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4B9W
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Structure of extended Tudor domain TD3 from mouse TDRD1 in complex with MILI peptide containing dimethylarginine 45.
分子名称: GLYCEROL, PIWI-LIKE PROTEIN 2, TUDOR DOMAIN-CONTAINING PROTEIN 1
著者Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S.
登録日2012-09-08
公開日2012-10-17
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors.
Rna, 18, 2012
4B3E
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Structure of copper-zinc superoxide dismutase complexed with bicarbonate.
分子名称: CARBONATE ION, COPPER (II) ION, SULFATE ION, ...
著者Strange, R.W, Hough, M.A, Antonyuk, S.V, Hasnain, S.S.
登録日2012-07-23
公開日2012-09-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase.
Plos One, 7, 2012
4B75
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Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
分子名称: (2S)-4-amino-N-[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propyl]-4-oxobutan-2-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3
著者Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
4BC4
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Crystal structure of human D-xylulokinase in complex with D-xylulose
分子名称: 1,2-ETHANEDIOL, D-XYLULOSE, XYLULOSE KINASE
著者Bunker, R.D, Loomes, K.M, Baker, E.N.
登録日2012-10-01
公開日2012-11-28
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism
J.Biol.Chem., 288, 2013
417D
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A THYMINE-LIKE BASE ANALOGUE FORMS WOBBLE PAIRS WITH ADENINE
分子名称: DNA (5'-D(*CP*AP*CP*GP*(C46)P*G)-3')
著者Lin, P.K.T, Schuerman, M.H, Moore, G.S, Van Meervelt, L, Loakes, D, Brown, D.M, Moore, M.H.
登録日1998-07-15
公開日1998-09-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A thymine-like base analogue forms wobble pairs with adenine in a Z-DNA duplex.
J.Mol.Biol., 282, 1998
4A7V
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BU of 4a7v by Molmil
Structure of human I113T SOD1 mutant complexed with dopamine in the p21 space group
分子名称: COPPER (II) ION, L-DOPAMINE, SULFATE ION, ...
著者Wright, G.S.A, Antonyuk, S.V, Kershaw, N.M, Strange, R.W, Hasnain, S.S.
登録日2011-11-14
公開日2012-11-28
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
4A3B
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RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid
分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
著者Cheung, A.C.M, Sainsbury, S, Cramer, P.
登録日2011-09-30
公開日2011-12-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A4E
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Solution structure of SMN Tudor domain in complex with symmetrically dimethylated arginine
分子名称: N3, N4-DIMETHYLARGININE, SURVIVAL MOTOR NEURON PROTEIN
著者Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M.
登録日2011-10-12
公開日2011-11-30
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins
Nat.Struct.Mol.Biol., 18, 2011
4A53
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Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6
分子名称: EDC3
著者Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R.
登録日2011-10-24
公開日2012-02-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex.
Embo J., 31, 2011
4APD
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BU of 4apd by Molmil
Liraglutide
分子名称: LIRAGLUTIDE, N-hexadecanoyl-L-glutamic acid
著者Ludvigsen, S, Steensgaard, D.B, Thomsen, J.K, Strauss, H, Normann, M.
登録日2012-04-02
公開日2013-07-10
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Liraglutide
To be Published
4A4H
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BU of 4a4h by Molmil
Solution structure of SPF30 Tudor domain in complex with asymmetrically dimethylated arginine
分子名称: NG,NG-DIMETHYL-L-ARGININE, SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30
著者Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M.
登録日2011-10-12
公開日2011-11-30
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins
Nat.Struct.Mol.Biol., 18, 2011
4A86
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Crystal Structure of Major Birch Pollen Allergen Bet v 1 a in ternary complex with kinetin and 8-Anilinonaphthalene-1-sulfonate (ANS)
分子名称: 8-ANILINO-1-NAPHTHALENE SULFONATE, MAJOR POLLEN ALLERGEN BET V 1-A, N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE, ...
著者Kofler, S, Brandstetter, H.
登録日2011-11-18
公開日2012-05-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1.
J.Mol.Biol., 422, 2012
4A7D
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BU of 4a7d by Molmil
X-ray crystal structure of HEWL flash-cooled at high pressure
分子名称: CHLORIDE ION, LYSOZYME C, SODIUM ION
著者Burkhardt, A, Warmer, M, Panneerselvam, S, Wagner, A, Reimer, R, Hohenberg, H, Meents, A.
