PDB: 2596 件ウェブページステータス検索Chemie searchBIRD

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1TTU	Crystal Structure of CSL bound to DNA 分子名称: 1,2-ETHANEDIOL, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3', ... 著者 Kovall, R.A, Hendrickson, W.A. 登録日 2004-06-23 公開日 2004-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA Embo J., 23, 2004
5VTB	Crystal structure of RBBP4 bound to BCL11a peptide 分子名称: B-cell lymphoma/leukemia 11A, GLYCEROL, Histone-binding protein RBBP4 著者 Meagher, J.L, Stuckey, J.A. 登録日 2017-05-16 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes. J. Biol. Chem., 293, 2018
5YP6	RORgamma (263-509) complexed with SRC2 and Compound 6 分子名称: N-[3'-cyano-4'-(2-methylpropyl)-2-(trifluoromethyl)biphenyl-4-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, SRC2 著者 Gao, M, Cai, W. 登録日 2017-11-01 公開日 2018-02-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 From ROR gamma t Agonist to Two Types of ROR gamma t Inverse Agonists ACS Med Chem Lett, 9, 2018
3NSQ	Crystal structure of tetrameric RXRalpha-LBD complexed with antagonist danthron 分子名称: 1,8-dihydroxyanthracene-9,10-dione, Retinoid X receptor, alpha 著者 Zhang, H, Hu, T, Li, L, Zhou, R, Chen, L, Hu, L, Jiang, H, Shen, X. 登録日 2010-07-02 公開日 2010-11-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. J.Biol.Chem., 286, 2011
5YP5	Crystal structure of RORgamma complexed with SRC2 and compound 5d 分子名称: 2-[4-(ethylsulfonyl)phenyl]-N-{5-[2-(2-methylpropyl)benzoyl]-4-phenyl-1,3-thiazol-2-yl}acetamide, Nuclear receptor ROR-gamma, SRC2-2 peptide 著者 Gao, M, Cai, W, Chunwa, C. 登録日 2017-11-01 公開日 2018-04-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 From ROR gamma t Agonist to Two Types of ROR gamma t Inverse Agonists ACS Med Chem Lett, 9, 2018
3NSP	Crystal structure of tetrameric RXRalpha-LBD 分子名称: Retinoid X receptor, alpha 著者 Zhang, H, Hu, T, Li, L, Zhou, R, Chen, L, Hu, L, Jiang, H, Shen, X. 登録日 2010-07-02 公開日 2010-11-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. J.Biol.Chem., 286, 2011
6AN1	Crystal structure of the complex between PPARgamma LBD and the ligand AM-879 分子名称: 4-({2-[(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)methyl]phenoxy}methyl)benzoic acid, Peroxisome proliferator-activated receptor gamma 著者 Veras, H, Figueira, A.C, le Maire, A. 登録日 2017-08-11 公開日 2018-02-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.687 Å) 主引用文献 Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties. Front Endocrinol (Lausanne), 9, 2018
6C9L	MEF2B Apo Protein Structure 分子名称: Myocyte-specific enhancer factor 2B 著者 Lei, X, Chen, L. 登録日 2018-01-26 公開日 2018-02-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of Apo MEF2B Reveals New Insights in DNA Binding and Cofactor Interaction. Biochemistry, 57, 2018
6C5Q	PPARg LBD bound to SR10171 分子名称: 2-{3-[(5-{[(1S)-1-(4-tert-butylphenyl)ethyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]phenoxy}-2-methylpropanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Bruning, J.B, Frkic, R.L. 登録日 2018-01-16 公開日 2018-08-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.404 Å) 主引用文献 PPAR gamma in Complex with an Antagonist and Inverse Agonist: a Tumble and Trap Mechanism of the Activation Helix. iScience, 5, 2018
6C5T	PPARg LBD bound to SR11023 分子名称: 2-{4-[(5-{[(1R)-1-(3-cyclopropylphenyl)ethyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]phenyl}-2-methylpropanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Bruning, J.B, Frkic, R.L, Griffin, P.R. 登録日 2018-01-16 公開日 2018-08-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 PPAR gamma in Complex with an Antagonist and Inverse Agonist: a Tumble and Trap Mechanism of the Activation Helix. iScience, 5, 2018
3HS2	Crystal structure of PHD truncated to residue 57 in an orthorhombic space group 分子名称: Prevent host death protein, SULFATE ION 著者 Garcia-Pino, A, Loris, R. 登録日 2009-06-10 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity. Cell(Cambridge,Mass.), 142, 2010
