PDB: 35881 件ウェブページステータス検索Chemie searchBIRD

---

6D21	Crystal structure of the FERM domain of zebrafish FARP2 分子名称: FERM, RhoGEF and pleckstrin domain protein 2 著者 Kuo, Y.C, Zhang, X. 登録日 2018-04-12 公開日 2018-07-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Structural analyses of FERM domain-mediated membrane localization of FARP1. Sci Rep, 8, 2018
1UP4	Structure of the 6-phospho-beta glucosidase from Thermotoga maritima at 2.85 Angstrom resolution in the monoclinic form 分子名称: 6-PHOSPHO-BETA-GLUCOSIDASE 著者 Varrot, A, Yip, V, Withers, S.G, Davies, G.J. 登録日 2003-09-26 公開日 2004-11-18 最終更新日 2016-12-28 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Nad+ and Metal-Ion Dependent Hydrolysis by Family 4 Glycosidases: Structural Insight Into Specificity for Phospho-Beta-D-Glucosides J.Mol.Biol., 346, 2005
2F9Q	Crystal Structure of Human Cytochrome P450 2D6 分子名称: Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Rowland, P. 登録日 2005-12-06 公開日 2005-12-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 Crystal Structure of Human Cytochrome P450 2D6 J.Biol.Chem., 281, 2006
2FDV	Microsomal P450 2A6 with the inhibitor N-Methyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound 分子名称: 1,2-ETHANEDIOL, Cytochrome P450 2A6, N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE, ... 著者 Yano, J.K, Stout, C.D, Johnson, E.F. 登録日 2005-12-14 公開日 2006-11-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization. J.Med.Chem., 49, 2006
4C6I	Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 7.0 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ... 著者 Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. 登録日 2013-09-18 公開日 2014-01-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
4P81	Structure of ancestral PyrR protein (AncORANGEPyrR) 分子名称: Ancestral PyrR protein (Orange), GLYCEROL, SULFATE ION 著者 Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. 登録日 2014-03-29 公開日 2014-12-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
1V4B	The crystal structure of AzoR (Azo Reductase) from Escherichia coli: Oxidized form 分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, ISOPROPYL ALCOHOL, ... 著者 Ito, K, Tanokura, M. 登録日 2003-11-12 公開日 2005-01-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Three-dimensional structure of AzoR from Escherichia coli. An oxidereductase conserved in microorganisms J.Biol.Chem., 281, 2006
6CUE	Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody vFP7.04 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... 著者 Acharya, P, Carragher, B, Potter, C.S, Kwong, P.D. 登録日 2018-03-26 公開日 2018-07-11 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV. PLoS Pathog., 14, 2018
1UP6	Structure of the 6-phospho-beta glucosidase from Thermotoga maritima at 2.55 Angstrom resolution in the tetragonal form with manganese, NAD+ and glucose-6-phosphate 分子名称: 6-O-phosphono-alpha-D-glucopyranose, 6-PHOSPHO-BETA-GLUCOSIDASE, MANGANESE (II) ION, ... 著者 Varrot, A, Yip, V.L, Withers, S.G, Davies, G.J. 登録日 2003-09-29 公開日 2004-08-02 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 An Unusual Mechanism of Glycoside Hydrolysis Involving Redox and Elimination Steps by a Family 4 Beta-Glycosidase from Thermotoga Maritima. J.Am.Chem.Soc., 126, 2004
4P82	Structure of PyrR protein from Bacillus subtilis 分子名称: Bifunctional protein PyrR, SULFATE ION 著者 Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. 登録日 2014-03-30 公開日 2014-12-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
6CX4	V180A Mutant of Yeast PCNA 分子名称: Proliferating cell nuclear antigen 著者 Powers, K.T. 登録日 2018-04-02 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.081 Å) 主引用文献 Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis. PLoS ONE, 11, 2016
7NMH	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-070 分子名称: (5-methanoyl-2-nitro-phenyl) methanesulfonate, 14-3-3 protein sigma, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-23 公開日 2021-09-15 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
