4A7F
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![BU of 4a7f by Molmil](/molmil-images/mine/4a7f) | Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 3) | 分子名称: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S. | 登録日 | 2011-11-14 | 公開日 | 2012-08-01 | 最終更新日 | 2017-08-30 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structure of the Rigor Actin-Tropomyosin-Myosin Complex. Cell(Cambridge,Mass.), 150, 2012
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1CCG
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![BU of 1ccg by Molmil](/molmil-images/mine/1ccg) | CONSTRUCTION OF A BIS-AQUO HEME ENZYME AND REPLACEMENT WITH EXOGENOUS LIGAND | 分子名称: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Mcree, D.E, Jensen, G.M, Fitzgerald, M.M, Siegel, H.A, Goodin, D.B. | 登録日 | 1994-05-04 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Construction of a bisaquo heme enzyme and binding by exogenous ligands. Proc.Natl.Acad.Sci.USA, 91, 1994
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7PQX
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![BU of 7pqx by Molmil](/molmil-images/mine/7pqx) | |
7PSD
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![BU of 7psd by Molmil](/molmil-images/mine/7psd) | |
8TYL
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![BU of 8tyl by Molmil](/molmil-images/mine/8tyl) | |
5LS4
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![BU of 5ls4 by Molmil](/molmil-images/mine/5ls4) | Mopeia virus exonuclease domain complexed with Calcium | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Nucleoprotein, ... | 著者 | Yekwa, E.L, Canard, B, Ferron, F. | 登録日 | 2016-08-22 | 公開日 | 2017-07-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.469 Å) | 主引用文献 | Activity inhibition and crystal polymorphism induced by active-site metal swapping. Acta Crystallogr D Struct Biol, 73, 2017
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6NJT
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![BU of 6njt by Molmil](/molmil-images/mine/6njt) | Mouse endonuclease G mutant - H97A | 分子名称: | CHLORIDE ION, Endonuclease G, mitochondrial, ... | 著者 | Vander Zanden, C.M, Ho, E.N, Czarny, R.S, Robertson, A.B, Ho, P.S. | 登録日 | 2019-01-04 | 公開日 | 2020-01-08 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function. Nucleic Acids Res., 48, 2020
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5CGX
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![BU of 5cgx by Molmil](/molmil-images/mine/5cgx) | CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F complexed with cefoxitin | 分子名称: | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, SODIUM ION, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-09 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | FOX-4 cephamycinase: an analysis of structure and function. Antimicrob.Agents Chemother., 2015
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4K8N
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![BU of 4k8n by Molmil](/molmil-images/mine/4k8n) | Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 18:1 Ceramide-1-Phosphate (18:1-C1P) | 分子名称: | (2S,3R,4Z)-3-hydroxy-2-[(9E)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | 登録日 | 2013-04-18 | 公開日 | 2013-07-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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3N4W
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![BU of 3n4w by Molmil](/molmil-images/mine/3n4w) | Crystal structure of an abridged SER to ALA mutant of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase ICA512/IA-2 at pH 7.5 | 分子名称: | CALCIUM ION, Receptor-type tyrosine-protein phosphatase-like N | 著者 | Primo, M.E, Jakoncic, J, Poskus, E, Ermacora, M.R. | 登録日 | 2010-05-23 | 公開日 | 2010-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2. J.Biol.Chem., 283, 2008
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7XC7
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![BU of 7xc7 by Molmil](/molmil-images/mine/7xc7) | Cryo-EM structure of a bacterial protein complex | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-23 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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7X8A
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![BU of 7x8a by Molmil](/molmil-images/mine/7x8a) | Cryo-EM structure of a bacterial protein complex | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-11 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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1CCE
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![BU of 1cce by Molmil](/molmil-images/mine/1cce) | CONSTRUCTION OF A BIS-AQUO HEME ENZYME AND REPLACEMENT WITH EXOGENOUS LIGAND | 分子名称: | CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Mcree, D.E, Jensen, G.M, Fitzgerald, M.M, Siegel, H.A, Goodin, D.B. | 登録日 | 1994-05-04 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Construction of a bisaquo heme enzyme and binding by exogenous ligands. Proc.Natl.Acad.Sci.USA, 91, 1994
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6T8N
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![BU of 6t8n by Molmil](/molmil-images/mine/6t8n) | Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K3007 | 分子名称: | 1,2-ETHANEDIOL, Activin receptor type I, DIMETHYL SULFOXIDE, ... | 著者 | Adamson, R.J, Williams, E.P, Bonomo, S, Rankin, S, Bacos, D, Rae, A, Cramp, S, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | 登録日 | 2019-10-24 | 公開日 | 2019-11-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K3007 To Be Published
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6T8V
