PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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2ADI	Crystal structure of monoclonal anti-CD4 antibody Q425 in complex with Barium 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BARIUM ION, Q425 Fab Heavy chain, ... 著者 Zhou, T, Hamer, D.H, Hendrickson, W.A, Sattentau, Q.J, Kwong, P.D. 登録日 2005-07-20 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Interfacial metal and antibody recognition. Proc.Natl.Acad.Sci.Usa, 102, 2005
3V7A	Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle 分子名称: 5B18 heavy chain, 5B18 kappa chain, Capsid 著者 Hansman, G.S, Mclellan, J.S, Kwong, P.D. 登録日 2011-12-20 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.297 Å) 主引用文献 Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle. J.Virol., 86, 2012
3TYG	Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with a glycosylated engineered gp120 outer domain with miniV3 (eODmV3) 分子名称: Envelope glycoprotein gp160, PGT128 heavy chain, Ig gamma-1 chain C region, ... 著者 Pejchal, R, Huang, P.S, Schief, W.R, Stanfield, R.L, Wilson, I.A. 登録日 2011-09-25 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science, 334, 2011
4JO2	Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 Consensus A gp120 分子名称: CALCIUM ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R56 heavy chain, ... 著者 Pan, R.M, Kong, X.P. 登録日 2013-03-16 公開日 2013-07-31 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans. J.Virol., 87, 2013
7M1C	Crystal structure of the HCMV pentamer-specific antibody 1-32 分子名称: 1-32 Fab Heavy Chain, 1-32 Fab Light Chain 著者 Wrapp, D, McLellan, J.S. 登録日 2021-03-12 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8, 2022
7LYV	Crystal structure of the HCMV pentamer-specific antibody 1-103 分子名称: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain 著者 Wrapp, D, Jones, H.G, McLellan, J.S. 登録日 2021-03-08 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8, 2022
7LYW	Crystal structure of the HCMV pentamer-specific antibody 2-25 分子名称: 2-25 Fab Heavy Chain, 2-25 Fab Light Chain 著者 Wrapp, D, Mishra, A.K, McLellan, J.S. 登録日 2021-03-08 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8, 2022
8FE4	Structure of dengue virus (DENV2) in complex with prM13, an anti-PrM monoclonal antibody 分子名称: Envelope protein E, prM protein, prM13 Fab Heavy Chain, ... 著者 Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. 登録日 2022-12-05 公開日 2023-02-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (9.8 Å) 主引用文献 prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proc.Natl.Acad.Sci.USA, 120, 2023
8FE3	Structure of dengue virus (DENV2) in complex with prM12, an anti-PrM monoclonal antibody 分子名称: Envelope protein E, prM protein, prM12 Fab Heavy Chain, ... 著者 Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. 登録日 2022-12-05 公開日 2023-02-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (10.2 Å) 主引用文献 prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proc.Natl.Acad.Sci.USA, 120, 2023
3TWC	Crystal structure of broad and potent HIV-1 neutralizing antibody PGT127 in complex with Man9 分子名称: AMYLAMINE, PGT127 heavy chain, Ig gamma-1 chain C region, ... 著者 Pejchal, R, Wilson, I.A. 登録日 2011-09-21 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science, 334, 2011
1IVL	THE DE NOVO DESIGN OF AN ANTIBODY COMBINING SITE: CRYSTALLOGRAPHIC ANALYSIS OF THE VL DOMAIN CONFIRMS THE STRUCTURAL MODEL 分子名称: IGG-KAPPA M29B FV (LIGHT CHAIN), ISOPROPYL ALCOHOL 著者 Essen, L.-O, Skerra, A. 登録日 1994-05-04 公開日 1994-08-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 The de novo design of an antibody combining site. Crystallographic analysis of the VL domain confirms the structural model. J.Mol.Biol., 238, 1994
2ADJ	Crystal structure of monoclonal anti-CD4 antibody Q425 in complex with Calcium 分子名称: CALCIUM ION, Q425 Fab Heavy chain, Q425 Fab Light chain 著者 Zhou, T, Hamer, D.H, Hendrickson, W.A, Sattentau, Q.J, Kwong, P.D. 登録日 2005-07-20 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Interfacial metal and antibody recognition. Proc.Natl.Acad.Sci.Usa, 102, 2005
