PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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6OZW	Crystal structure of the 65-kilodalton amino-terminal fragment of DNA topoisomerase I from Streptococcus mutans 分子名称: DNA topoisomerase 1, FORMIC ACID, MAGNESIUM ION 著者 Jones, J.A, Hevener, K.E. 登録日 2019-05-16 公開日 2019-06-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.063 Å) 主引用文献 Crystal structure of the 65-kilodalton amino-terminal fragment of DNA topoisomerase I from the gram-positive model organism Streptococcus mutans. Biochem.Biophys.Res.Commun., 516, 2019
6YOW	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521 分子名称: 14-3-3 protein sigma, 4-(methylsulfonyl)benzaldehyde, p65pS45 著者 Wolter, M, Ottmann, C. 登録日 2020-04-15 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
7O58	Human phosphomannomutase 2 (PMM2) with mutation T237M in complex with the activator glucose 1,6-bisphosphate 分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... 著者 Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. 登録日 2021-04-08 公開日 2022-02-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
2BVM	Crystal structure of the catalytic domain of toxin B from Clostridium difficile in complex with UDP, Glc and manganese ion 分子名称: MANGANESE (II) ION, SULFATE ION, TOXIN B, ... 著者 Reinert, D.J, Jank, T, Aktories, K, Schulz, G.E. 登録日 2005-06-30 公開日 2005-08-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural Basis for the Function of Clostridium Difficile Toxin B. J.Mol.Biol., 351, 2005
4XZU	Crystal Structure of the Human Factor VIII C2 Domain in Complex with Murine 3E6 Inhibitory Antibody 分子名称: 3E6 antibody Fab heavy chain, 3E6 antibody Fab light chain, Coagulation factor VIII, ... 著者 Spiegel, P.C, Wuerth, M.E. 登録日 2015-02-05 公開日 2015-12-09 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structure of the Human Factor VIII C2 Domain in Complex with the 3E6 Inhibitory Antibody. Sci Rep, 5, 2015
7WKS	Apo state of AtPIN3 分子名称: Auxin efflux carrier component 3 著者 Su, N. 登録日 2022-01-11 公開日 2022-08-10 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures and mechanisms of the Arabidopsis auxin transporter PIN3. Nature, 609, 2022
7WKW	NPA bound state of AtPIN3 分子名称: 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 3 著者 Su, N. 登録日 2022-01-11 公開日 2022-08-10 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.62 Å) 主引用文献 Structures and mechanisms of the Arabidopsis auxin transporter PIN3. Nature, 609, 2022
4Y2G	Structure of BRCA1 BRCT domains in complex with Abraxas single phosphorylated peptide 分子名称: BRCA1-A complex subunit Abraxas, Breast cancer type 1 susceptibility protein 著者 Wu, Q, Blundell, T.L. 登録日 2015-02-09 公開日 2016-01-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites. Mol.Cell, 61, 2016
6YMM	Crystal structure of the SAM-SAH riboswitch with SAM from space group P312 分子名称: Chains: A, Chains: B,D, S-ADENOSYLMETHIONINE, ... 著者 Huang, L, Lilley, D.M.J. 登録日 2020-04-08 公開日 2020-07-22 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure and ligand-induced folding of the SAM/SAH riboswitch. Nucleic Acids Res., 48, 2020
7Q86	Crystal structure of human peroxisomal acyl-Co-A oxidase 1a, FAD-bound-form 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Isoform 2 of Peroxisomal acyl-coenzyme A oxidase 1 著者 Sonani, R.R, Blat, A, Dubin, G. 登録日 2021-11-10 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal structures of apo- and FAD-bound human peroxisomal acyl-CoA oxidase provide mechanistic basis explaining clinical observations. Int.J.Biol.Macromol., 205, 2022
7QH6	Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 1 分子名称: 16S ribosomal RNA, 39S ribosomal protein L13, mitochondrial, ... 著者 Rebelo-Guiomar, P, Pellegrino, S, Dent, K.C, Warren, A.J, Minczuk, M. 登録日 2021-12-10 公開日 2022-03-02 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. Nat Commun, 13, 2022
4QL7	Crystal structure of C-terminus truncated Alkylhydroperoxide Reductase subunit C (AhpC1-172) from E. coli 分子名称: Alkylhydroperoxide Reductase subunit C 著者 Kamariah, N, Gruber, G, Eisenhaber, F, Eisenhaber, B. 登録日 2014-06-11 公開日 2014-09-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.75 Å) 主引用文献 Key roles of the Escherichia coli AhpC C-terminus in assembly and catalysis of alkylhydroperoxide reductase, an enzyme essential for the alleviation of oxidative stress. Biochim.Biophys.Acta, 1837, 2014
4XWJ	Histidine-containing phosphocarrier protein (HPr) and antisigma factor Rsd complex 分子名称: Phosphocarrier protein HPr, Regulator of sigma D 著者 Um, S.H, Seok, Y.J, Ha, N.C. 登録日 2015-01-29 公開日 2015-10-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.095 Å) 主引用文献 Structural basis for the sequestration of the anti-sigma (70) factor Rsd from sigma (70) by the histidine-containing phosphocarrier protein HPr. Acta Crystallogr.,Sect.D, 71, 2015
