PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

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4QQ5	Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex With FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations 分子名称: Fibroblast growth factor receptor 4, N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide 著者 Huang, Z, Mohammadi, M. 登録日 2014-06-26 公開日 2014-10-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.203 Å) 主引用文献 DFG-out Mode of Inhibition by an Irreversible Type-1 Inhibitor Capable of Overcoming Gate-Keeper Mutations in FGF Receptors. Acs Chem.Biol., 10, 2015
6SW9	IC2A model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Coureux, P.-D, Mechulam, Y, Schmitt, E. 登録日 2019-09-20 公開日 2020-02-19 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation. Commun Biol, 3, 2020
1LE4	STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E 分子名称: APOLIPOPROTEIN E4 著者 Wilson, C, Agard, D.A. 登録日 1991-08-22 公開日 1992-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms. J.Biol.Chem., 269, 1994
1O0B	CRYSTAL STRUCTURE OF L-GLUTAMINE AND AMPCPP BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE 分子名称: ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl tRNA, ... 著者 Bullock, T.L, Perona, J.J. 登録日 2003-02-20 公開日 2003-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Amino Acid Discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants J.Mol.Biol., 328, 2003
1L35	STRUCTURE OF A THERMOSTABLE DISULFIDE-BRIDGE MUTANT OF PHAGE T4 LYSOZYME SHOWS THAT AN ENGINEERED CROSSLINK IN A FLEXIBLE REGION DOES NOT INCREASE THE RIGIDITY OF THE FOLDED PROTEIN 分子名称: T4 LYSOZYME 著者 Pjura, P.E, Matsumura, M, Wozniak, J.A, Matthews, B.W. 登録日 1989-10-26 公開日 1990-01-15 最終更新日 2022-11-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a thermostable disulfide-bridge mutant of phage T4 lysozyme shows that an engineered cross-link in a flexible region does not increase the rigidity of the folded protein. Biochemistry, 29, 1990
1H24	CDK2/CyclinA in complex with a 9 residue recruitment peptide from E2F 分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, TRANSCRIPTION FACTOR E2F1 著者 Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N. 登録日 2002-07-31 公開日 2003-02-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A Biochemistry, 41, 2002
1L54	THE STRUCTURAL AND THERMODYNAMIC CONSEQUENCES OF BURYING A CHARGED RESIDUE WITHIN THE HYDROPHOBIC CORE OF T4 LYSOZYME 分子名称: T4 LYSOZYME 著者 Daopin, S, Matthews, B.W. 登録日 1991-01-28 公開日 1991-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and thermodynamic consequences of burying a charged residue within the hydrophobic core of T4 lysozyme. Biochemistry, 30, 1991
5KP8	Crystal Structure of the Curacin Biosynthetic Pathway HMG Synthase in Complex with Acetyl Donor-ACP 分子名称: 4'-PHOSPHOPANTETHEINE, CurB, CurD, ... 著者 Maloney, F.P, Smith, J.L. 登録日 2016-07-02 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Anatomy of the beta-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate. Proc.Natl.Acad.Sci.USA, 113, 2016
1L6V	STRUCTURE OF REDUCED BOVINE ADRENODOXIN 分子名称: Adrenodoxin 1, FE2/S2 (INORGANIC) CLUSTER 著者 Beilke, D, Weiss, R, Lohr, F, Pristovsek, P, Hannemann, F, Bernhardt, R, Rueterjans, H. 登録日 2002-03-14 公開日 2002-06-26 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A new electron transport mechanism in mitochondrial steroid hydroxylase systems based on structural changes upon the reduction of adrenodoxin. Biochemistry, 41, 2002
1H28	CDK2/CyclinA in complex with an 11-residue recruitment peptide from p107 分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, RETINOBLASTOMA-LIKE PROTEIN 1 著者 Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N. 登録日 2002-07-31 公開日 2003-02-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A Biochemistry, 41, 2002
6UBY	Isolated cofilin bound to an actin filament 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Huehn, A.R, Bibeau, J.P, Schramm, A.C, Cao, W, De La Cruz, E.M, Sindelar, C.V. 登録日 2019-09-13 公開日 2020-01-01 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (7.5 Å) 主引用文献 Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments. Proc.Natl.Acad.Sci.USA, 117, 2020
1LNH	LIPOXYGENASE-3(SOYBEAN) NON-HEME FE(II) METALLOPROTEIN 分子名称: FE (II) ION, LIPOXYGENASE-3 著者 Skrzypczak-Jankun, E. 登録日 1996-03-29 公開日 1997-02-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme. Proteins, 29, 1997
