PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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6NVY	Crystal structure of penicillin G acylase from Bacillus thermotolerans 分子名称: CALCIUM ION, GLYCEROL, Penicillin G acylase 著者 Blankenfeldt, W. 登録日 2019-02-05 公開日 2019-07-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Crystal structures and protein engineering of three different penicillin G acylases from Gram-positive bacteria with different thermostability. Appl.Microbiol.Biotechnol., 103, 2019
6CWJ	Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica complexed with 1,3-Acetone Dicarboxylic Acid 分子名称: 1,3-PROPANDIOL, 3-oxopentanedioic acid, ACETATE ION, ... 著者 Shi, K, Aihara, H. 登録日 2018-03-30 公開日 2019-06-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.253 Å) 主引用文献 Crystal structures of Moorella thermoacetica cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis. Plos One, 14, 2019
6O1I	Alpha-L-fucosidase AlfC fucosyltransferase mutant E274A 分子名称: AlfC 著者 Klontz, E.H, Sundberg, E.J. 登録日 2019-02-20 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation. Nat Commun, 11, 2020
6D3K	Crystal structure of unphosphorylated human PKR kinase domain in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced, double-stranded RNA-activated protein kinase, ... 著者 Erlandsen, H, Mayo, C.B, Robinson, V.L, Cole, J.L. 登録日 2018-04-16 公開日 2019-07-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis of Protein Kinase R Autophosphorylation. Biochemistry, 58, 2019
6D9E	Crystal structure of Corynebacterium diphtheriae UDP-galactopyranose mutase in complex with UDP-GlcNAc (open, reduced) 分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, ISOPROPYL ALCOHOL, SODIUM ION, ... 著者 Wangkanont, K, Kiessling, L.L, Forest, K.T. 登録日 2018-04-28 公開日 2019-05-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Substrate recognition by FAD in UDP-galactopyranose mutase To be published
6QLX	Cathepsin-K in complex with fluoro-oxa-azabicyclo[3.3.0]octanyl containing inhibitor 分子名称: Cathepsin K, ~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{S},6~{a}~{S})-6-fluoranyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-thiophen-2-yl-benzamide 著者 Derbyshire, D.J. 登録日 2019-02-01 公開日 2020-02-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K. To Be Published
6O1J	Alpha-L-fucosidase AlfC fucosyltransferase mutant N243A 分子名称: AlfC, beta-L-fucopyranose 著者 Klontz, E.H, Sundberg, E.J. 登録日 2019-02-20 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation. Nat Commun, 11, 2020
6O1A	Alpha-L-fucosidase AlfC from Lactobacillus casei in complex with alpha-L-fucose product 分子名称: AlfC, beta-L-fucopyranose 著者 Klontz, E.H, Sundberg, E.J. 登録日 2019-02-18 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation. Nat Commun, 11, 2020
6O21	Crystal Structure of Human KLK4 in Complex With Cleaved SFTI-FCQR(Asn14)[1,14] Inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Kallikrein 4 (Prostase, enamel matrix, ... 著者 Ilyichova, O.V, Buckle, A.M. 登録日 2019-02-22 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors. Biochemistry, 58, 2019
6NLK	1.85 A resolution structure of WT BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor (analog 13) 分子名称: 4-{[3-(4-hydroxyphenyl)propyl]amino}-1H-isoindole-1,3(2H)-dione, FE (II) ION, Ferroxidase, ... 著者 Lovell, S, Punchi-Hewage, A, Battaile, K.P, Yao, H, Nammalwar, B, Gnanasekaran, K.K, Bunce, R.A, Reitz, A.B, Rivera, M. 登録日 2019-01-08 公開日 2019-05-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity. J.Am.Chem.Soc., 141, 2019
6NNE	Crystal structure of Dihydrofolate reductase from Mycobacterium tuberculosis in complex with diaverdine 分子名称: 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine, COBALT (II) ION, Dihydrofolate reductase, ... 著者 Ribeiro, J.A, Chavez-Pacheco, S.M, Dias, M.V.B. 登録日 2019-01-14 公開日 2019-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.595 Å) 主引用文献 Crystal structures of the closed form of Mycobacterium tuberculosis dihydrofolate reductase in complex with dihydrofolate and antifolates. Acta Crystallogr D Struct Biol, 75, 2019
