8FJC

Structure of the catalytic domain of Streptococcus mutans GtfB complexed to acarbose in tetragonal space group P4322

Summary for 8FJC

• Entry DOI: 10.2210/pdb8fjc/pdb
• Related: 8FG8 8FJ9
• Related PRD ID: PRD_900007
• Descriptor: Glucosyltransferase-I, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: gtfb, gtf-i, insoluble 1, 3-linked alpha glucans, biofilm, glucansucrase, inhibitor acarbose, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Streptococcus mutans
• Total number of polymer chains: 2
• Total formula weight: 201788.09

Authors

Schormann, N.,Deivanayagam, C. (deposition date: 2022-12-19, release date: 2023-05-17)

• Primary citation: Schormann, N.,Patel, M.,Thannickal, L.,Purushotham, S.,Wu, R.,Mieher, J.L.,Wu, H.,Deivanayagam, C.; The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis; Acta Crystallogr.,Sect.F, 79:119-127, 2023; DOI: 10.1107/S2053230X23003199

Experimental method

X-RAY DIFFRACTION (2.5 Å)