7A5K
| Structure of the human mitoribosome in the post translocation state bound to mtEF-G1 | 分子名称: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | 著者 | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | 登録日 | 2020-08-21 | 公開日 | 2020-12-23 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
|
|
6ZSA
| Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA | 分子名称: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | 著者 | Aibara, S, Singh, V, Modelska, A, Amunts, A. | 登録日 | 2020-07-15 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis of mitochondrial translation. Elife, 9, 2020
|
|
6ZM5
| Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent polypeptide | 分子名称: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | 著者 | Itoh, Y, Andrell, J, Amunts, A. | 登録日 | 2020-07-01 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Mechanism of membrane-tethered mitochondrial protein synthesis. Science, 371, 2021
|
|
6ZSE
| Human mitochondrial ribosome in complex with mRNA, A/P-tRNA and P/E-tRNA | 分子名称: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | 著者 | Aibara, S, Singh, V, Modelska, A, Amunts, A. | 登録日 | 2020-07-15 | 公開日 | 2020-09-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Structural basis of mitochondrial translation. Elife, 9, 2020
|
|
6ZSB
| Human mitochondrial ribosome in complex with mRNA and P-site tRNA | 分子名称: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | 著者 | Aibara, S, Singh, V, Modelska, A, Amunts, A. | 登録日 | 2020-07-15 | 公開日 | 2020-09-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural basis of mitochondrial translation. Elife, 9, 2020
|
|
1XP8
| |
4B8X
| Near atomic resolution crystal structure of Sco5413, a MarR family transcriptional regulator from Streptomyces coelicolor | 分子名称: | CHLORIDE ION, POSSIBLE MARR-TRANSCRIPTIONAL REGULATOR | 著者 | Holley, T.A, Stevenson, C.E.M, Bibb, M.J, Lawson, D.M. | 登録日 | 2012-08-31 | 公開日 | 2012-10-17 | 最終更新日 | 2019-05-22 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | High Resolution Crystal Structure of Sco5413, a Widespread Actinomycete Marr Family Transcriptional Regulator of Unknown Function. Proteins, 81, 2013
|
|
4WT8
| Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex | 分子名称: | 23S rRNA (2899-MER), 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Amunts, A, Fiedorczuk, K, Ramakrishnan, V. | 登録日 | 2014-10-29 | 公開日 | 2015-01-21 | 最終更新日 | 2018-07-18 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics. J.Mol.Biol., 427, 2015
|
|
7A5H
| Structure of the split human mitoribosomal large subunit with rescue factors mtRF-R and MTRES1 | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | 登録日 | 2020-08-21 | 公開日 | 2020-12-23 | 最終更新日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
|
|
8OVX
| Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus | 分子名称: | Inner kinetochore subunit AME1, Inner kinetochore subunit CTF19, Inner kinetochore subunit MCM21, ... | 著者 | Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S. | 登録日 | 2023-04-26 | 公開日 | 2023-08-09 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere. Sci Adv, 9, 2023
|
|
6K5S
| |
2BE2
| Crystal structure of HIV-1 reverse transcriptase (RT) in complex with R221239 | 分子名称: | 4-(3,5-DIMETHYLPHENOXY)-5-(FURAN-2-YLMETHYLSULFANYLMETHYL)-3-IODO-6-METHYLPYRIDIN-2(1H)-ONE, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Himmel, D.M, Das, K, Clark Jr, A.D, Hughes, S.H, Benjahad, A, Oumouch, S, Guillemont, J, Coupa, S, Poncelet, A, Csoka, I, Meyer, C, Andries, K, Nguyen, C.H, Grierson, D.S, Arnold, E. | 登録日 | 2005-10-21 | 公開日 | 2005-12-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains. J.Med.Chem., 48, 2005
|
|
2HDE
| |
2B5J
| Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R165481 | 分子名称: | (2E)-3-{3-[(5-ETHYL-3-IODO-6-METHYL-2-OXO-1,2-DIHYDROPYRIDIN-4-YL)OXY]PHENYL}ACRYLONITRILE, MANGANESE (II) ION, Reverse transcriptase P51 SUBUNIT, ... | 著者 | Himmel, D.H, Das, K, Clark Jr, A.D, Hughes, S.H, Benjahad, A, Oumouch, S, Guillemont, J, Coupa, S, Poncelet, A, Csoka, I, Meyer, C, Andries, K, Mguyen, C.H, Grierson, D.S, Arnold, E. | 登録日 | 2005-09-28 | 公開日 | 2005-12-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains. J.Med.Chem., 48, 2005
|
|
5B32
| The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3. | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | 著者 | Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. | 登録日 | 2016-02-08 | 公開日 | 2016-08-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
|
|
7Y56
| |
7Y57
| |
485D
| |
6TUU
| Leishmania infantum Rad51 surrogate LiRadA10 in complex with 5,6,7,8-tetrahydro-2-naphthoic acid | 分子名称: | 5,6,7,8-tetrahydronaphthalene-2-carboxylic acid, CHLORIDE ION, DNA repair and recombination protein RadA, ... | 著者 | Pantelejevs, T, Hyvonen, M. | 登録日 | 2020-01-08 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Development of dedicated crystallographic systems for structure-guided drug discovery To Be Published
|
|
3SZ5
| Crystal Structure of LHK-Exo in complex with 5-phosphorylated oligothymidine (dT)4 | 分子名称: | 5'-D(P*TP*TP*TP*T)-3', Exonuclease, MAGNESIUM ION | 著者 | Yang, W, Chen, W.Y, Wang, H, Zhang, Q, Zhou, W, Bartlam, M, Watt, R.M, Rao, Z. | 登録日 | 2011-07-18 | 公開日 | 2012-02-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis. Nucleic Acids Res., 39, 2011
|
|
5B31
| The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1. | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | 著者 | Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. | 登録日 | 2016-02-08 | 公開日 | 2016-08-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
|
|
2WAL
| Crystal Structure of human GADD45gamma | 分子名称: | GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA, MALONIC ACID | 著者 | Bhattacharya, S, Mueller, J.J, Roske, Y, Turnbull, A.P, Quedenau, C, Goetz, F, Buessow, K, Heinemann, U. | 登録日 | 2009-02-09 | 公開日 | 2009-03-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Crystal Structure of Human Gadd45Gamma To be Published
|
|
2BAN
| Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R157208 | 分子名称: | 5-ETHYL-3-[(2-METHOXYETHYL)METHYLAMINO]-6-METHYL-4-(3-METHYLBENZYL)PYRIDIN-2(1H)-ONE, MANGANESE (II) ION, Reverse transcriptase P51 subunit, ... | 著者 | Das, K, Arnold, E. | 登録日 | 2005-10-14 | 公開日 | 2005-12-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains. J.Med.Chem., 48, 2005
|
|
6GYG
| |
6J8V
| Structure of MOEN5-SSO7D fusion protein in complex with ligand 2 | 分子名称: | FARNESYL, MoeN5,DNA-binding protein 7d | 著者 | Ko, T.P, Zhang, L.L, Chen, C.C, Guo, R.T. | 登録日 | 2019-01-21 | 公開日 | 2019-04-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism. Biochem. Biophys. Res. Commun., 511, 2019
|
|