PDB: 5470 件ウェブページステータス検索Chemie searchBIRD

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3ODS	Crystal structure of the K185A mutant of the N-terminal domain of human Symplekin 分子名称: 1,2-ETHANEDIOL, Symplekin 著者 Tong, L, Xiang, K. 登録日 2010-08-11 公開日 2010-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature, 467, 2010
1U3Z	Crystal structure of MLAC mutant of dimerisation domain of NF-kB p50 transcription factor 分子名称: Nuclear factor NF-kappa-B p105 subunit 著者 Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. 登録日 2004-07-23 公開日 2004-08-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding Structure, 12, 2004
3O51	Crystal structure of anthranilamide 10 bound to AuroraA 分子名称: N-[4-({3-[5-fluoro-2-(methylideneamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-2-(phenylamino)benzamide, cDNA FLJ58295, highly similar to Serine/threonine-protein kinase 6 著者 Huang, X. 登録日 2010-07-27 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor. J.Med.Chem., 53, 2010
1U2V	Crystal structure of Arp2/3 complex with bound ADP and calcium 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-Related Protein 2, Actin-Related Protein 3, ... 著者 Nolen, B.J, Littlefield, R.S, Pollard, T.D. 登録日 2004-07-20 公開日 2004-11-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP Proc.Natl.Acad.Sci.Usa, 101, 2004
1U7B	Crystal structure of hPCNA bound to residues 331-350 of the flap endonuclease-1 (FEN1) 分子名称: Proliferating cell nuclear antigen, SRQGSTQGRLDDFFKVTGSL peptide of Flap endonuclease-1 著者 Bruning, J.B, Shamoo, Y. 登録日 2004-08-03 公開日 2004-12-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1. Structure, 12, 2004
3RQG	Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD4 分子名称: Paxillin LD4 peptide, Programmed cell death protein 10 著者 Li, X, Zhang, R, Boggon, T.J. 登録日 2011-04-28 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3). J.Biol.Chem., 286, 2011
3RI4	Ets1 cooperative binding to widely separated sites on promoter DNA 分子名称: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA 著者 Babayeva, N.D, Mino, K, Tahirov, T.H. 登録日 2011-04-12 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA. Plos One, 7, 2012
3OB7	Human Thymidylate Synthase R163K with Cys 195 covalently modified by Glutathione 分子名称: GLUTATHIONE, PHOSPHATE ION, Thymidylate synthase 著者 Gibson, L.M, Celeste, L.R, Lovelace, L.L, Lebioda, L. 登録日 2010-08-06 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand binding. Acta Crystallogr.,Sect.D, 67, 2011
1TE6	Crystal Structure of Human Neuron Specific Enolase at 1.8 angstrom 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Gamma enolase, ... 著者 Chai, G, Brewer, J, Lovelace, L, Aoki, T, Minor, W, Lebioda, L. 登録日 2004-05-24 公開日 2004-09-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Expression, Purification and the 1.8 A Resolution Crystal Structure of Human Neuron Specific Enolase J.Mol.Biol., 341, 2004
1TEV	Crystal structure of the human UMP/CMP kinase in open conformation 分子名称: SULFATE ION, UMP-CMP kinase 著者 Segura-Pena, D, Sekulic, N, Ort, S, Konrad, M, Lavie, A. 登録日 2004-05-25 公開日 2004-06-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Substrate-induced Conformational Changes in Human UMP/CMP Kinase. J.Biol.Chem., 279, 2004
3ODI	Crystal structure of cyclophilin A in complex with Voclosporin E-ISA247 分子名称: Cyclophilin A, Voclosporin 著者 Kuglstatter, A, Stihle, M, Benz, J, Hennig, M. 登録日 2010-08-11 公開日 2011-02-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin). Acta Crystallogr.,Sect.D, 67, 2011
3ODL	Crystal structure of cyclophilin A in complex with Voclosporin Z-ISA247 分子名称: Cyclophilin A, Voclosporin 著者 Kuglstatter, A, Stihle, M, Benz, J, Hennig, M. 登録日 2010-08-11 公開日 2011-02-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin). Acta Crystallogr.,Sect.D, 67, 2011
3O8V	Crystal Structure of the Tudor Domains from FXR1 分子名称: Fragile X mental retardation syndrome-related protein 1 著者 Lam, R, Guo, Y.H, Adams-Cioaba, M, Bian, C.B, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2010-08-03 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2. Plos One, 5, 2010
