6DME
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![BU of 6dme by Molmil](/molmil-images/mine/6dme) | ppGpp Riboswitch bound to ppGpp, thallium acetate structure | 分子名称: | GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, THALLIUM (I) ION, ... | 著者 | Peselis, A, Serganov, A. | 登録日 | 2018-06-05 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat. Chem. Biol., 14, 2018
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6L3A
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![BU of 6l3a by Molmil](/molmil-images/mine/6l3a) | Cytochrome P450 107G1 (RapN) with everolimus | 分子名称: | Cytochrome P450, Everolimus, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Km, V.C, Kim, D.H, Lim, Y.R, Lee, I.H, Lee, J.H, Kang, L.W. | 登録日 | 2019-10-10 | 公開日 | 2020-09-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus. Arch.Biochem.Biophys., 692, 2020
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2FK5
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![BU of 2fk5 by Molmil](/molmil-images/mine/2fk5) | Crystal structure of l-fuculose-1-phosphate aldolase from Thermus thermophilus HB8 | 分子名称: | CHLORIDE ION, SULFATE ION, fuculose-1-phosphate aldolase | 著者 | Jeyakanthan, J, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-01-04 | 公開日 | 2007-01-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Purification, crystallization and preliminary X-ray crystallographic study of the L-fuculose-1-phosphate aldolase (FucA) from Thermus thermophilus HB8 Acta Crystallogr.,Sect.F, 61, 2005
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2FBP
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![BU of 2fbp by Molmil](/molmil-images/mine/2fbp) | STRUCTURE REFINEMENT OF FRUCTOSE-1,6-BISPHOSPHATASE AND ITS FRUCTOSE 2,6-BISPHOSPHATE COMPLEX AT 2.8 ANGSTROMS RESOLUTION | 分子名称: | FRUCTOSE 1,6-BISPHOSPHATASE | 著者 | Ke, H, Thorpe, C.M, Seaton, B.A, Marcus, F, Lipscomb, W.N. | 登録日 | 1990-06-07 | 公開日 | 1992-04-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure refinement of fructose-1,6-bisphosphatase and its fructose 2,6-bisphosphate complex at 2.8 A resolution. J.Mol.Biol., 212, 1990
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1NQP
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![BU of 1nqp by Molmil](/molmil-images/mine/1nqp) | Crystal structure of Human hemoglobin E at 1.73 A resolution | 分子名称: | CYANIDE ION, Hemoglobin alpha chain, Hemoglobin beta chain, ... | 著者 | Dasgupta, J, Sen, U, Choudhury, D, Dutta, P, Basu, S, Chakrabarti, A, Chakrabarty, A, Dattagupta, J.K. | 登録日 | 2003-01-22 | 公開日 | 2004-03-02 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystallization and preliminary X-ray structural Studies of Hemoglobin A2 and Hemoglobin E, isolated from the blood samples of Beta-thalassemic patients Biochem.Biophys.Res.Commun., 303, 2004
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3O8H
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![BU of 3o8h by Molmil](/molmil-images/mine/3o8h) | EthR from Mycobacterium tuberculosis in complex with compound BDM14950 | 分子名称: | 4-iodo-N-[(1-{2-oxo-2-[4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]ethyl}-1H-1,2,3-triazol-4-yl)methyl]benzenesulfonamide, Transcriptional Regulatory Repressor protein (TETR-Family) EthR | 著者 | Willand, N, Desroses, M, Toto, P, Diri, B, Lens, Z, Villeret, V, Rucktooa, P, Locht, C, Baulard, A, Deprez, B. | 登録日 | 2010-08-03 | 公開日 | 2010-09-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator. Acs Chem.Biol., 5, 2010
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3LMO
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![BU of 3lmo by Molmil](/molmil-images/mine/3lmo) | Crystal Structure of specialized acyl carrier protein (RPA2022) from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR324 | 分子名称: | Specialized acyl carrier protein | 著者 | Forouhar, F, Rossi, P, Lew, S, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-01-31 | 公開日 | 2010-02-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a specialized acyl carrier protein essential for lipid A biosynthesis with very long-chain fatty acids in open and closed conformations. Biochemistry, 51, 2012
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2N70
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![BU of 2n70 by Molmil](/molmil-images/mine/2n70) | Two-fold symmetric structure of the 18-60 construct of S31N M2 from Influenza A in lipid bilayers | 分子名称: | Matrix protein 2 | 著者 | Andreas, L.B, Reese, M, Eddy, M.T, Gelev, V, Ni, Q, Miller, E.A, Emsley, L, Pintacuda, G, Chou, J.J, Griffin, R.G. | 登録日 | 2015-09-01 | 公開日 | 2015-09-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Structure and Mechanism of the Influenza A M218-60 Dimer of Dimers. J.Am.Chem.Soc., 137, 2015
