8FJC
Structure of the catalytic domain of Streptococcus mutans GtfB complexed to acarbose in tetragonal space group P4322
Summary for 8FJC
Entry DOI | 10.2210/pdb8fjc/pdb |
Related | 8FG8 8FJ9 |
Related PRD ID | PRD_900007 |
Descriptor | Glucosyltransferase-I, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | gtfb, gtf-i, insoluble 1, 3-linked alpha glucans, biofilm, glucansucrase, inhibitor acarbose, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Streptococcus mutans |
Total number of polymer chains | 2 |
Total formula weight | 201788.09 |
Authors | Schormann, N.,Deivanayagam, C. (deposition date: 2022-12-19, release date: 2023-05-17, Last modification date: 2024-05-01) |
Primary citation | Schormann, N.,Patel, M.,Thannickal, L.,Purushotham, S.,Wu, R.,Mieher, J.L.,Wu, H.,Deivanayagam, C. The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis. Acta Crystallogr.,Sect.F, 79:119-127, 2023 Cited by PubMed: 37158310DOI: 10.1107/S2053230X23003199 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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