1RHO	STRUCTURE OF RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR 分子名称: RHO GDP-DISSOCIATION INHIBITOR 1, SULFATE ION 著者 Keep, N.H, Moody, P.C.E, Roberts, G.C.K. 登録日 1996-10-12 公開日 1997-10-15 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm. Structure, 5, 1997
3R22	Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (Part I) 分子名称: N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide, Serine/threonine-protein kinase 6 著者 Zhang, L, Fan, J, Chong, J.-H, Cesana, A, Tam, B, Gilson, C, Boykin, C, Wang, D, Marcotte, D, Le Brazidec, J.-Y, Aivazian, D, Piao, J, Lundgren, K, Hong, K, Vu, K, Nguyen, K. 登録日 2011-03-11 公開日 2011-08-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I). Bioorg.Med.Chem.Lett., 21, 2011
3RNU	Structural Basis of Cytosolic DNA Sensing by Innate Immune Receptors 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*CP*AP*TP*CP*AP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*CP*TP*TP*TP*GP*AP*TP*GP*GP*CP*C)-3'), ... 著者 Jin, T.C, Xiao, T. 登録日 2011-04-22 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity, 36, 2012
1U3J	Crystal structure of MLAV mutant of dimerisation domain of NF-kB p50 transcription factor 分子名称: Nuclear factor NF-kappa-B p105 subunit 著者 Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. 登録日 2004-07-22 公開日 2004-08-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding Structure, 12, 2004
3ODR	Crystal Structure of the N-terminal Domain of Human Symplekin 分子名称: 1,2-ETHANEDIOL, Symplekin 著者 Tong, L, Xiang, K. 登録日 2010-08-11 公開日 2010-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature, 467, 2010
3QBN	Structure of Human Aurora A in Complex with a diaminopyrimidine 分子名称: 5-chloro-N~4~-cyclopropyl-N~2~-[4-(2-methoxyethoxy)phenyl]pyrimidine-2,4-diamine, Serine/threonine-protein kinase 6 著者 Gruetter, C, Simard, J.R, Rauh, D. 登録日 2011-01-13 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Identification of Ustilago maydis Aurora kinase as a novel antifungal target. Acs Chem.Biol., 6, 2011
3Q6S	The crystal structure of the heterochromatin protein 1 beta chromoshadow domain complexed with a peptide from Shugoshin 1 分子名称: Chromobox protein homolog 1, Shugoshin-like 1 著者 Brautigam, C.A, Chaudhary, J, Yu, H. 登録日 2011-01-03 公開日 2011-12-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells. Mol Biol Cell, 22, 2011
1TYQ	Crystal structure of Arp2/3 complex with bound ATP and calcium 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-related Protein 2, Actin-related protein 3, ... 著者 Nolen, B.J, Littlefield, R.S, Pollard, T.D. 登録日 2004-07-08 公開日 2004-11-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP Proc.Natl.Acad.Sci.Usa, 101, 2004
1UBD	CO-CRYSTAL STRUCTURE OF HUMAN YY1 ZINC FINGER DOMAIN BOUND TO THE ADENO-ASSOCIATED VIRUS P5 INITIATOR ELEMENT 分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*CP*TP*CP*CP*AP*TP*TP*TP*TP*GP*AP*A P*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*CP*AP*AP*AP*AP*TP*GP*GP*AP*GP*AP*C P*CP*CP*T)-3'), PROTEIN (YY1 ZINC FINGER DOMAIN), ... 著者 Houbaviy, H.B, Usheva, A, Shenk, T, Burley, S.K. 登録日 1996-10-04 公開日 1996-12-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator. Proc.Natl.Acad.Sci.USA, 93, 1996
1U76	Crystal structure of hPCNA bound to residues 452-466 of the DNA polymerase-delta-p66 subunit 分子名称: KANRQVSITGFFQRK peptide from DNA polymerase delta subunit 3, Proliferating cell nuclear antigen 著者 Bruning, J.B, Shamoo, Y. 登録日 2004-08-02 公開日 2004-12-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1. Structure, 12, 2004
3QSV	Structural basis for DNA recognition by constitutive Smad4 MH1 dimers 分子名称: DNA (5'-D(P*TP*GP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 4, ZINC ION 著者 Baburajendran, N, Jauch, R, Zhen, C.T.Y, Kolatkar, P.R. 登録日 2011-02-22 公開日 2011-06-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.708 Å) 主引用文献 Structural basis for DNA recognition by constitutive Smad4 MH1 dimers To be Published
3RCW	Crystal Structure of the bromodomain of human BRD1 分子名称: 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, ACETATE ION, ... 著者 Filippakopoulos, P, Keates, T, Picaud, S, Felletar, I, Pike, A.C.W, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-03-31 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012

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