8PE3

Structure of Csm6' from Streptococcus thermophilus in complex with cyclic hexa-adenylate (cA6)

Summary for 8PE3

Entry DOI	10.2210/pdb8pe3/pdb
Related	8PCW
Descriptor	CRISPR system endoribonuclease Csm6', Cyclic hexaadenosine monophosphate (cA6), RNA, ... (4 entities in total)
Functional Keywords	carf, hepn, ca6, rnase, rna binding protein
Biological source	Streptococcus thermophilus More
Total number of polymer chains	5
Total formula weight	93988.14
Authors	McQuarrie, S.J.,Athukoralage, J.S.,McMahon, S.A.,Graham, S.,Ackerman, K.,Bode, B.E.,White, M.F.,Gloster, T.M. (deposition date: 2023-06-13, release date: 2023-10-04, Last modification date: 2023-11-08)
Primary citation	McQuarrie, S.,Athukoralage, J.S.,McMahon, S.A.,Graham, S.,Ackermann, K.,Bode, B.E.,White, M.F.,Gloster, T.M. Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open. Nucleic Acids Res., 51:10590-10605, 2023 Cited by PubMed: 37747760 DOI: 10.1093/nar/gkad739 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation