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3UD7
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Crystal Structure Analysis of FGF1-Disaccharide(NI21) complexes
分子名称: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION
著者Hung, S.-C, Shi, Z.
登録日2011-10-27
公開日2012-11-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction
J.Am.Chem.Soc., 134, 2012
4OAU
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Complete human RNase L in complex with biological activators.
分子名称: 2-5A-dependent ribonuclease, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Han, Y, Donovan, J, Rath, S, Whitney, G, Chitrakar, A, Korennykh, A.
登録日2014-01-06
公開日2014-03-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response.
Science, 343, 2014
3UWV
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Crystal structure of Staphylococcus Aureus triosephosphate isomerase complexed with 2-phosphoglyceric acid
分子名称: 2-PHOSPHOGLYCERIC ACID, SODIUM ION, Triosephosphate isomerase
著者Mukherjee, S, Roychowdhury, A, Dutta, D, Das, A.K.
登録日2011-12-03
公開日2012-10-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Crystal structures of triosephosphate isomerase from methicillin resistant Staphylococcus aureus MRSA252 provide structural insights into novel modes of ligand binding and unique conformations of catalytic loop
Biochimie, 94, 2012
4OB9
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Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.50A resolution
分子名称: Chorismate synthase
著者Shukla, P.K, Chaudhary, A, Singh, N, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
登録日2014-01-07
公開日2014-01-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.50A resolution
To be Published
3UX9
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Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
分子名称: Interferon alpha-1/13, ScFv antibody
著者Ouyang, S, Zhao, L.X, Liang, W, Shaw, N, Liu, Z.-J, Liang, M.-F.
登録日2011-12-04
公開日2012-02-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
J.Mol.Med., 2012
3UY5
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crystal structure of Eis from Mycobacterium tuberculosis
分子名称: Enhanced intracellular survival protein
著者Kim, K.H, Suh, S.W.
登録日2011-12-05
公開日2012-05-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mycobacterium tuberculosis Eis protein initiates suppression of host immune responses by acetylation of DUSP16/MKP-7
Proc.Natl.Acad.Sci.USA, 2012
4OUM
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Crystal structure of human Caprin-2 C1q domain
分子名称: CITRATE ANION, Caprin-2, ISOPROPYL ALCOHOL, ...
著者Song, X, Li, L.
登録日2014-02-18
公開日2014-10-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.491 Å)
主引用文献Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling
J.Biol.Chem., 289, 2014
3UYC
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Designed protein KE59 R8_2/7A
分子名称: Kemp eliminase KE59 R8_2/7A, PHOSPHATE ION
著者Khersonsky, O, Kiss, G, Roethlisberger, D, Dym, O, Albeck, S, Houk, K.N, Baker, D, Tawfik, D.S, Israel Structural Proteomics Center (ISPC)
登録日2011-12-06
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59.
Proc.Natl.Acad.Sci.USA, 109, 2012
4OV1
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The crystal structure of a novel electron transfer ferredoxin from R. palustris HaA2
分子名称: FE3-S4 CLUSTER, Putative ferredoxin
著者Zhouw, W.H, Zhang, T, Zhang, A.L, Bell, S.G, Wong, L.-L.
登録日2014-02-19
公開日2014-05-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献The structure of a novel electron-transfer ferredoxin from Rhodopseudomonas palustris HaA2 which contains a histidine residue in its iron-sulfur cluster-binding motif.
Acta Crystallogr.,Sect.D, 70, 2014
3UYV
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Crystal structure of a glycosylated ice-binding protein (LeIBP) from Arctic yeast
分子名称: Antifreeze protein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Lee, J.H, Park, A.K, Do, H, Park, K.S, Moh, S.H, Chi, Y.M, Kim, H.J.
登録日2011-12-06
公開日2012-02-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural basis for the antifreeze activity of an ice-binding protein from an Arctic yeast.
J.Biol.Chem., 2012
4OC2
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X-ray structure of of human glutamate carboxypeptidase II (GCPII) in a complex with CEIBzL, a urea-based inhibitor N~2~-{[(1S)-1-carboxybut-3-yn-1-yl]carbamoyl}-N~6~-(4-iodobenzoyl)-L-lysine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Pavlicek, J, Ptacek, J, Cerny, J, Byun, Y, Skultetyova, L, Pomper, M, Lubkowski, J, Barinka, C.
登録日2014-01-08
公開日2014-05-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural characterization of P1'-diversified urea-based inhibitors of glutamate carboxypeptidase II.
Bioorg.Med.Chem.Lett., 24, 2014
3UCF
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Crystal structure of a small-chain dehydrogenase
分子名称: Dehydrogenase
著者Buysschaert, G, Verstraete, K, Savvides, S, Vergauwen, B.
登録日2011-10-26
公開日2013-01-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.347 Å)
主引用文献Structural and biochemical characterization of an atypical short-chain dehydrogenase/reductase reveals an unusual cofactor preference.
Febs J., 280, 2013
4ODA
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Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminus
分子名称: DNA polymerase processivity factor component A20, GLYCEROL, SULFATE ION, ...
著者Contesto-Richefeu, C, Tarbouriech, N, Brazzolotto, X, Burmeister, W.P, Iseni, F.
登録日2014-01-10
公開日2014-03-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit d4 in complex with the a20 N-terminal domain.
Plos Pathog., 10, 2014
3UE8
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Kynurenine Aminotransferase II Inhibitors
分子名称: (5-hydroxy-4-{[(1-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Kynurenine/alpha-aminoadipate aminotransferase, ...
著者Dounay, A.B, Anderson, M, Bechle, B.M, Campbell, B.M, Claffey, M.M, Evdokimov, A, Edelweiss, E, Fonseca, K.R, Gan, X, Ghosh, S, Hayward, M.M, Horner, W, Kim, J.Y, McAllister, L.A, Pandit, J, Paradis, V, Parikh, V.D, Reese, M.R, Rong, S.B, Salafia, M.A, Schuyten, K, Strick, C.A, Tuttle, J.B, Valentine, J, Wang, H, Zawadzke, L.E, Verhoest, P.R.
登録日2011-10-28
公開日2012-02-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia.
ACS Med Chem Lett, 3, 2012
3UCU
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The c-di-GMP-I riboswitch bound to pGpG
分子名称: MAGNESIUM ION, RNA (92-MER), U1 small nuclear ribonucleoprotein A, ...
著者Smith, K.D, Strobel, S.A.
登録日2011-10-27
公開日2012-01-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer.
Biochemistry, 51, 2012
4FUJ
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Crystal Structure of the Urokinase
分子名称: 6-{(E)-2-[3-(2-hydroxyethyl)phenyl]ethenyl}naphthalene-2-carboximidamide, ACETATE ION, GLYCEROL, ...
著者Kang, Y.N, Stuckey, J.A, Nienaber, V, Giranda, V.
登録日2012-06-28
公開日2012-08-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of the Urokinase
TO BE PUBLISHED
4OVL
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Interrogating HIV integrase for compounds that bind- a SAMPL challenge
分子名称: 1,2-ETHANEDIOL, 3-[(E)-(2-oxidanylidene-1H-indol-3-ylidene)methyl]benzoic acid, ACETIC ACID, ...
著者Peat, T.S.
登録日2013-11-21
公開日2014-03-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Interrogating HIV integrase for compounds that bind--a SAMPL challenge.
J. Comput. Aided Mol. Des., 28, 2014
4ODQ
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Structure of SlyD delta-IF from Thermus thermophilus in complex with S3 peptide
分子名称: 30S ribosomal protein S3, CALCIUM ION, CHLORIDE ION, ...
著者Quistgaard, E.M, Low, C, Nordlund, P.
登録日2014-01-10
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD.
BMC Biol., 14, 2016
3UD1
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Crystal structure of ZU5A-ZU5B domains of human erythrocyte ankyrin
分子名称: Ankyrin-1, ETHANOL
著者Yasunaga, M, Ipsaro, J.J, Mondragon, A.
登録日2011-10-27
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structurally Similar but Functionally Diverse ZU5 Domains in Human Erythrocyte Ankyrin.
J.Mol.Biol., 417, 2012
4ODX
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4E10 germline encoded precursor no.7 in complex with epitope scaffold T117
分子名称: 4E10 epitope scaffold T117, GEP7 Fv heavy chain, GEP7 Fv light chain
著者Finton, K.A.K.
登録日2014-01-10
公開日2014-10-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
2QMY
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Quinone Reductase 2 in complex with adrenochrome
分子名称: (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase, ...
著者Zhang, Z, Fu, Y, Buryanovskky, L.
登録日2007-07-17
公開日2008-06-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Quinone Reductase 2 regulates Catecholamine oxidation
To be Published
3UEY
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Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cdelta
分子名称: PHOSPHATE ION, Protein kinase C delta type, ZINC ION
著者Shanmugasundararaj, S, Stehle, T, Miller, K.W.
登録日2011-10-31
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.301 Å)
主引用文献Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
Biophys.J., 103, 2012
3UF6
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The crystal structure of a possible phosphate acetyl/butaryl transferase (from Listeria monocytogenes EGD-e) in complex with CoD (3'-dephosphocoenzyme A)
分子名称: DEPHOSPHO COENZYME A, Lmo1369 protein
著者Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2011-10-31
公開日2011-11-16
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of a possible phosphate acetyl/butaryl transferase (from Listeria monocytogenes EGD-e) in complex with CoD (3'-dephosphocoenzyme A)
To be Published
4OWV
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Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with anthranilate
分子名称: 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase, GLYCEROL, ...
著者Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S.
登録日2014-02-04
公開日2014-04-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
3UFR
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Structure of rat nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(((E)-5-(3-fluorophenyl)pent-4-en-1-yl)oxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4R)-4-{[(3E)-4-(3-fluorophenyl)but-3-en-1-yl]oxy}pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2011-11-01
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations.
J.Am.Chem.Soc., 134, 2012

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