PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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6H7F	Crystal structure of BauA, the Ferric preacinetobactin receptor from Acinetobacter baumannii in complex with Fe3+-Preacinetobactin-acinetobactin 分子名称: (4~{S},5~{R})-2-[2,3-bis(oxidanyl)phenyl]-~{N}-[2-(1~{H}-imidazol-4-yl)ethyl]-5-methyl-~{N}-oxidanyl-4,5-dihydro-1,3-oxazole-4-carboxamide, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, ... 著者 Moynie, L, Naismith, J.H. 登録日 2018-07-31 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogenAcinetobacter baumannii. Elife, 7, 2018
6H7A	Structure of Leishmania PABP1 (domain J). 分子名称: PABP1 domain J 著者 Cameron, A.D, Firczuk, H, dos Santos Rodrigues, F.H, McCarthy, J.E.G. 登録日 2018-07-31 公開日 2018-12-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs. Nucleic Acids Res., 47, 2019
6APA	Crystal structure of TEM1 beta-lactamase mutant I263A 分子名称: Beta-lactamase TEM 著者 Roose, B.W, Dmochowski, I.J. 登録日 2017-08-17 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 A Structural Basis for129Xe Hyper-CEST Signal in TEM-1 beta-Lactamase. Chemphyschem, 20, 2019
6H54	CRYSTAL STRUCTURE OF BOVINE HSC70(AA1-554)E213A/D214A IN COMPLEX WITH INHIBITOR VER155008 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, GLYCEROL, ... 著者 Plank, C, Zehe, M, Grimm, C, Sotriffer, C. 登録日 2018-07-23 公開日 2019-08-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
6GF2	The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome 分子名称: Ubiquitin D 著者 Aichem, A, Anders, S, Catone, N, Roessler, P, Stotz, S, Berg, A, Schwab, R, Scheuermann, S, Bialas, J, Schmidtke, G, Peter, C, Groettrup, M, Wiesner, S. 登録日 2018-04-29 公開日 2018-08-08 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation. Nat Commun, 9, 2018
6GFT	Antinociceptive evaluation of cyriotoxin-1a, the first toxin purified from Cyriopagopus schioedtei spider venom 分子名称: cyriotoxin-1a 著者 Kurz, M. 登録日 2018-05-02 公開日 2019-03-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 From identification to functional characterization of cyriotoxin-1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei. Br.J.Pharmacol., 176, 2019
6H8O	Crystal structure of the Master-Rep protein nuclease domain from the Faba Bean Necrotic Yellows Virus 分子名称: Replication-associated protein, SULFATE ION 著者 Moncalian, G, Gonzalez-Montes, L. 登録日 2018-08-02 公開日 2018-08-22 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Crystal structure of the Master-Rep protein nuclease domain from the Faba Bean Necrotic Yellows Virus To Be Published
6H8S	CRYSTAL STRUCTURE OF THE MOUSE PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND BI-0314 分子名称: 1-[3-piperidin-4-yl-5-(trifluoromethyl)phenyl]guanidine, Tyrosine-protein phosphatase non-receptor type 5 著者 Fiegen, D, Schnapp, G. 登録日 2018-08-03 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.771 Å) 主引用文献 Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule. J. Med. Chem., 62, 2019
6H7V	Crystal structure of BauA, the Ferric preacinetobactin receptor from Acinetobacter baumannii 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, Ligand-gated channel protein 著者 Moynie, L, Naismith, J.H. 登録日 2018-07-31 公開日 2018-10-10 最終更新日 2019-01-16 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogenAcinetobacter baumannii. Elife, 7, 2018
6H90	K145A variant of beta-phosphoglucomutase from Lactococcus lactis inhibited by beryllium trifluoride to 1.3 A. 分子名称: 1,2-ETHANEDIOL, BERYLLIUM TRIFLUORIDE ION, Beta-phosphoglucomutase, ... 著者 Robertson, A.J, Bisson, C, Waltho, J.P. 登録日 2018-08-03 公開日 2020-08-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Transition state of phospho-enzyme hydrolysis in beta-phosphoglucomutase. To Be Published
6HB9	Crystal structure of the GABARAP in complex with the UBA5 LIR motif 分子名称: Gamma-aminobutyric acid receptor-associated protein 著者 Huber, J, Rogov, V, Akutsu, M. 登録日 2018-08-10 公開日 2019-05-01 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. Autophagy, 16, 2020
6DCN	Bcl-xL complex with Beclin 1 BH3 domain T108pThr 分子名称: BCL-xl protein, Beclin-1 著者 Lee, E.F, Smith, B.J, Smith, N.A, Yao, S, Fairlie, W.D. 登録日 2018-05-07 公開日 2018-05-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.444 Å) 主引用文献 Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1. Autophagy, 15, 2019
6DGK	Crystal Structure of the Non-Structural Protein 1 (NS1) effector domain W187A mutant from the A/Brevig Mission/1/1918 (H1N1) strain of Influenza A Virus 分子名称: Non-structural protein 1 著者 Kleinpeter, A.B, Green, T.J, Petit, C.M. 登録日 2018-05-17 公開日 2018-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds. J. Biol. Chem., 293, 2018
6DAD	1.65 Angstrom crystal structure of the N97I Ca/CaM:CaV1.2 IQ domain complex 分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Wang, K, Van Petegem, F. 登録日 2018-05-01 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DF9	Kaiso (ZBTB33) E535Q zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) 分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... 著者 Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. 登録日 2018-05-14 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.319 Å) 主引用文献 A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences. Biochemistry, 2020
6DJW	Crystal Structure of pParkin (REP and RING2 deleted)-pUb-UbcH7 complex 分子名称: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... 著者 Sauve, V, Sung, G, Trempe, J.F, Gehring, K. 登録日 2018-05-26 公開日 2018-07-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.801 Å) 主引用文献 Mechanism of parkin activation by phosphorylation. Nat. Struct. Mol. Biol., 25, 2018
6DL0	Crystal structure of pohlianin C, an orbitide from Jatropha pohliana 分子名称: pohlianin C 著者 Wang, C.K, King, G.J, Ramalho, S.D. 登録日 2018-05-31 公開日 2018-11-07 最終更新日 2023-07-26 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species. J. Nat. Prod., 81, 2018
6DCO	Bcl-xL complex with Beclin 1 BH3 domain T108D 分子名称: Bcl-2-like protein 1,Bcl-2-like protein 1, Beclin-1, CHLORIDE ION 著者 Lee, E.F, Smith, B.J, Smith, N.A, Yao, S, Fairlie, W.D. 登録日 2018-05-07 公開日 2018-05-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.198 Å) 主引用文献 Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1. Autophagy, 15, 2019
6DN6	SPRY domain-containing SOCS box protein 2 complexed with INNN(ABU) cyclic peptide inhibitor 分子名称: INNN(ABU) cyclic peptide inhibitor, SPRY domain-containing SOCS box protein 2 著者 Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S. 登録日 2018-06-06 公開日 2019-04-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem. Biol., 13, 2018
6DHA	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Hydroxy Pioglitazone (M-IV) 分子名称: Hydroxy Pioglitazone (M-IV), Peroxisome proliferator-activated receptor gamma, nonanoic acid 著者 Shang, J, Mosure, S.A, Kojetin, D.J. 登録日 2018-05-18 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPAR gamma Drug Pioglitazone. J. Med. Chem., 62, 2019
6DGL	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Darglitazone 分子名称: (5Z)-5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl}methylidene)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma 著者 Shang, J, Kojetin, D.J. 登録日 2018-05-17 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Quantitative structural assessment of graded receptor agonism. Proc.Natl.Acad.Sci.USA, 116, 2019
6DKZ	Racemic structure of ribifolin, an orbitide from Jatropha ribifolia 分子名称: ribifolin 著者 Wang, C.K, King, G.J, Ramalho, S.D. 登録日 2018-05-31 公開日 2018-11-14 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (0.99 Å) 主引用文献 Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species. J. Nat. Prod., 81, 2018
6DNS	Endo-fucoidan hydrolase MfFcnA9 from glycoside hydrolase family 107 分子名称: 1,2-ETHANEDIOL, Alpha-1,4-endofucoidanase, CALCIUM ION 著者 Vickers, C, Abe, K, Salama-Alber, O, Boraston, A.B. 登録日 2018-06-07 公開日 2018-10-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to alpha-l-fucosidases from GH29. J. Biol. Chem., 293, 2018
6DSL	Consensus engineered intein (Cat) with atypical split site 分子名称: Consensus engineered intein CatC, Consensus engineered intein CatN 著者 Sekar, G, Stevens, A.J, Muir, T.W, Cowburn, D. 登録日 2018-06-14 公開日 2018-09-19 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 An Atypical Mechanism of Split Intein Molecular Recognition and Folding. J. Am. Chem. Soc., 140, 2018
6DAH	2.5 Angstrom crystal structure of the N97S CaM mutant 分子名称: CALCIUM ION, Calmodulin-1 著者 Wang, K, Van Petegem, F. 登録日 2018-05-01 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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