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2FLF
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![BU of 2flf by Molmil](/molmil-images/mine/2flf) | Crystal structure of l-fuculose-1-phosphate aldolase from Thermus Thermophilus HB8 | 分子名称: | fuculose-1-phosphate aldolase | 著者 | Jeyakanthan, J, Yokoyama, S, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-01-06 | 公開日 | 2007-01-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Purification, crystallization and preliminary X-ray crystallographic study of the L-fuculose-1-phosphate aldolase (FucA) from Thermus thermophilus HB8 Acta Crystallogr.,Sect.F, 61, 2005
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2QV6
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![BU of 2qv6 by Molmil](/molmil-images/mine/2qv6) | |
2FVM
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![BU of 2fvm by Molmil](/molmil-images/mine/2fvm) | |
4X89
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![BU of 4x89 by Molmil](/molmil-images/mine/4x89) | NavMs voltage-gated sodium channal pore and C-terminal domain soaked with Silver nitrate | 分子名称: | HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
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8FK4
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![BU of 8fk4 by Molmil](/molmil-images/mine/8fk4) | Structure of the catalytic domain of Streptococcus mutans GtfB complexed to acarbose in orthorhombic space group P21212 | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, Glucosyltransferase-I, ... | 著者 | Schormann, N, Deivanayagam, C. | 登録日 | 2022-12-20 | 公開日 | 2023-05-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis. Acta Crystallogr.,Sect.F, 79, 2023
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8A1A
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![BU of 8a1a by Molmil](/molmil-images/mine/8a1a) | Structure of a leucinostatin derivative determined by host lattice display : L1F11V1 construct | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... | 著者 | Mittl, P.R.E. | 登録日 | 2022-06-01 | 公開日 | 2022-12-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of a hydrophobic leucinostatin derivative determined by host lattice display. Acta Crystallogr D Struct Biol, 78, 2022
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8A19
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![BU of 8a19 by Molmil](/molmil-images/mine/8a19) | Structure of a leucinostatin derivative determined by host lattice display : L1E4V1 construct | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... | 著者 | Mittl, P.R.E. | 登録日 | 2022-06-01 | 公開日 | 2022-12-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.358 Å) | 主引用文献 | Structure of a hydrophobic leucinostatin derivative determined by host lattice display. Acta Crystallogr D Struct Biol, 78, 2022
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5IOY
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![BU of 5ioy by Molmil](/molmil-images/mine/5ioy) | Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with N-(cyclopentylmethyl)pyrrolidine-1-carboxamide at 1.77A resolution | 分子名称: | N-(cyclopentylmethyl)pyrrolidine-1-carboxamide, SULFATE ION, TetR-family transcriptional regulatory repressor protein | 著者 | Blaszczyk, M, Surade, S, Nikiforov, P.O, Abell, C, Blundell, T.L. | 登録日 | 2016-03-09 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays. ACS Chem. Biol., 12, 2017
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5IPA
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![BU of 5ipa by Molmil](/molmil-images/mine/5ipa) | Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with (E)-3-(furan-3-yl)-1-(pyrrolidin-1-yl)prop-2-en-1-one at 1.78A resolution | 分子名称: | (2E)-3-(furan-3-yl)-1-(pyrrolidin-1-yl)prop-2-en-1-one, TetR-family transcriptional regulatory repressor protein | 著者 | Blaszczyk, M, Surade, S, Nikiforov, P.O, Abell, C, Blundell, T.L. | 登録日 | 2016-03-09 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays. ACS Chem. Biol., 12, 2017
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8FX5
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![BU of 8fx5 by Molmil](/molmil-images/mine/8fx5) | Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline | 分子名称: | Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Vuckovic, Z, Mobbs, J.I, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M. | 登録日 | 2023-01-23 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Xanomeline displays concomitant orthosteric and allosteric binding modes at the M 4 mAChR. Nat Commun, 14, 2023
