PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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7Q3I	Human Transthyretin expressed in Vibrio natriegens 分子名称: Transthyretin 著者 Hild Walett, O, Hammarstrom, P. 登録日 2021-10-27 公開日 2022-11-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Human Transthyretin expressed in Vibrio natriegens To Be Published
7KW3	Non Ribosomal PCP domain 分子名称: PCP domain, SULFATE ION 著者 Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. 登録日 2020-11-29 公開日 2021-03-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
5V5Z	Structure of CYP51 from the pathogen Candida albicans 分子名称: 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Keniya, M.V, Sabherwal, M, Wilson, R.K, Sagatova, A.A, Tyndall, J.D.A, Monk, B.C. 登録日 2017-03-15 公開日 2017-03-29 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structures of Full-Length Lanosterol 14 alpha-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provide Tools for Antifungal Discovery. Antimicrob.Agents Chemother., 62, 2018
8A85	Structure of the Reconstructed Ancestor of Phenolic Acid Decarboxylase AncPAD134 分子名称: Phenolic acid decarboxylase N134 著者 Mokos, D, Schruefer, A, Gruber, K, Daniel, B. 登録日 2022-06-22 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Reconstructed ancestral sequences of bacterial phenolic acid decarboxylase show increased thermostability To Be Published
8A45	Structural analysis of 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with 2-acetyl thiamine diphosphate 分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 2-ACETYL-THIAMINE DIPHOSPHATE, CALCIUM ION, ... 著者 Hamid, R, Hirsch, A. 登録日 2022-06-10 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding. J.Biol.Chem., 299, 2023
6PR9	S. aureus dihydrofolate reductase co-crystallized with 1-ethylpropyl-dihydropthalazine inhibitor and NADP(H) 分子名称: (2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(pentan-3-yl)-3,4-dihydrophthalazin-2(1H)-yl]prop-2-en-1-one, Dihydrofolate reductase, GLYCEROL, ... 著者 Bourne, C.R, Thomas, L.M. 登録日 2019-07-10 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase. Eur.J.Med.Chem., 200, 2020
6BK5	Inactive choanoflagellate E3 ubiquitin ligase Cbl TKB 分子名称: CALCIUM ION, Ubiquitin Ligase Cbl 著者 Amacher, J.F, Kuriyan, J. 登録日 2017-11-07 公開日 2018-03-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Phosphorylation control of the ubiquitin ligase Cbl is conserved in choanoflagellates. Protein Sci., 27, 2018
8A6W	Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestenone 分子名称: (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, PROTOPORPHYRIN IX CONTAINING FE, Steroid C26-monooxygenase 著者 Snee, M, Amadi, C, Levy, C. 登録日 2022-06-20 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestenone To Be Published
6F6P	Crystal structure of tetrameric human Rabin8 GEF domain 分子名称: Rab-3A-interacting protein 著者 Lorentzen, E, Vetter, M. 登録日 2017-12-06 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of tetrameric human Rabin8 GEF domain. Proteins, 86, 2018
6BIV	HLA-DRB1 in complex with citrullinated LL37 peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... 著者 Ting, Y.T, Scally, S.W, Rossjohn, J. 登録日 2017-11-03 公開日 2018-01-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. J. Biol. Chem., 293, 2018
5H2W	Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-340) 分子名称: Importin subunit alpha, Ubiquitin-like-specific protease 1 著者 Hirano, H, Matsuura, Y. 登録日 2016-10-18 公開日 2016-12-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of the Karyopherins Kap121p and Kap60p Bound to the Nuclear Pore-Targeting Domain of the SUMO Protease Ulp1p J. Mol. Biol., 429, 2017
6BJ9	Crystal structure of Acat2 thiolase from Ascaris suum 分子名称: Acetyl-CoA acetyltransferase A, POTASSIUM ION 著者 Blaisse, M.R, Fu, B, Chang, M.C.Y. 登録日 2017-11-05 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.53014076 Å) 主引用文献 Structural and Biochemical Studies of Substrate Selectivity in Ascaris suum Thiolases. Biochemistry, 57, 2018