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![BU of 6t8v by Molmil](/molmil-images/mine/6t8v) | Complement factor B in complex with (S)-5,7-Dimethyl-4-((2-phenylpiperidin-1-yl)methyl)-1H-indole | 分子名称: | 4-[(2~{S})-1-[(5,7-dimethyl-1~{H}-indol-4-yl)methyl]piperidin-2-yl]benzoic acid, Complement factor B, SULFATE ION, ... | 著者 | Mainolfi, N, Ehara, T, Karki, R.G, Anderson, K, Mac Sweeney, A, Wiesmann, C, Adams, C, Mainolfi, N, Liao, S.-M, Argikar, U.A, Jendza, K, Zhang, C, Powers, J, Klosowski, D.W, Crowley, M, Kawanami, T, Ding, J, April, M, Forster, C, Serrano-Wu, M, Capparelli, M, Ramqaj, R, Solovay, C, Cumin, F, Smith, T.M, Ferrara, L, Lee, W, Long, D, Prentiss, M, De Erkenez, A, Yang, L, Fang, L, Sellner, H, Sirockin, F, Valeur, E, Erbel, P, Ramage, P, Gerhartz, B, Schubart, A, Flohr, S, Gradoux, N, Feifel, R, Vogg, B, Wiesmann, C, Maibaum, J, Eder, J, Sedrani, R, Harrison, R.A, Mogi, M, Jaffee, B.D, Adams, C.M. | 登録日 | 2019-10-25 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases. J.Med.Chem., 63, 2020
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2B05
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![BU of 2b05 by Molmil](/molmil-images/mine/2b05) | Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide | 分子名称: | 14-3-3 protein gamma, peptide | 著者 | Papagrigoriou, E, Elkins, J, Arrowsmith, C, Zhao, Y, Debreczeni, E.J, Edwards, A, Weigelt, J, Doyle, D, von Delft, F, Turnbull, A, Yang, X. | 登録日 | 2005-09-13 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide TO BE PUBLISHED
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4KF6
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![BU of 4kf6 by Molmil](/molmil-images/mine/4kf6) | Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 8:0 Ceramide-1-Phosphate (8:0-C1P) | 分子名称: | (2S,3R,4E)-3-hydroxy-2-(octanoylamino)octadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | 登録日 | 2013-04-26 | 公開日 | 2013-07-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.195 Å) | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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2GHE
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![BU of 2ghe by Molmil](/molmil-images/mine/2ghe) | Conformational mobility in the active site of a heme peroxidase | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, cytosolic ascorbate peroxidase 1 | 著者 | Badyal, S.K, Joyce, M.G, Sharp, K.H, Raven, E.L, Moody, P.C.E. | 登録日 | 2006-03-27 | 公開日 | 2006-06-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Conformational Mobility in the Active Site of a Heme Peroxidase. J.Biol.Chem., 281, 2006
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7X7A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x7a by Molmil](/molmil-images/mine/7x7a) | Cryo-EM structure of SbCas7-11 in complex with crRNA and target RNA | 分子名称: | RAMP superfamily protein, RNA (33-MER), ZINC ION | 著者 | Yu, G, Wang, X, Deng, Z, Zhang, H. | 登録日 | 2022-03-09 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex. Nat Microbiol, 7, 2022
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6NW7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nw7 by Molmil](/molmil-images/mine/6nw7) | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with S-Adenosyl-L-homocysteine | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Thomas, S.E, Whitehouse, A.J, Coyne, A.G, Abell, C, Mendes, V, Blundell, T.L. | 登録日 | 2019-02-06 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.481 Å) | 主引用文献 | Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification. Nucleic Acids Res., 48, 2020
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3JWB
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![BU of 3jwb by Molmil](/molmil-images/mine/3jwb) | Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with norleucine | 分子名称: | DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, NORLEUCINE | 著者 | Revtovish, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V. | 登録日 | 2009-09-18 | 公開日 | 2010-09-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Three-dimensional structures of noncovalent complexes of Citrobacter freundii methionine gamma-lyase with substrates. Biochemistry Mosc., 76, 2011
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5WDA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wda by Molmil](/molmil-images/mine/5wda) | Structure of the PulG pseudopilus | 分子名称: | CALCIUM ION, General secretion pathway protein G | 著者 | Lopez-Castilla, A, Thomassin, J.L, Bardiaux, B, Zheng, W, Nivaskumar, M, Yu, X, Nilges, M, Egelman, E.H, Izadi-Pruneyre, N, Francetic, O. | 登録日 | 2017-07-04 | 公開日 | 2017-10-25 | 最終更新日 | 2020-01-01 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Structure of the calcium-dependent type 2 secretion pseudopilus. Nat Microbiol, 2, 2017
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2AGI
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![BU of 2agi by Molmil](/molmil-images/mine/2agi) | The leupeptin-trypsin covalent complex at 1.14 A resolution | 分子名称: | CALCIUM ION, SULFATE ION, beta-trypsin, ... | 著者 | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | 登録日 | 2005-07-26 | 公開日 | 2006-05-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103, 2006
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6NKE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nke by Molmil](/molmil-images/mine/6nke) | Wild-type GGGPS from Thermoplasma volcanium | 分子名称: | GLYCEROL, Geranylgeranylglyceryl phosphate synthase, IMIDAZOLE, ... | 著者 | Blank, P.N, Alderfer, K.E, Gillott, B.N, Christianson, D.W, Himmelberger, J.A. | 登録日 | 2019-01-07 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Structural studies of geranylgeranylglyceryl phosphate synthase, a prenyltransferase found in thermophilic Euryarchaeota. Acta Crystallogr D Struct Biol, 76, 2020
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1KLG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1klg by Molmil](/molmil-images/mine/1klg) | Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | 分子名称: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | 著者 | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | 登録日 | 2001-12-11 | 公開日 | 2002-08-02 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line. J.Mol.Biol., 319, 2002
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