1LRP	COMPARISON OF THE STRUCTURES OF CRO AND LAMBDA REPRESSOR PROTEINS FROM BACTERIOPHAGE LAMBDA 分子名称: LAMBDA REPRESSOR 著者 Pabo, C, Lewis, M. 登録日 1987-12-04 公開日 1989-01-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Comparison of the structures of cro and lambda repressor proteins from bacteriophage lambda. J.Mol.Biol., 169, 1983
1A34	SATELLITE TOBACCO MOSAIC VIRUS/RNA COMPLEX 分子名称: PROTEIN (SATELLITE TOBACCO MOSAIC VIRUS), RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ... 著者 Larson, S.B, Day, J, Greenwood, A.J, McPherson, A. 登録日 1998-01-28 公開日 1998-04-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Refined structure of satellite tobacco mosaic virus at 1.8 A resolution. J.Mol.Biol., 277, 1998
1ODL	PURINE NUCLEOSIDE PHOSPHORYLASE FROM THERMUS THERMOPHILUS 分子名称: CHLORIDE ION, GLYCEROL, PURINE NUCLEOSIDE PHOSPHORYLASE, ... 著者 Tahirov, T.H, Inagaki, E, Miyano, M. 登録日 2003-02-19 公開日 2003-02-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Purine Nucleoside Phosphorylase from Thermus Thermophilus J.Mol.Biol., 337, 2004
5JKK	Crystal structure of the negatively supercharged variant Ftn(neg) of human heavy chain ferritin 分子名称: CHLORIDE ION, FE (III) ION, Ferritin heavy chain, ... 著者 Kuenzle, M, Beck, T. 登録日 2016-04-26 公開日 2017-05-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Metal-Assisted Assembly of Protein Containers Loaded with Inorganic Nanoparticles. Inorg.Chem., 57, 2018
1H2I	Human Rad52 protein, N-terminal domain 分子名称: DNA REPAIR PROTEIN RAD52 HOMOLOG 著者 Singleton, M.R, Wentzell, L.M, Liu, Y, West, S.C, Wigley, D.B. 登録日 2002-08-09 公開日 2002-10-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the Single-Strand Annealing Domain of Human Rad52 Protein Proc.Natl.Acad.Sci.USA, 99, 2002
5UQ3	Crystal structure of human Cdk2-Spy1-P27 ternary complex 分子名称: Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B, Speedy protein A 著者 McGrath, D.A, Tripathi, S.M, Rubin, S.M. 登録日 2017-02-06 公開日 2017-07-05 最終更新日 2017-08-09 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins. EMBO J., 36, 2017
5JIO	Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase ternary complex with ADP and Glucose-6-phosphate. 分子名称: 1,2-ETHANEDIOL, 6-O-phosphono-alpha-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Mendes, V, Verma, N, Blaszczyk, M, Blundell, T.L. 登録日 2016-04-22 公開日 2017-05-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.711 Å) 主引用文献 Mycobacterial OtsA Structures Unveil Substrate Preference Mechanism and Allosteric Regulation by 2-Oxoglutarate and 2-Phosphoglycerate. Mbio, 10, 2019
1AAP	X-RAY CRYSTAL STRUCTURE OF THE PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR 分子名称: ALZHEIMER'S DISEASE AMYLOID A4 PROTEIN 著者 Hynes, T.R, Randal, M, Kennedy, L.A, Eigenbrot, C, Kossiakoff, A.A. 登録日 1990-09-14 公開日 1991-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid beta-protein precursor. Biochemistry, 29, 1990
4AH2	HLA-DR1 with covalently linked CLIP106-120 in canonical orientation 分子名称: GLYCEROL, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN,DRB1-1 BETA CHAIN, ... 著者 Schlundt, A, Guenther, S, Sticht, J, Wieczorek, M, Roske, Y, Heinemann, U, Freund, C. 登録日 2012-02-03 公開日 2012-08-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Peptide Linkage to the Alpha-Subunit of Mhcii Creates a Stably Inverted Antigen Presentation Complex. J.Mol.Biol., 423, 2012
8HMD	base module state 2 of Tetrahymena IFT-A 分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... 著者 Ma, Y, Wu, J, Lei, M. 登録日 2022-12-03 公開日 2023-06-14 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
8HMC	base module state 1 of Tetrahymena IFT-A 分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... 著者 Ma, Y, Wu, J, Lei, M. 登録日 2022-12-03 公開日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
1BRQ	CRYSTAL STRUCTURE OF THE TRIGONAL FORM OF HUMAN PLASMA RETINOL-BINDING PROTEIN AT 2.5 ANGSTROMS RESOLUTION 分子名称: RETINOL BINDING PROTEIN 著者 Zanotti, G, Monaco, H.L. 登録日 1992-07-27 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the trigonal form of human plasma retinol-binding protein at 2.5 A resolution. J.Mol.Biol., 230, 1993
1BYM	SOLUTION STRUCTURES OF THE C-TERMINAL DOMAIN OF DIPHTHERIA TOXIN REPRESSOR 分子名称: PROTEIN (DIPHTHERIA TOXIN REPRESSOR) 著者 Wang, G, Wylie, G.P, Twigg, P.D, Caspar, D.L.D, Murphy, J.R, Logan, T.M. 登録日 1998-10-17 公開日 1998-10-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and peptide binding studies of the C-terminal src homology 3-like domain of the diphtheria toxin repressor protein. Proc.Natl.Acad.Sci.USA, 96, 1999

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