PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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8D3Q	Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/NoPAM prespacer 分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... 著者 Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. 登録日 2022-06-01 公開日 2022-11-02 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. Mol.Cell, 82, 2022
8D3L	Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/PAM prespacer 分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... 著者 Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. 登録日 2022-06-01 公開日 2022-11-02 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. Mol.Cell, 82, 2022
8D3P	Type I-C Cas4-Cas1-Cas2 complex bound to half-site integration intermediate (HSI) 分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... 著者 Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. 登録日 2022-06-01 公開日 2022-11-02 最終更新日 2022-11-30 実験手法 ELECTRON MICROSCOPY (4.26 Å) 主引用文献 PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. Mol.Cell, 82, 2022
1UB1	Solution structure of the matrix attachment region-binding domain of chicken MeCP2 分子名称: attachment region binding protein 著者 Heitmann, B, Maurer, T, Weitzel, J.M, Stratling, W.H, Kalbitzer, H.R, Brunner, E, Structural Proteomics in Europe (SPINE) 登録日 2003-03-27 公開日 2003-08-05 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure of the matrix attachment region-binding domain of chicken MeCP2 EUR.J.BIOCHEM., 270, 2003
6CBQ	Crystal structure of QscR bound to agonist S3 分子名称: (2S)-2-hexyl-N-[(3S)-2-oxooxolan-3-yl]decanamide, LuxR family transcriptional regulator 著者 Churchill, M.E.A, Wysoczynski-Horita, C.L. 登録日 2018-02-05 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands. Mol. Microbiol., 108, 2018
4QYF	CHK1 kinase domain in complex with aminopyrazine compound 13 分子名称: 4-[3-amino-6-(3-hydroxyphenyl)pyrazin-2-yl]benzoic acid, Serine/threonine-protein kinase Chk1 著者 Appleton, B, Wu, P. 登録日 2014-07-24 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1. Bioorg.Med.Chem.Lett., 24, 2014
7OG4	Human mitochondrial ribosome in complex with P/E-tRNA 分子名称: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... 著者 Aibara, S, Singh, V, Modelska, A, Amunts, A. 登録日 2021-05-06 公開日 2021-06-23 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of mitochondrial translation. Elife, 9, 2020
5JEC	Apo-structure of humanised RadA-mutant humRadA33F 分子名称: CHLORIDE ION, DNA repair and recombination protein RadA, SULFATE ION 著者 Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. 登録日 2016-04-18 公開日 2016-10-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
5J4K	Structure of humanised RadA-mutant humRadA22F in complex with 1-Indane-6-carboxylic acid 分子名称: 2,3-dihydro-1H-indene-2-carboxylic acid, CALCIUM ION, DNA repair and recombination protein RadA, ... 著者 Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. 登録日 2016-04-01 公開日 2016-10-26 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.346 Å) 主引用文献 Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
2OXL	Structure and Function of the E. coli Protein YmgB: a Protein Critical for Biofilm Formation and Acid Resistance 分子名称: Hypothetical protein ymgB, octyl beta-D-glucopyranoside 著者 Page, R, Peti, W, Woods, T.K, Palermino, J.M, Doshi, O. 登録日 2007-02-20 公開日 2007-10-30 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and Function of the Escherichia coli Protein YmgB: A Protein Critical for Biofilm Formation and Acid-resistance. J.Mol.Biol., 373, 2007
5CHZ	Structure of wild-type human MBD4 bound to a G:T mismatch 分子名称: 12-mer DNA(G), 5-mer DNA, 7-mer DNA, ... 著者 Ouzon-Shubeita, H, Lin, Y.-L, Lee, S. 登録日 2015-07-10 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structure of wild-type human MBD4 bound to a G:T mismatch To Be Published
1BAM	STRUCTURE OF RESTRICTION ENDONUCLEASE BAMHI PHASED AT 1.95 ANGSTROMS RESOLUTION BY MAD ANALYSIS 分子名称: ENDONUCLEASE BamH I 著者 Aggarwal, A.K, Newman, M. 登録日 1994-12-28 公開日 1995-02-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of restriction endonuclease bamhi phased at 1.95 A resolution by MAD analysis. Structure, 2, 1994