登録日2011-11-14
公開日2011-11-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.497 Å)
主引用文献Fast High-Pressure Freezing of Protein Crystals in Their Mother Liquor
Acta Crystallogr.,Sect.F, 68, 2012
4A84
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Crystal Structure of Major Birch Pollen Allergen Bet v 1 a F30V mutant in complex with deoxycholate.
分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, MAJOR POLLEN ALLERGEN BET V 1-A, ...
著者Kofler, S, Brandstetter, H.
登録日2011-11-18
公開日2012-05-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1.
J.Mol.Biol., 422, 2012
4B73
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Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
分子名称: (2S)-4-amino-N-[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propyl]-4-oxobutan-2-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3
著者Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function.
Nat.Chem.Biol., 8, 2012
4BC5
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Crystal structure of human D-xylulokinase in complex with inhibitor 5- deoxy-5-fluoro-D-xylulose
分子名称: 1,2-ETHANEDIOL, 5-deoxy-5-fluoro-D-xylulose, XYLULOSE KINASE
著者Bunker, R.D, Loomes, K.M, Baker, E.N.
登録日2012-10-01
公開日2012-11-28
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism
J.Biol.Chem., 288, 2013
4A7F
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Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 3)
分子名称: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S.
登録日2011-11-14
公開日2012-08-01
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Structure of the Rigor Actin-Tropomyosin-Myosin Complex.
Cell(Cambridge,Mass.), 150, 2012
4A93
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RNA Polymerase II elongation complex containing a CPD Lesion
分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ...
著者Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M.
登録日2011-11-23
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46, 2012
4AOJ
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Human TrkA in complex with the inhibitor AZ-23
分子名称: 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR, ZINC ION
著者Wang, T, Lamb, M.L, Block, M.H, Davies, A.M, Han, Y, Hoffmann, E, Ioannidis, S, Josey, J.A, Liu, Z, Lyne, P.D, MacIntyre, T, Mohr, P.J, Omer, C.A, Sjogren, T, Thress, K, Wang, B, Wang, H, Yu, D, Zhang, H.
登録日2012-03-28
公開日2012-08-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Discovery of Disubstituted Imidazo[4,5-B]Pyridines and Purines as Potent Trka Inhibitors
Acs Med.Chem.Lett., 3, 2012
4AQ5
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Gating movement in acetylcholine receptor analysed by time-resolved electron cryo-microscopy (closed class)
分子名称: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
著者Unwin, N, Fujiyoshi, Y.
登録日2012-04-12
公開日2012-08-01
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Gating Movement of Acetylcholine Receptor Caught by Plunge-Freezing.
J.Mol.Biol., 422, 2012
4A4G
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Solution structure of SMN Tudor domain in complex with asymmetrically dimethylated arginine
分子名称: NG,NG-DIMETHYL-L-ARGININE, SURVIVAL MOTOR NEURON PROTEIN
著者Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M.
登録日2011-10-12
公開日2011-11-30
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins
Nat.Struct.Mol.Biol., 18, 2011
430D
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BU of 430d by Molmil
STRUCTURE OF SARCIN/RICIN LOOP FROM RAT 28S RRNA
分子名称: MAGNESIUM ION, SARCIN/RICIN LOOP FROM RAT 28S R-RNA
著者Correll, C.C, Munishkin, A, Chan, Y.L, Ren, Z, Wool, I.G, Steitz, T.A.
登録日1998-10-04
公開日1998-10-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the ribosomal RNA domain essential for binding elongation factors.
Proc.Natl.Acad.Sci.USA, 95, 1998
4A8A
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Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme
分子名称: LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
著者Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R.
登録日2011-11-20
公開日2011-12-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (14.2 Å)
主引用文献Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A83
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Crystal Structure of Major Birch Pollen Allergen Bet v 1 a in complex with deoxycholate.
分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, MAJOR POLLEN ALLERGEN BET V 1-A, ...
著者Kofler, S, Brandstetter, H.
登録日2011-11-18
公開日2012-05-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1.
J.Mol.Biol., 422, 2012
4A7L
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Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 1)
分子名称: ACTIN, ALPHA SKELETON MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S.
登録日2011-11-14
公開日2012-08-01
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Structure of the Rigor Actin-Tropomyosin-Myosin Complex.
Cell(Cambridge,Mass.), 150, 2012

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