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2XMQ
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Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor
分子名称: ACETATE ION, PROTEIN NDRG2
著者Hwang, J, Kim, Y, Lee, H, Kim, M.H.
登録日2010-07-29
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor.
J.Biol.Chem., 286, 2011
3DVT
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BU of 3dvt by Molmil
Biochemical and structural characterization of the PAK1- LC8 interaction
分子名称: Dynein light chain 1, cytoplasmic
著者LIghtcap, C.M, Williams, J.C.
登録日2008-07-20
公開日2009-05-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
3DVH
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LC8 Point mutant K36P
分子名称: Dynein light chain 1, cytoplasmic
著者Lightcap, C.M, Williams, J.C.
登録日2008-07-18
公開日2009-01-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
3DVP
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Pak1 peptide bound LC8
分子名称: Dynein light chain 1, cytoplasmic, P21 activated Kinase peptide
著者Lightcap, C.M, Williams, J.C.
登録日2008-07-18
公開日2009-01-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical and structural characterization of the Pak1-LC8 interaction.
J.Biol.Chem., 283, 2008
3B13
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Crystal structure of the DHR-2 domain of DOCK2 in complex with Rac1 (T17N mutant)
分子名称: Dedicator of cytokinesis protein 2, Ras-related C3 botulinum toxin substrate 1
著者Hanawa-Suetsugu, K, Kukimoto-Niino, M, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S.
登録日2011-06-24
公開日2012-03-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.006 Å)
主引用文献Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc.Natl.Acad.Sci.USA, 109, 2012
4JMO
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Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
分子名称: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
著者Hoh, F, Rouhana, J.
登録日2013-03-14
公開日2013-10-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4JQ0
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Voltage-gated sodium channel 1.5 C-terminal domain in complex with FGF12B and Ca2+/calmodulin
分子名称: CALCIUM ION, Calmodulin, Fibroblast growth factor 12, ...
著者Wang, C, Chung, B.C, Yan, H, Wang, H.G, Lee, S.Y, Pitt, G.S.
登録日2013-03-19
公開日2014-05-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.84 Å)
主引用文献Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.
Nat Commun, 5, 2014
4MX9
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CDPK1 from Neospora caninum in complex with inhibitor UW1294
分子名称: 3-(6-ethoxynaphthalen-2-yl)-1-[(1-methylpiperidin-4-yl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-like domain protein kinase isoenzyme gamma, related
著者Merritt, E.A.
登録日2013-09-26
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Neospora caninum Calcium-Dependent Protein Kinase 1 Is an Effective Drug Target for Neosporosis Therapy.
Plos One, 9, 2014
2OD8
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Structure of a peptide derived from Cdc9 bound to PCNA
分子名称: DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen
著者Chapados, B.R, Tainer, J.A.
登録日2006-12-21
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.
Nucleic Acids Res., 35, 2007
1L7Z
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Crystal structure of Ca2+/Calmodulin complexed with myristoylated CAP-23/NAP-22 peptide
分子名称: CALCIUM ION, CALMODULIN, CAP-23/NAP-22, ...
著者Matsubara, M, Nakatsu, T, Yamauchi, E, Kato, H, Taniguchi, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-03-18
公開日2003-09-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a myristoylated CAP-23/NAP-22 N-terminal domain complexed with Ca2+/calmodulin
EMBO J., 23, 2004
5ZB3
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BU of 5zb3 by Molmil
Dimeric crystal structure of ORF57 from KSHV
分子名称: ORF57, ZINC ION
著者Gao, Z.Q, Yuan, F, Dong, Y.H, Lan, K.
登録日2018-02-09
公開日2018-08-08
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.506 Å)
主引用文献The crystal structure of KSHV ORF57 reveals dimeric active sites important for protein stability and function.
PLoS Pathog., 14, 2018
4NAM
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1.7A structure of 5-Fluoro Tryptophan Labeled Protective Antigen (W206Y)
分子名称: CALCIUM ION, Protective antigen
著者Lovell, S, Battaile, K.P, Chadegani, F, Mulangi, V, Miyagi, M, Bann, J.G.
登録日2013-10-22
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献(19)F nuclear magnetic resonance and crystallographic studies of 5-fluorotryptophan-labeled anthrax protective antigen and effects of the receptor on stability.
Biochemistry, 53, 2014
3C6L
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Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR 2W20
分子名称: 3K peptide, Linker,and H-2 class II histocompatibility antigen (A beta chain), CALCIUM ION, ...
