8FK4

Structure of the catalytic domain of Streptococcus mutans GtfB complexed to acarbose in orthorhombic space group P21212

Summary for 8FK4

Entry DOI	10.2210/pdb8fk4/pdb
Related	8FJC 8JF9
Related PRD ID	PRD_900007
Descriptor	Glucosyltransferase-I, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
Functional Keywords	gtfb, gtf-i, insoluble 1, 3-linked alpha glucans, biofilm, streptococcus mutans, glucansucrase, transferase
Biological source	Streptococcus mutans
Total number of polymer chains	8
Total formula weight	789507.93
Authors	Schormann, N.,Deivanayagam, C. (deposition date: 2022-12-20, release date: 2023-05-17)
Primary citation	Schormann, N.,Patel, M.,Thannickal, L.,Purushotham, S.,Wu, R.,Mieher, J.L.,Wu, H.,Deivanayagam, C. The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis Acta Crystallogr.,Sect.F, 79:119-127, 2023 Cited by DOI: 10.1107/S2053230X23003199 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.25 Å)

Structure validation