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6YA2
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Crystal structure of TSWV glycoprotein N ectodomain (Trypsin treated)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein
著者Dessau, M, Bahat, Y.
登録日2020-03-11
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of tomato spotted wilt virus G N reveals a dimer complex formation and evolutionary link to animal-infecting viruses
Proc.Natl.Acad.Sci.USA, 117, 2020
4WNX
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Netrin 4 lacking the C-terminal Domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者McDougall, M, Patel, T, Reuten, R, Meier, M, Koch, M, Stetefeld, J.
登録日2014-10-14
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.723 Å)
主引用文献Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes.
Nat Commun, 7, 2016
8PE3
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Structure of Csm6' from Streptococcus thermophilus in complex with cyclic hexa-adenylate (cA6)
分子名称: CRISPR system endoribonuclease Csm6', Cyclic hexaadenosine monophosphate (cA6), RNA
著者McQuarrie, S.J, Athukoralage, J.S, McMahon, S.A, Graham, S, Ackerman, K, Bode, B.E, White, M.F, Gloster, T.M.
登録日2023-06-13
公開日2023-10-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open.
Nucleic Acids Res., 51, 2023
8PPL
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BU of 8ppl by Molmil
MERS-CoV Nsp1 bound to the human 43S pre-initiation complex
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
登録日2023-07-07
公開日2023-10-18
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
8PPK
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Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
登録日2023-07-07
公開日2023-10-18
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
8PXC
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Structure of Fap1, a domain of the accessory Sec-dependent serine-rich glycoprotein adhesin from Streptococcus oralis, solved at wavelength 3.06 A
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Fap1
著者El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Owen, C.D, Walsh, M.A, Wagner, A.
登録日2023-07-23
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.973 Å)
主引用文献Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
8PNL
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Outward-open conformation of a Major Facilitator Superfamily (MFS) transporter MHAS2168, a homologue of Rv1410 from M. tuberculosis, in complex with an alpaca nanobody
分子名称: Nb_H2, Putative triacylglyceride transporter
著者Remm, S, Schoeppe, J, Hutter, C.A.J, Gonda, I, Seeger, M.A.
登録日2023-06-30
公開日2023-10-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410.
Nat Commun, 14, 2023
8PXS
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BU of 8pxs by Molmil
Short RNA binding to peptide amyloids
分子名称: RNA (5'-R(P*GP*UP*CP*A)-3'), VAL-ALA-GLN-ALA-GLN-ILE-ASN-ILE
著者Rout, S.K, Cadalbert, R, Schroder, N, Wiegand, T, Zehnder, J, Gampp, O, Guntert, P, Kringler, D, Kreutz, C, Knorlein, A, Hall, J, Greenwald, J, Riek, R.
登録日2023-07-24
公開日2023-10-18
実験手法SOLID-STATE NMR
主引用文献An Analysis of Nucleotide-Amyloid Interactions Reveals Selective Binding to Codon-Sized RNA.
J.Am.Chem.Soc., 145, 2023
8PSB
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Three-layered parallel G-quadruplex with snapback loop from a G-rich sequence with five G-runs
分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*AP*CP*GP*GP*GP*T)-3')
著者Vianney, Y.M, Schroeder, N, Jana, J, Chojetzki, G, Weisz, K.
登録日2023-07-13
公開日2023-09-27
最終更新日2023-10-25
実験手法SOLUTION NMR
主引用文献Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8PWN
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Structure of A2A adenosine receptor A2AR-StaR2-bRIL, solved at wavelength 2.75 A
分子名称: Adenosine receptor A2a,Soluble cytochrome b562, CHOLESTEROL, OLEIC ACID, ...
著者El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Romano, M, Moraes, I, Wagner, A.
登録日2023-07-20
公開日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
1BGQ
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RADICICOL BOUND TO THE ATP BINDING SITE OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE
分子名称: HEAT SHOCK PROTEIN 90, RADICICOL
著者Roe, S.M, Prodromou, C, Pearl, L.H.
登録日1998-05-29
公開日1999-06-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin.
J.Med.Chem., 42, 1999
8Q96
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BU of 8q96 by Molmil
P301S Tau Filaments from the Brains of Tg2541 Transgenic Mouse Line
分子名称: Isoform Tau-E of Microtubule-associated protein tau, Unknown protein
著者Schweighauser, M, Murzin, A.G, Macdonald, J, Lavenir, I, Crowther, R.A, Scheres, S.H.W, Goedert, M.
登録日2023-08-19
公開日2023-10-11
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Acta Neuropathol Commun, 11, 2023
8Q1Q
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BU of 8q1q by Molmil
mouse Keap1 in complex with stapled peptide
分子名称: Kelch-like ECH-associated protein 1, SULFATE ION, Stapled peptide, ...
著者Kack, H, Wissler, L.
登録日2023-08-01
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.378 Å)
主引用文献A cell-active cyclic peptide targeting the Nrf2/Keap1 protein-protein interaction.
Chem Sci, 14, 2023
8Q1R
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BU of 8q1r by Molmil
mouse Keap1 in complex with stapled peptide
分子名称: Kelch-like ECH-associated protein 1, SODIUM ION, SULFATE ION, ...
