PDB: 2832 件ウェブページステータス検索Chemie searchBIRD

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8P2K	Ternary complex of translating ribosome, NAC and METAP1 分子名称: 18s rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Jia, M, Jaskolowski, M, Scaiola, A, Jomaa, A, Ban, N. 登録日 2023-05-16 公開日 2023-07-19 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 NAC controls cotranslational N-terminal methionine excision in eukaryotes. Science, 380, 2023
6LU8	Cryo-EM structure of a human pre-60S ribosomal subunit - state A 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. 登録日 2020-01-26 公開日 2020-08-26 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
6LSS	Cryo-EM structure of a pre-60S ribosomal subunit - state preA 分子名称: 28S rRNA, 5S rRNA, 60S ribosomal protein L11, ... 著者 Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. 登録日 2020-01-20 公開日 2020-08-26 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
2RE8	Glutaminyl-tRNA synthetase mutant C229R with bound analog 5'-O-[N-(L-GLUTAMYL)-SULFAMOYL]ADENOSINE 分子名称: Glutamine tRNA, Glutaminyl-tRNA synthetase, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ... 著者 Bullock, T.L, Perona, J.J. 登録日 2007-09-25 公開日 2008-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A rationally engineered misacylating aminoacyl-tRNA synthetase. Proc.Natl.Acad.Sci.Usa, 105, 2008
5UPL	CDC42 binds PAK4 via an extended GTPase-effector inteface - 2 peptide: PAK4FL, CDC42 - UNREFINED 分子名称: Cell division control protein 42 homolog, Serine/threonine-protein kinase PAK 4 著者 Ha, B.H, Boggon, T.J. 登録日 2017-02-03 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.003 Å) 主引用文献 CDC42 binds PAK4 via an extended GTPase-effector interface. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5UPK	CDC42 binds PAK4 via an extended GTPase-effector interface - 3 peptide: PAK4cat, PAK4-N45, CDC42 分子名称: Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Ha, B.H, Boggon, T.J. 登録日 2017-02-03 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 CDC42 binds PAK4 via an extended GTPase-effector interface. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7QWS	Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. 登録日 2022-01-25 公開日 2022-03-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
4R62	Structure of Rad6~Ub 分子名称: ACETATE ION, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 2 著者 Kumar, P, Wolberger, C. 登録日 2014-08-22 公開日 2015-09-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity. Nucleic Acids Res., 43, 2015
5EML	Crystal structure of PRMT5:MEP50 with Compound 10 and SAM 分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ... 著者 Boriack-Sjodin, P.A, Jin, L. 登録日 2015-11-06 公開日 2016-02-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666. ACS Med Chem Lett, 7, 2016
5EMK	Crystal structure of PRMT5:MEP50 with Compound 9 and sinefungin 分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ... 著者 Boriack-Sjodin, P.A, Jin, L. 登録日 2015-11-06 公開日 2016-02-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666. ACS Med Chem Lett, 7, 2016
5EMJ	Crystal structure of PRMT5:MEP50 with Compound 8 and sinefungin 分子名称: (2~{S})-1-(3,4-dihydro-1~{H}-isoquinolin-2-yl)-3-[[4-(3-methylbenzimidazol-5-yl)pyridin-2-yl]amino]propan-2-ol, GLYCEROL, Methylosome protein 50, ... 著者 Boriack-Sjodin, P.A, Jin, L. 登録日 2015-11-06 公開日 2016-02-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.273 Å) 主引用文献 Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666. ACS Med Chem Lett, 7, 2016
7MDZ	80S rabbit ribosome stalled with benzamide-CHX 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S21, ... 著者 Koga, Y, Hoang, E.M, Park, Y, Keszei, A.F.A, Murray, J, Shao, S, Liau, B.B. 登録日 2021-04-06 公開日 2021-09-01 最終更新日 2021-09-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. J.Am.Chem.Soc., 143, 2021