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3QMN
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![BU of 3qmn by Molmil](/molmil-images/mine/3qmn) | Crystal Structure of 4'-Phosphopantetheinyl Transferase AcpS from Vibrio cholerae O1 biovar eltor | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | 著者 | Kim, Y, Halavaty, A.S, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-02-04 | 公開日 | 2011-03-02 | 最終更新日 | 2012-12-05 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria. Acta Crystallogr.,Sect.D, 68, 2012
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6X7R
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![BU of 6x7r by Molmil](/molmil-images/mine/6x7r) | E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) in complex with oxa(dethia)-coenzyme A | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Benjamin, A.B, Stunkard, L.M, Ling, J, Nice, J.N, Lohman, J.R. | 登録日 | 2020-05-30 | 公開日 | 2021-06-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structures of chloramphenicol acetyltransferase III and Escherichia coli beta-keto-acylsynthase III co-crystallized with partially hydrolysed acetyl-oxa(de-thia)CoA Acta Crystallogr.,Sect.F, 2023
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8A7X
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![BU of 8a7x by Molmil](/molmil-images/mine/8a7x) | NaK C-DI F92A mutant soaked in Cs+ | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CESIUM ION, POTASSIUM ION, ... | 著者 | Minniberger, S, Plested, A.J.R. | 登録日 | 2022-06-21 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors. J.Mol.Biol., 435, 2023
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4E95
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![BU of 4e95 by Molmil](/molmil-images/mine/4e95) | Lambda-[Ru(TAP)2(dppz-(Me)2)]2+ bound to CCGGATCCGG | 分子名称: | (11,12-dimethyldipyrido[3,2-a:2',3'-c]phenazine-kappa~2~N~4~,N~5~)[bis(pyrazino[2,3-f]quinoxaline-kappa~2~N~1~,N~10~)]ruthenium(2+), 5'-D(*CP*CP*GP*GP*AP*TP*CP*CP*GP*G)-3', BARIUM ION | 著者 | Hall, J.P, Cardin, C.J. | 登録日 | 2012-03-20 | 公開日 | 2013-03-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | The effects of disubstitution on the binding of ruthenium complexes to DNA Thesis, University of Reading, 2014
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8D1U
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![BU of 8d1u by Molmil](/molmil-images/mine/8d1u) | E. coli beta-ketoacyl-[acyl carrier protein] synthase III (FabH) with an acetylated cysteine and in complex with oxa(dethia)-Coenzyme A | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, CHLORIDE ION, oxa(dethia)-CoA | 著者 | Benjamin, A.B, Stunkard, L.M, Ling, J, Nice, J.N, Lohman, J.R. | 登録日 | 2022-05-27 | 公開日 | 2022-06-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | 主引用文献 | Structures of chloramphenicol acetyltransferase III and Escherichia coli beta-ketoacylsynthase III co-crystallized with partially hydrolysed acetyl-oxa(dethia)CoA. Acta Crystallogr.,Sect.F, 79, 2023
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6UT7
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![BU of 6ut7 by Molmil](/molmil-images/mine/6ut7) | Fitted model for the tetradecameric assembly of Thermococcus gammatolerans McrB AAA+ hexamers with bound McrC | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase subunit of restriction endonuclease, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Niu, Y, Suzuki, H, Hosford, C.J, Chappie, J.S, Walz, T. | 登録日 | 2019-10-29 | 公開日 | 2020-10-21 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.26 Å) | 主引用文献 | Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes. Nat Commun, 11, 2020
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4XGK
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![BU of 4xgk by Molmil](/molmil-images/mine/4xgk) | Crystal structure of UDP-galactopyranose mutase from Corynebacterium diphtheriae in complex with 2-[4-(4-chlorophenyl)-7-(2-thienyl)-2-thia-5,6,8,9-tetrazabicyclo[4.3.0]nona-4,7,9-trien-3-yl]acetic | 分子名称: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, UDP-galactopyranose mutase, ... | 著者 | Wangkanont, K, Heroux, A, Forest, K.T, Kiessling, L.L. | 登録日 | 2014-12-31 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.652 Å) | 主引用文献 | Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents. Acs Chem.Biol., 10, 2015
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