy chains on the structures of bovine ultralong antibodies.
Acta Crystallogr.,Sect.F, 80, 2024
3MBX
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BU of 3mbx by Molmil
Crystal structure of chimeric antibody X836
分子名称: PHOSPHATE ION, SODIUM ION, X836 HEAVY CHAIN, ...
著者Teplyakov, A, Obmolova, G, Gilliland, G.L.
登録日2010-03-26
公開日2010-06-30
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献On the domain pairing in chimeric antibodies.
Mol.Immunol., 47, 2010
4JY5
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Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody
分子名称: GLYCEROL, PGT122 heavy chain, PGT122 light chain
著者Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A.
登録日2013-03-29
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Plos Pathog., 9, 2013

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件を2024-11-06に公開中

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