4L5T	Crystal structure of the tetrameric p202 HIN2 分子名称: Interferon-activable protein 202 著者 Yin, Q, Tian, Y, Wu, H. 登録日 2013-06-11 公開日 2013-07-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.405 Å) 主引用文献 Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
6SSQ	Crystal structure of RARbeta LBD in complex with LG 100754 分子名称: (2E,4E,6Z)-3-methyl-7-(5,5,8,8-tetramethyl-3-propoxy-5,6,7,8-tetrahydronaphthalen-2-yl)octa-2,4,6-trienoic acid, CITRATE ANION, GLYCEROL, ... 著者 le Maire, A, Teyssier, C, Germain, P, Bourguet, W. 登録日 2019-09-09 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations. Cells, 8, 2019
8B0Q	Deinococcus radiodurans UvrC C-terminal half 分子名称: UvrABC system protein C 著者 Timmins, J, Stelter, M. 登録日 2022-09-08 公開日 2023-02-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and functional insights into the activation of the dual incision activity of UvrC, a key player in bacterial NER. Nucleic Acids Res., 51, 2023
5LUP	Structures of DHBN domain of human BLM helicase 分子名称: BLM protein, PHOSPHATE ION, POTASSIUM ION 著者 Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. 登録日 2016-09-09 公開日 2017-03-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.032 Å) 主引用文献 A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
6XQJ	Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A 分子名称: Protein Vpr,UV excision repair protein RAD23 homolog A, ZINC ION 著者 Byeon, I.-J.L, Calero, G, Wu, Y, Byeon, C.H, Gronenborn, A.M. 登録日 2020-07-09 公開日 2021-11-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A. Nat Commun, 12, 2021
4QYE	CHK1 kinase domain in complex with diarylpyrazine compound 1 分子名称: 4-[6-(3-hydroxyphenyl)pyrazin-2-yl]benzoic acid, Serine/threonine-protein kinase Chk1 著者 Appleton, B, Wu, P. 登録日 2014-07-24 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1. Bioorg.Med.Chem.Lett., 24, 2014
5M89	Spliceosome component 分子名称: Spliceosome WD40 Sc 著者 Moura, T.R, Pena, V. 登録日 2016-10-28 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.605 Å) 主引用文献 Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018
5M88	Spliceosome component 分子名称: Core 著者 Moura, T.R, Pena, V. 登録日 2016-10-28 公開日 2018-02-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018
7A1F	Crystal structure of human 5' exonuclease Appollo in complex with 5'dAMP 分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 5' exonuclease Apollo, FE (III) ION, ... 著者 Newman, J.A, Baddock, H.T, Mukhopadhyay, S.M.M, Burgess-Brown, N.A, von Delft, F, Arrowshmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2020-08-12 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family. Nucleic Acids Res., 49, 2021
4QYH	CHK1 kinase domain in complex with diazacarbazole GNE-783 分子名称: 3-[4-(4-methylpiperazin-1-yl)phenyl]-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile, Serine/threonine-protein kinase Chk1 著者 Wiesmann, C, Wu, P. 登録日 2014-07-24 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1. Bioorg.Med.Chem.Lett., 24, 2014
5NT5	The effect of Berenil and Cacodylateon the crystal structure of d(CGTGAATTCACG) 分子名称: CACODYLATE ION, DNA (5'-D(*CP*GP*TP*GP*AP*AP*TP*TP*CP*AP*CP*G)-3'), SODIUM ION 著者 Sbirkova, H.I, Shivachev, B.L. 登録日 2017-04-27 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The effect of Berenil and Cacodylateon the crystal structure of d(CGTGAATTCACG) To Be Published
2ARC	ESCHERICHIA COLI REGULATORY PROTEIN ARAC COMPLEXED WITH L-ARABINOSE 分子名称: ARABINOSE OPERON REGULATORY PROTEIN, alpha-L-arabinopyranose 著者 Soisson, S.M, Wolberger, C. 登録日 1996-10-29 公開日 1997-05-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for ligand-regulated oligomerization of AraC. Science, 276, 1997
5JED	Apo-structure of humanised RadA-mutant humRadA28 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... 著者 Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. 登録日 2016-04-18 公開日 2016-10-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.332 Å) 主引用文献 Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

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