7RKA	Crystal structure analysis of Colorado potato beetle glutathione-S transferase LdGSTu1 分子名称: GLUTATHIONE, glutathione S-transferase u1 著者 Moural, T.W, Zhu, F. 登録日 2021-07-22 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and Functional Characterization of One Unclassified Glutathione S-Transferase in Xenobiotic Adaptation of Leptinotarsa decemlineata. Int J Mol Sci, 22, 2021
6QXL	Crystal Structure of Pyruvate Kinase II (PykA) from Pseudomonas aeruginosa in complex with sodium malonate, magnesium and glucose-6-phosphate 分子名称: 6-O-phosphono-alpha-D-glucopyranose, GLYCEROL, MAGNESIUM ION, ... 著者 Abdelhamid, Y, Brear, P, Welch, M. 登録日 2019-03-07 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Evolutionary plasticity in the allosteric regulator-binding site of pyruvate kinase isoform PykA fromPseudomonas aeruginosa. J.Biol.Chem., 294, 2019
6QZJ	Crystal structure of human Aquaporin 7 at 2.2 A resolution 分子名称: Aquaporin-7, GLYCEROL, PHOSPHATE ION 著者 de Mare, S.W.-H, Venskutonyte, R, Eltschkner, S, Lindkvist-Petersson, K. 登録日 2019-03-11 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7. Structure, 28, 2020
4OMN	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128E 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4OMQ	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant S94A 分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2015-01-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation To be Published
4ON3	Crystal structure of human sorting nexin 10 (SNX10) 分子名称: NITRATE ION, PENTAETHYLENE GLYCOL, SODIUM ION, ... 著者 Xu, T, Xu, J, Wang, Q, Liu, J. 登録日 2014-01-28 公開日 2014-09-24 最終更新日 2014-12-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis. Proteins, 82, 2014
6QLW	Cathepsin-K in complex with MIV-710 分子名称: CHLORIDE ION, Cathepsin K, SODIUM ION, ... 著者 Derbyshire, D.J. 登録日 2019-02-01 公開日 2020-02-19 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K. To Be Published
6KKL	Crystal structure of Drug:Proton Antiporter-1 (DHA1) Family SotB, in the inward conformation (H115N mutant) 分子名称: Sugar efflux transporter, nonyl beta-D-glucopyranoside 著者 Xiao, Q.J, Sun, B, Zuo, Y.X, Guo, L, He, J.H, Deng, D. 登録日 2019-07-26 公開日 2020-07-29 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.654 Å) 主引用文献 Visualizing the nonlinear changes of a drug-proton antiporter from inward-open to occluded state. Biochem.Biophys.Res.Commun., 534, 2021
7RJR	Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with BCLTF1 分子名称: 1,2-ETHANEDIOL, Bcl-2-associated transcription factor 1, Bromodomain-containing protein 4, ... 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization To Be Published
7RJO	Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with hnRNPK 分子名称: ACETATE ION, Bromodomain-containing protein 4, GLYCEROL, ... 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv, 2021
7RJL	Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with SHMT 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, GLYCEROL, ... 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv, 2021
7RJK	Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with hnRNPK 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, GLYCEROL, ... 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv, 2021
4OMP	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K 分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
7RJN	Crystal structure of human bromodomain containing protein 3 (BRD3) in complex with BCLTF1 分子名称: 1,2-ETHANEDIOL, Bcl-2-associated transcription factor 1, Bromodomain-containing protein 3 著者 Fedorov, E, Islam, K, Ghosh, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv, 2021

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