6T8N

Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K3007

Summary for 6T8N

• Entry DOI: 10.2210/pdb6t8n/pdb
• Descriptor: Activin receptor type I, 1,2-ETHANEDIOL, SULFATE ION, ... (7 entities in total)
• Functional Keywords: kinase, bmp, inhibitor, signalling, signaling protein
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 70861.29

Authors

Adamson, R.J.,Williams, E.P.,Bonomo, S.,Rankin, S.,Bacos, D.,Rae, A.,Cramp, S.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. (deposition date: 2019-10-24, release date: 2019-11-27, Last modification date: 2024-01-24)

• Primary citation: Adamson, R.J.,Williams, E.P.,Smil, D.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N.; Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K3007; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.77 Å)