7W64	Crystal structure of minor pilin TcpB from Vibrio cholerae complexed with N-terminal peptide fragment of TcpF 分子名称: CALCIUM ION, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... 著者 Oki, H, Kawahara, K, Iimori, M, Imoto, Y, Maruno, T, Uchiyama, S, Muroga, Y, Yoshida, A, Yoshida, T, Ohkubo, T, Matsuda, S, Iida, T, Nakamura, S. 登録日 2021-12-01 公開日 2022-11-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the toxin-coregulated pilus-dependent secretion of Vibrio cholerae colonization factor. Sci Adv, 8, 2022
4XWT	Crystal structure of RNase J complexed with UMP 分子名称: DR2417, GLYCEROL, MANGANESE (II) ION, ... 著者 Lu, M, Zhang, H, Xu, Q, Hua, Y, Zhao, Y. 登録日 2015-01-29 公開日 2015-12-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J Nucleic Acids Res., 43, 2015
6YPL	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-037 分子名称: (2-methylsulfonylphenyl)methanol, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-16 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
6P6D	HUMAN IGG1 FC FRAGMENT, C239 INSERTION MUTANT 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, IgG1 Fc fragment 著者 Gallagher, D.T, Dimasi, N, McCullough, C. 登録日 2019-06-03 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Structure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions. Pharmaceutics, 11, 2019
7Q84	Crystal structure of human peroxisomal acyl-Co-A oxidase 1a, apo-form 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Sonani, R.R, Blat, A, Dubin, G. 登録日 2021-11-10 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of apo- and FAD-bound human peroxisomal acyl-CoA oxidase provide mechanistic basis explaining clinical observations. Int.J.Biol.Macromol., 205, 2022
4QIK	Crystal structure of the ROQ domain of human Roquin in complex with the TNF23 RNA duplex 分子名称: 5'-R(*AP*C*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3', CHLORIDE ION, GLYCEROL, ... 著者 Tan, D, Tong, L. 登録日 2014-05-31 公開日 2014-07-16 最終更新日 2014-08-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA. Nat.Struct.Mol.Biol., 21, 2014
7W65	Crystal structure of minor pilin TcpB from Vibrio cholerae complexed with secreted protein TcpF 分子名称: Toxin coregulated pilus biosynthesis protein F, Toxin-coregulated pilus biosynthesis protein B 著者 Oki, H, Kawahara, K, Iimori, M, Imoto, Y, Maruno, T, Uchiyama, S, Muroga, Y, Yoshida, A, Yoshida, T, Ohkubo, T, Matsuda, S, Iida, T, Nakamura, S. 登録日 2021-12-01 公開日 2022-11-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (4.05 Å) 主引用文献 Structural basis for the toxin-coregulated pilus-dependent secretion of Vibrio cholerae colonization factor. Sci Adv, 8, 2022
7W63	Crystal structure of minor pilin TcpB from Vibrio cholerae 分子名称: SULFATE ION, Toxin-coregulated pilus biosynthesis protein B 著者 Oki, H, Kawahara, K, Iimori, M, Imoto, Y, Maruno, T, Uchiyama, S, Muroga, Y, Yoshida, A, Yoshida, T, Ohkubo, T, Matsuda, S, Iida, T, Nakamura, S. 登録日 2021-12-01 公開日 2022-11-09 最終更新日 2022-11-16 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structural basis for the toxin-coregulated pilus-dependent secretion of Vibrio cholerae colonization factor. Sci Adv, 8, 2022
7OEW	Hepatitis B core protein mutant F97L with bound MHRSLLGRMKGA 分子名称: Capsid protein, MHRSLLGRMKGA 著者 Makbul, C, Bottcher, B. 登録日 2021-05-04 公開日 2022-03-16 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Conformational Plasticity of Hepatitis B Core Protein Spikes Promotes Peptide Binding Independent of the Secretion Phenotype. Microorganisms, 9, 2021
7WG3	Structural basis of interleukin-17B receptor in complex with a neutralizing antibody D9 for guiding humanization and affinity maturation for cancer therapy 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D9 Fab, IL17RB protein, ... 著者 Lee, W.H, Chen, X.R, Liu, I.J, Lee, J.H, Hu, C.M, Wu, H.C, Wang, S.K, Lee, W.H, Ma, C. 登録日 2021-12-28 公開日 2022-11-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation. Cell Rep, 41, 2022
1PGU	YEAST ACTIN INTERACTING PROTEIN 1 (AIP1), Se-Met PROTEIN, MONOCLINIC CRYSTAL FORM 分子名称: Actin interacting protein 1, ZINC ION 著者 Voegtli, W.C, Madrona, A.Y, Wilson, D.K. 登録日 2003-05-28 公開日 2003-07-15 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization. J.Biol.Chem., 278, 2003
4QL9	Crystal structure of C-terminus truncated Alkylhydroperoxide Reductase subunit C (AhpC1-182) from E. coli 分子名称: Alkylhydroperoxide Reductase subunit C 著者 Nartey, W, Kamariah, N, Gruber, G. 登録日 2014-06-11 公開日 2014-09-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Key roles of the Escherichia coli AhpC C-terminus in assembly and catalysis of alkylhydroperoxide reductase, an enzyme essential for the alleviation of oxidative stress. Biochim.Biophys.Acta, 1837, 2014

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