著者Dai, S.
登録日2008-02-04
公開日2008-04-29
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Immunity, 28, 2008
3C1Q
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The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, CHLORIDE ION, ...
著者Abendroth, J, Mitchell, D.D, Korotkov, K.V, Kreeger, A, Hol, W.G.J.
登録日2008-01-24
公開日2009-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae
J.Struct.Biol., 166, 2009
4N0H
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Crystal structure of S. cerevisiae mitochondrial GatFAB
分子名称: Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glutamyl-tRNA(Gln) amidotransferase subunit B, ...
著者Araiso, Y, Ishitani, R, Nureki, O.
登録日2013-10-02
公開日2014-04-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases
Nucleic Acids Res., 42, 2014
3C2X
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Crystal structure of peptidoglycan recognition protein at 1.8A resolution
分子名称: GLYCEROL, L(+)-TARTARIC ACID, Peptidoglycan recognition protein, ...
著者Sharma, P, Singh, N, Sinha, M, Sharma, S, Perbandt, M, Betzel, C, Kaur, P, Srinivasan, A, Singh, T.P.
登録日2008-01-26
公開日2008-03-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Crystal structure of the peptidoglycan recognition protein at 1.8 A resolution reveals dual strategy to combat infection through two independent functional homodimers
J.Mol.Biol., 378, 2008
3HTS
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HEAT SHOCK TRANSCRIPTION FACTOR/DNA COMPLEX
分子名称: 5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3', GLYCEROL, HEAT SHOCK TRANSCRIPTION FACTOR
著者Littlefield, O, Nelson, H.C.M.
登録日1998-11-16
公開日1999-04-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A new use for the 'wing' of the 'winged' helix-turn-helix motif in the HSF-DNA cocrystal.
Nat.Struct.Biol., 6, 1999
3C5Z
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Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR B3K506
分子名称: 3K peptide, Linker, and H-2 class II histocompatibility antigen (A beta chain), ...
著者Dai, S, Kappler, J.
登録日2008-02-01
公開日2008-04-29
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Immunity, 28, 2008
2PVS
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BU of 2pvs by Molmil
Structure of human pancreatic lipase related protein 2 mutant N336Q
分子名称: CALCIUM ION, Pancreatic lipase-related protein 2, SULFATE ION
著者Spinelli, S, Eydoux, C, Carriere, F, Cambillau, C.
登録日2007-05-10
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation.
Biochemistry, 47, 2008
4N8W
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cathepsin K - chondroitin sulfate complex
分子名称: 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Cathepsin K
著者Aguda, A.H, Nguyen, N.T, Bromme, D, Brayer, G.D.
登録日2013-10-18
公開日2014-11-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural basis of collagen fiber degradation by cathepsin K.
Proc.Natl.Acad.Sci.USA, 111, 2014
3JUY
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Crystal Structure of a 3B3 Variant, a Broadly Neutralizing HIV-1 scFv Antibody
分子名称: 3B3 single chain variant HIV-1 antibody
著者Clark, K.R, Walsh, S.T.
登録日2009-09-15
公開日2009-12-08
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a 3B3 variant-A broadly neutralizing HIV-1 scFv antibody.
Protein Sci., 18, 2009
3G6W
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Asymetric GTP bound structure of UPRTase from Sulfolobus solfataricus containing PRPP-mg2+ in half of the active sites and R5P and PPi in the other half
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 5-O-phosphono-alpha-D-ribofuranose, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Kadziola, A, Christoffersen, S.
登録日2009-02-09
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus
J.Mol.Biol., 393, 2009
4JXH
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Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH 8.5
分子名称: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide, PHOSPHATE ION
著者Hoh, F, Rouhana, J.
登録日2013-03-28
公開日2013-10-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
2PHO
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Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution
分子名称: Arginase-1, HYDRAZINECARBOTHIOAMIDE, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2007-04-11
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster.
J.Am.Chem.Soc., 129, 2007
1LJW
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Crystal Structure of Human Carbonmonoxy Hemoglobin at 2.16 A: A Snapshot of the Allosteric Transition
分子名称: CARBON MONOXIDE, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Safo, M.K, Burnett, J.C, Musayev, F.N, Nokuri, S, Abraham, D.J.
登録日2002-04-22
公開日2002-05-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structure of human carbonmonoxyhemoglobin at 2.16 A: a snapshot of the allosteric transition.
Acta Crystallogr.,Sect.D, 58, 2002

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