5ZUD	Fit R10 Fab coordinates into the cryo-EM of EV71 in complex with D6 分子名称: Capsid protein VP1, R10 ANTIBODY HEAVY CHAIN, R10 ANTIBODY LIGHT CHAIN, ... 著者 Wang, X, Zhu, L, Wang, N. 登録日 2018-05-07 公開日 2019-12-25 最終更新日 2021-01-06 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71. Mbio, 9, 2018
8K0D	Cryo-EM structure of conformation 2 of complex of Nipah virus attachment G with 1E5 neutralizing antibody 分子名称: Glycoprotein G, The heavy chain of 1E5, The light chain of 1E5 著者 Sun, M. 登録日 2023-07-08 公開日 2024-05-01 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 A potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer. Nat Commun, 15, 2024
8K0C	Cryo-EM structure of conformation 1 of complex of Nipah virus attachment glycoprotein G with 1E5 neutralizing antibody 分子名称: Glycoprotein G, Heavy chain of 1E5 Fab fragments, Light chain of 1E5 Fab fragments 著者 Sun, M.M. 登録日 2023-07-08 公開日 2024-05-01 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 A potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer. Nat Commun, 15, 2024
6RCQ	PfRH5-binding monoclonal antibody R5.011 分子名称: ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ... 著者 Alanine, D.W.G, Draper, S.J, Higgins, M.K. 登録日 2019-04-11 公開日 2019-06-26 最終更新日 2019-07-10 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
6RCS	PfRH5-binding monoclonal antibody R5.016 分子名称: ACETATE ION, R5.016 heavy chain, R5.016 light chain, ... 著者 Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K. 登録日 2019-04-11 公開日 2019-06-26 最終更新日 2019-08-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
4GQP	Structure based design of sub-nanomolar affinity anti-methamphetamine single chain antibodies. 分子名称: (2S)-N-methyl-1-phenylpropan-2-amine, Anti-METH scFv 著者 Thakkar, S, Varughese, K.I. 登録日 2012-08-23 公開日 2013-10-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering. Sci Rep, 4, 2014
2AGJ	Crystal Structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Yvo Fab, Heavy Chain, ... 著者 Ramsland, P.A, Terzyan, S.S, Cloud, G, Bourne, C.R, Farrugia, W, Tribbick, G, Geysen, H.M, Moomaw, C.R, Slaughter, C.A, Edmundson, A.B. 登録日 2005-07-27 公開日 2006-05-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody Biochem.J., 395, 2006
1NLD	FAB FRAGMENT OF A NEUTRALIZING ANTIBODY DIRECTED AGAINST AN EPITOPE OF GP41 FROM HIV-1 分子名称: FAB1583 著者 Davies, C, Beauchamp, J.C, Emery, D, Rawas, A, Muirhead, H. 登録日 1996-07-02 公開日 1996-12-23 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of the Fab fragment from a neutralizing monoclonal antibody directed against an epitope of gp41 from HIV-1. Acta Crystallogr.,Sect.D, 53, 1997
4QWW	Crystal structure of the Fab410-BfAChE complex 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... 著者 Bourne, Y, Renault, L, Marchot, P. 登録日 2014-07-17 公開日 2014-11-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site: EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL. J.Biol.Chem., 290, 2015
3NTC	Crystal structure of KD-247 Fab, an anti-V3 antibody that inhibits HIV-1 Entry 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Fab heavy chain, ... 著者 Sarafianos, S.G, Kirby, K.A. 登録日 2010-07-03 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247. Faseb J., 29, 2015
6Z3K	Structure of protective antibody 38-1-10A Fab 分子名称: 1,2-ETHANEDIOL, Heavy chain, Light Chain 著者 Zhou, D, Fry, E.E, Ren, J, Stuart, D.I. 登録日 2020-05-20 公開日 2020-09-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71. Nat Commun, 11, 2020
3OJD	Anti-Indolicidin monoclonal antibody V2D2 (Fab fragment) 分子名称: Fab V2D2 著者 Lomash, S, Salunke, D.M. 登録日 2010-08-22 公開日 2010-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An antibody as surrogate receptor reveals determinants of activity of an innate immune peptide antibiotic J.Biol.Chem., 285, 2010
7R6X	SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2E12 Fab, S309 Fab, and S304 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Monoclonal antibody S2E12 Fab heavy chain, ... 著者 Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M. 登録日 2021-06-23 公開日 2021-07-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape. Nature, 597, 2021

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