1RZS	Solution structure of P22 Cro 分子名称: Regulatory protein cro 著者 Newlove, T, Konieczka, J.H, Cordes, M.H. 登録日 2003-12-28 公開日 2004-06-01 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Secondary structure switching in Cro protein evolution. STRUCTURE, 12, 2004
4DMA	Crystal structure of ERa LBD in complex with RU100132 分子名称: 2'-bromo-6'-(furan-3-yl)-4'-(hydroxymethyl)biphenyl-4-ol, Estrogen receptor, Nuclear receptor coactivator 1 著者 Osz, J, Brelivet, Y, Peluso-Iltis, C, Cura, V, Eiler, S, Ruff, M, Bourguet, W, Rochel, N, Moras, D. 登録日 2012-02-07 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors. Proc.Natl.Acad.Sci.USA, 109, 2012
1HQO	CRYSTAL STRUCTURE OF THE NITROGEN REGULATION FRAGMENT OF THE YEAST PRION PROTEIN URE2P 分子名称: URE2 PROTEIN 著者 Umland, T.C, Taylor, K.L, Rhee, S, Wickner, R.B, Davies, D.R. 登録日 2000-12-18 公開日 2001-02-14 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p. Proc.Natl.Acad.Sci.USA, 98, 2001
4QK4	Crystal structure of human nuclear receptor sf-1 (nr5a1) bound to pip2 at 2.8 a resolution 分子名称: (2S)-3-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1,2-ETHANEDIOL, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2014-06-05 公開日 2014-07-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1. Proc.Natl.Acad.Sci.USA, 111, 2014
4QJR	Crystal structure of human nuclear receptor sf-1 (nr5a1) bound to its hormone pip3 at 2.4 a resolution 分子名称: (2S)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dihexadecanoate, ACETATE ION, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2014-06-04 公開日 2014-07-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1. Proc.Natl.Acad.Sci.USA, 111, 2014
5DGE	Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. 登録日 2015-08-27 公開日 2017-01-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
5DAT	Complex of yeast 80S ribosome with hypusine-containing eIF5A 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. 登録日 2015-08-20 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
4V88	The structure of the eukaryotic ribosome at 3.0 A resolution. 分子名称: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ... 著者 Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M. 登録日 2011-10-11 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the eukaryotic ribosome at 3.0 angstrom resolution. Science, 334, 2011
4V54	Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome recycling factor (RRF). 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. 登録日 2007-06-16 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
4V4Q	Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D. 登録日 2005-08-30 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.46 Å) 主引用文献 Structures of the bacterial ribosome at 3.5 A resolution. Science, 310, 2005
6HHQ	Crystal structure of compound C45 bound to the yeast 80S ribosome 分子名称: (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Pellegrino, S, Vanderwal, C.D, Yusupov, M. 登録日 2018-08-28 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.10000038 Å) 主引用文献 Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47, 2019
5NDV	Crystal structure of Paromomycin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-03-09 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OBM	Crystal structure of Gentamicin bound to the yeast 80S ribosome 分子名称: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-06-28 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5ON6	Crystal structure of haemanthamine bound to the 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Pellegrino, S, Meyer, M, Yusupova, G, Yusupov, M. 登録日 2017-08-03 公開日 2018-02-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.10000229 Å) 主引用文献 The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth. Structure, 26, 2018

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