6BTI	Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with N-arachidonoylethanolamine (AEA) 分子名称: (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide, DI(HYDROXYETHYL)ETHER, Retinol-binding protein 2 著者 Silvaroli, J.A, Blaner, W.S, Lodowski, D.T, Golczak, M. 登録日 2017-12-06 公開日 2018-12-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight. Sci Adv, 6, 2020
6BX5	The crystal structure of fluoride channel Fluc Ec2 with Monobody S12 分子名称: FLUORIDE ION, Monobody S12, Putative fluoride ion transporter CrcB, ... 著者 Turman, D.L, Miller, C. 登録日 2017-12-17 公開日 2018-02-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Molecular Interactions between a Fluoride Ion Channel and Synthetic Protein Blockers. Biochemistry, 57, 2018
2FDY	Microsomal P450 2A6 with the inhibitor Adrithiol bound 分子名称: 4,4'-DIPYRIDYL DISULFIDE, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Yano, J.K, Stout, C.D, Johnson, E.F. 登録日 2005-12-14 公開日 2006-11-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization. J.Med.Chem., 49, 2006
6QKZ	Full length GluA1/2-gamma8 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, ... 著者 Herguedas, B, Garcia-Nafria, J, Greger, I.G. 登録日 2019-01-30 公開日 2019-03-27 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8. Science, 364, 2019
6BYK	Structure of 14-3-3 beta/alpha bound to O-ClcNAc peptide 分子名称: 14-3-3 protein beta/alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose, ATPPVSQASSTT O-GlcNac peptide 著者 Schumacher, M.A. 登録日 2017-12-20 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Proc.Natl.Acad.Sci.USA, 115, 2018
6C05	Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. 登録日 2017-12-27 公開日 2018-03-28 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (5.15 Å) 主引用文献 Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
6QDT	Crystal structure of 14-3-3sigma in complex with a RapGef2 pT740 phosphopeptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C. 登録日 2019-01-02 公開日 2020-01-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth. Cell Chem Biol, 27, 2020
6QKC	GluA1/2 In complex with auxiliary subunit gamma-8 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 1, ... 著者 Herguedas, B, Garcia-Nafria, J, Greger, I.G. 登録日 2019-01-28 公開日 2019-03-27 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8. Science, 364, 2019
6QDS	Crystal structure of 14-3-3sigma in complex with a PAK6 pT99 phosphopeptide stabilized by semi-synthetic fusicoccane FC-NCPC 分子名称: 14-3-3 protein sigma, CHLORIDE ION, FC-NCPC, ... 著者 Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C. 登録日 2019-01-02 公開日 2020-01-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth. Cell Chem Biol, 27, 2020
4TNU	Human brain aspartoacylase mutant Y231C complex with intermediate analog (N-phosphonomethyl-L-aspartate) 分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION 著者 Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E. 登録日 2014-06-05 公開日 2014-07-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective. Biochemistry, 53, 2014
6CJK	Anti HIV Fab 10A 分子名称: ACETATE ION, GLYCEROL, Immunoglobulin Fab heavy chain, ... 著者 Hangartner, L, Ward, A.B, Wilson, I.A, Oyen, D. 登録日 2018-02-26 公開日 2018-08-15 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.795 Å) 主引用文献 Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity, 49, 2018
3GUG	Crystal structure of AKR1C1 L308V mutant in complex with NADP and 3,5-dichlorosalicylic acid 分子名称: 3,5-dichloro-2-hydroxybenzoic acid, Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Dhagat, U, El-Kabbani, O. 登録日 2009-03-30 公開日 2010-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of AKR1C1 L308V mutant in complex with NADP and 3,5-dichlorosalicylic acid To be Published
6CCO	Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 3-((1S,2S)-2-(4-hydroxy-1H-benzo[d]imidazol-2-yl)cyclopentyl)benzoic acid 分子名称: 3-[(1S,2S)-2-(7-hydroxy-1H-benzimidazol-2-yl)cyclopentyl]benzoic acid, Phosphopantetheine adenylyltransferase, SULFATE ION 著者 Mamo, M, Appleton, B.A. 登録日 2018-02-07 公開日 2018-03-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria. J. Med. Chem., 61, 2018

<742743744745746747748749750751752753754755756757>