8D3P
Type I-C Cas4-Cas1-Cas2 complex bound to half-site integration intermediate (HSI)
Summary for 8D3P
Entry DOI | 10.2210/pdb8d3p/pdb |
EMDB information | 27159 27160 27161 27162 |
Descriptor | CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, HSI strand 2- integrated prespacer strand plus repeat, ... (9 entities in total) |
Functional Keywords | crispr cas adaptation type i-c, hydrolase-dna complex, hydrolase/dna |
Biological source | Alkalihalobacillus halodurans C-125 More |
Total number of polymer chains | 11 |
Total formula weight | 251707.82 |
Authors | Dhingra, Y.,Suresh, S.K.,Juneja, P.,Sashital, D.G. (deposition date: 2022-06-01, release date: 2022-11-02, Last modification date: 2022-11-30) |
Primary citation | Dhingra, Y.,Suresh, S.K.,Juneja, P.,Sashital, D.G. PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. Mol.Cell, 82:4353-, 2022 Cited by PubMed: 36272411DOI: 10.1016/j.molcel.2022.09.030 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.26 Å) |
Structure validation
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