5A2Q	Structure of the HCV IRES bound to the human ribosome 分子名称: 18S RRNA, HCV IRES, MAGNESIUM ION, ... 著者 Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. 登録日 2015-05-21 公開日 2015-07-15 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
5EMM	Crystal structure of PRMT5:MEP50 with Compound 15 and sinefungin 分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ... 著者 Boriack-Sjodin, P.A, Jin, L. 登録日 2015-11-06 公開日 2016-02-24 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666. ACS Med Chem Lett, 7, 2016
7NWI	Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S 分子名称: 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ... 著者 Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. 登録日 2021-03-16 公開日 2021-07-07 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
7NWG	Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. 分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... 著者 Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. 登録日 2021-03-16 公開日 2021-07-07 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
2DU3	Crystal structure of Archaeoglobus fulgidus O-phosphoseryl-tRNA synthetase complexed with tRNACys and O-phosphoserine 分子名称: O-phosphoseryl-tRNA synthetase, PHOSPHOSERINE, tRNA 著者 Fukunaga, R. 登録日 2006-07-20 公開日 2007-03-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea. Nat.Struct.Mol.Biol., 14, 2007
2DU4	Crystal structure of Archaeoglobus fulgidus O-phosphoseryl-tRNA synthetase complexed with tRNACys 分子名称: O-phosphoseryl-tRNA synthetase, tRNA 著者 Fukunaga, R. 登録日 2006-07-20 公開日 2007-03-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea. Nat.Struct.Mol.Biol., 14, 2007
1WQ3	Escherichia coli tyrosyl-tRNA synthetase mutant complexed with 3-iodo-L-tyrosine 分子名称: 3-IODO-TYROSINE, Tyrosyl-tRNA synthetase 著者 Kobayashi, T, Sakamoto, K, Nureki, O, Takimura, T, Kamata, K, Sekine, R, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-09-20 公開日 2005-01-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion Proc.Natl.Acad.Sci.USA, 102, 2005
6T59	Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Lin, Z, Gasic, I, Chandrasekaran, V, Peters, N, Shao, S, Ramakrishnan, V, Mitchison, T.J, Hegde, R.S. 登録日 2019-10-15 公開日 2019-11-27 最終更新日 2020-01-15 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 TTC5 mediates autoregulation of tubulin via mRNA degradation. Science, 367, 2020
6LQM	Cryo-EM structure of a pre-60S ribosomal subunit - state C 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. 登録日 2020-01-14 公開日 2020-08-26 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
2DU5	Crystal structure of Archaeoglobus fulgidus O-phosphoseryl-tRNA synthetase E418N/E420N mutant complexed with tRNAOpal and O-phosphoserine ("opal complex") 分子名称: O-phosphoseryl-tRNA synthetase, PHOSPHOSERINE, tRNA 著者 Fukunaga, R. 登録日 2006-07-20 公開日 2007-03-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea. Nat.Struct.Mol.Biol., 14, 2007
2DU6	Crystal structure of Archaeoglobus fulgidus O-phosphoseryl-tRNA synthetase E418N/E420N mutant complexed with tRNAAmber and O-phosphoserine ("amber complex") 分子名称: O-phosphoseryl-tRNA synthetase, PHOSPHOSERINE, tRNA 著者 Fukunaga, R. 登録日 2006-07-20 公開日 2007-03-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea. Nat.Struct.Mol.Biol., 14, 2007
8CSG	Human PRMT5:MEP50 structure with Fragment 1 and MTA Bound 分子名称: 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, 6-bromo-1H-pyrrolo[3,2-b]pyridin-5-amine, ... 著者 Gunn, R.J, Lawson, J.D, Smith, C.R. 登録日 2022-05-12 公開日 2022-10-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
3AFH	Crystal structure of Thermotoga maritima nondiscriminating glutamyl-tRNA synthetase in complex with a glutamyl-AMP analog 分子名称: Glutamyl-tRNA synthetase 2, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE 著者 Ito, T, Yokoyama, S. 登録日 2010-03-01 公開日 2010-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of nondiscriminating glutamyl-tRNA synthetase from Thermotoga maritima Acta Crystallogr.,Sect.D, 66, 2010

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