5V7O	Crystal Structure of NosK from Streptomyces actuosus 分子名称: NosK, SULFATE ION 著者 Booker, S.J, Boal, A.K, Grove, T.L, Badding, E.D. 登録日 2017-03-20 公開日 2017-04-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Rerouting the Pathway for the Biosynthesis of the Side Ring System of Nosiheptide: The Roles of NosI, NosJ, and NosK. J. Am. Chem. Soc., 139, 2017
8A33	Crystal structure of PpSB1-LOV-K117E mutant (light state) 分子名称: Flavin mononucleotide (semi-quinone intermediate), Sensory box protein 著者 Batra-Safferling, R, Granzin, J, Krauss, U. 登録日 2022-06-07 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structure of PpSB1-LOV-K117E mutant (light state) To Be Published
6JBE	Crystal structure of ABC transporter alpha-glycoside-binding mutant protein W287A in complex with glucose 分子名称: 1,2-ETHANEDIOL, ABC transporter, periplasmic substrate-binding protein, ... 著者 Kanaujia, S.P, Chandravanshi, M, Gogoi, P. 登録日 2019-01-25 公開日 2019-10-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and thermodynamic correlation illuminates the selective transport mechanism of disaccharide alpha-glycosides through ABC transporter. Febs J., 287, 2020
8A37	Crystal structure of PpSB1-LOV-K117E mutant (dark state), tetragonal form 分子名称: DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, Sensory box protein 著者 Batra-Safferling, R, Granzin, J. 登録日 2022-06-07 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Crystal structure of PpSB1-LOV-K117E mutant (dark state), tetragonal form To Be Published
6YOY	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-025 分子名称: 14-3-3 protein sigma, 5-methyl-2-nitrophenol, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-15 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
7KL8	Structure of F420 binding protein Rv1558 from Mycobacterium tuberculosis with F420 bound 分子名称: COENZYME F420, COENZYME F420-3, Deazaflavin-dependent nitroreductase, ... 著者 Lee, B.M, Tan, L.L, Jackson, C.J. 登録日 2020-10-29 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.469 Å) 主引用文献 Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F 420 H 2 -dependent reduction. Proc.Natl.Acad.Sci.USA, 118, 2021
7KW0	Non-ribosomal didomain (stabilised glycine-PCP-C) acceptor bound state 分子名称: N-{2-[(2-aminoethyl)sulfanyl]ethyl}-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, PCP-C didomain 著者 Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. 登録日 2020-11-29 公開日 2021-03-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
6YP2	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-011 分子名称: 1-(4-methylphenyl)imidazole, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-15 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
8A5K	Structural analysis of 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding 分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, CALCIUM ION, GLYCEROL, ... 著者 Hamid, R, Hirsch, A. 登録日 2022-06-15 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding. J.Biol.Chem., 299, 2023
6JCA	Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in I222 space group 分子名称: CHLORIDE ION, CrmG, GLYCEROL, ... 著者 Xu, J, Liu, J. 登録日 2019-01-28 公開日 2020-02-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition. Commun Biol, 3, 2020
6YPC	Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9 angstroms 分子名称: Inner kinetochore subunit CNN1, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, ... 著者 Bellini, D, Zhang, Z, Barford, D. 登録日 2020-04-15 公開日 2020-09-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of the Cenp-HIKHead-TW sub-module of the inner kinetochore CCAN complex. Nucleic Acids Res., 48, 2020
6F81	AKR1B1 at 0.75 MGy radiation dose. 分子名称: Aldose reductase, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Castellvi, A, Juanhuix, J. 登録日 2017-12-12 公開日 2019-03-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation. Sci Rep, 9, 2019
7Q14	Crystal Structure of a Class D Carbapenemase_K73ALY Complexed with Imipenem 分子名称: 1-BUTANOL, BROMIDE ION, Beta-lactamase, ... 著者 Zhou, Q, He, Y, Jin, Y. 登録日 2021-10-18 公開日 2022-11-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023

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