著者Kack, H, Wissler, L.
登録日2023-08-01
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献A cell-active cyclic peptide targeting the Nrf2/Keap1 protein-protein interaction.
Chem Sci, 14, 2023
4WUX
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BU of 4wux by Molmil
Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D) Complexed with Mannose
分子名称: CALCIUM ION, Pulmonary surfactant-associated protein A, alpha-D-mannopyranose
著者Rynkiewicz, M.J, Wu, H, Cafarella, T.R, Nikolaidis, N.M, Head, J.F, Seaton, B.A, McCormack, F.X.
登録日2014-11-03
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop
To be published
4WV8
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BU of 4wv8 by Molmil
Crystal structure of a recombinant Vatairea macrocarpa seed lectin complexed with lactose
分子名称: CALCIUM ION, MANGANESE (II) ION, Seed lectin, ...
著者Sousa, B.L, Silva-Filho, J.C, Kumar, P, Lyskowski, A, Bezerra, G.A, Delatorre, P, Rocha, B.A.M, Cunha, R.M.S, Nagano, C.S, Gruber, K, Cavada, B.S.
登録日2014-11-04
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural characterization of a Vatairea macrocarpa lectin in complex with a tumor-associated antigen: A new tool for cancer research.
Int.J.Biochem.Cell Biol., 72, 2016
1ARZ
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BU of 1arz by Molmil
ESCHERICHIA COLI DIHYDRODIPICOLINATE REDUCTASE IN COMPLEX WITH NADH AND 2,6 PYRIDINE DICARBOXYLATE
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIHYDRODIPICOLINATE REDUCTASE, PHOSPHATE ION, ...
著者Scapin, G, Reddy, S.G, Zheng, R, Blanchard, J.S.
登録日1997-08-08
公開日1998-10-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase in complex with NADH and the inhibitor 2,6-pyridinedicarboxylate.
Biochemistry, 36, 1997
8PKW
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BU of 8pkw by Molmil
Kelch domain of KEAP1 in complex with a ortho-dimethylbenzene linked cyclic peptide 5 (ortho-WRCDPETaEC).
分子名称: (2-methylphenyl)methanol, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Braun, M.B, Bischof, L, Hartmann, M.D.
登録日2023-06-27
公開日2023-11-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Computational Prediction of Cyclic Peptide Structural Ensembles and Application to the Design of Keap1 Binders.
J.Chem.Inf.Model., 63, 2023
8Q43
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BU of 8q43 by Molmil
Crystal structure of cA4-bound Can2 (E341A) in complex with oligo-C DNA
分子名称: Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*CP*CP*CP*CP*C)-3'), DUF1887 family protein, ...
著者Jungfer, K, Sigg, A, Jinek, M.
登録日2023-08-04
公開日2023-11-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
8PJI
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MLLT1 in complex with compound 10a
分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Protein ENL, ...
著者Raux, B, Diaz-Saez, L, Huber, K.V.M, Fedorov, O, Owen, D.R, Londregan, A.T, Bountra, C, Edwards, A, Arrowsmith, C.
登録日2023-06-23
公開日2023-11-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3.
Bioorg.Med.Chem.Lett., 98, 2023
8Q44
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Crystal structure of cA4-bound Can2 (E364R) in complex with oligo-T DNA
分子名称: Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*TP*T)-3'), DUF1887 family protein, ...
著者Jungfer, K, Sigg, A, Jinek, M.
登録日2023-08-04
公開日2023-11-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
8Q5F
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Crystal structure of miniSOG protein from Arabidopsis thaliana with covalent FMN
分子名称: FLAVIN MONONUCLEOTIDE, miniSOG
著者Rozeboom, H.J, Fraaije, M.W.
登録日2023-08-09
公開日2023-11-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Fixing Flavins: Hijacking a Flavin Transferase for Equipping Flavoproteins with a Covalent Flavin Cofactor.
J.Am.Chem.Soc., 145, 2023
5EWL
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BU of 5ewl by Molmil
CRYSTAL STRUCTURE OF AMINO TERMINAL DOMAINS OF THE NMDA RECEPTOR SUBUNIT GLUN1 AND GLUN2B IN COMPLEX WITH MK-22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 2B, ...
著者Pandit, J.
登録日2015-11-20
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists.
Mol.Pharmacol., 89, 2016
8Q3Z
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Crystal structure of cA4-bound Can2 from Thermoanaerobacter brockii
分子名称: Cyclic tetraadenosine monophosphate (cA4), DUF1887 family protein, MANGANESE (II) ION
著者Jungfer, K, Sigg, A, Jinek, M.
登録日2023-08-04
公開日2023-11-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
4X06
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Crystal structure of P domain from norovirus strain Saga4 in complex with HBGA type B (triglycan)
分子名称: ACETATE ION, VP1, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose
著者Singh, B.K, Hansman, G.S.
登録日2014-11-20
公開日2014-12-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.218 Å)
主引用文献Human noroviruses' fondness for histo-blood group antigens.
J.Virol., 89, 2015

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