8W6P
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![BU of 8w6p by Molmil](/molmil-images/mine/8w6p) | Crystal structure of dimeric murine SMPDL3A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ... | 著者 | Zhang, C, Liu, P, Fan, S, Hou, Y. | 登録日 | 2023-08-29 | 公開日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing. Immunity, 56, 2023
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8W6R
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![BU of 8w6r by Molmil](/molmil-images/mine/8w6r) | murine SMPDL3A bound to sulfate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ... | 著者 | Zhang, C, Liu, P, Fan, S. | 登録日 | 2023-08-29 | 公開日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing. Immunity, 56, 2023
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5NAN
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![BU of 5nan by Molmil](/molmil-images/mine/5nan) | Crystal Structure of human IL-17AF in complex with human IL-17RA | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-galactopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | 著者 | Rondeau, J.-M, Goepfert, A. | 登録日 | 2017-02-28 | 公開日 | 2017-09-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties. Sci Rep, 7, 2017
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6PXU
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![BU of 6pxu by Molmil](/molmil-images/mine/6pxu) | Crystal structure of human GalNAc-T12 bound to a diglycosylated peptide, Mn2+, and UDP | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, GAGATGAGAGYYITPRTGAGA, ... | 著者 | Samara, N.L, Fernandez, A.J. | 登録日 | 2019-07-27 | 公開日 | 2019-09-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.007 Å) | 主引用文献 | The structure of the colorectal cancer-associated enzyme GalNAc-T12 reveals how nonconserved residues dictate its function. Proc.Natl.Acad.Sci.USA, 116, 2019
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6TMR
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![BU of 6tmr by Molmil](/molmil-images/mine/6tmr) | Mokola virus glycoprotein, monomeric post-fusion conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, TERBIUM(III) ION | 著者 | Belot, L, Roche, S, Legrand, P, Gaudin, Y, Albertini, A. | 登録日 | 2019-12-05 | 公開日 | 2020-02-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.893 Å) | 主引用文献 | Crystal structure of Mokola virus glycoprotein in its post-fusion conformation. Plos Pathog., 16, 2020
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7R85
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![BU of 7r85 by Molmil](/molmil-images/mine/7r85) | |
6T2H
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![BU of 6t2h by Molmil](/molmil-images/mine/6t2h) | Furano[2,3-d]prymidine amides as Notum inhibitors | 分子名称: | 1,2-ETHANEDIOL, 2-[[(4~{S})-5-chloranyl-6-methyl-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-4-yl]sulfanyl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Y, Jones, E.Y. | 登録日 | 2019-10-08 | 公開日 | 2020-01-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
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7R84
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5I8R
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![BU of 5i8r by Molmil](/molmil-images/mine/5i8r) | aSMase with zinc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sphingomyelin phosphodiesterase, ... | 著者 | Zhou, Y.F, Wei, R.R. | 登録日 | 2016-02-19 | 公開日 | 2016-09-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.646 Å) | 主引用文献 | Human acid sphingomyelinase structures provide insight to molecular basis of Niemann-Pick disease. Nat Commun, 7, 2016
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7BZ0
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![BU of 7bz0 by Molmil](/molmil-images/mine/7bz0) | complex structure of alginate lyase AlyF-OU02 with G6 | 分子名称: | Alginate lyase AlyF-OU02, CALCIUM ION, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid | 著者 | Liu, W, Lyu, Q, Zhang, K. | 登録日 | 2020-04-26 | 公開日 | 2021-03-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the substrate-binding cleft of AlyF reveal the first long-chain alginate-binding mode. Acta Crystallogr D Struct Biol, 77, 2021
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7RBY
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![BU of 7rby by Molmil](/molmil-images/mine/7rby) | Crystal structure of Nanobody nb112 and SARS-CoV-2 RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ilama-isolated nanobody NIH-CoV nb-112 specific to SARS-CoV-2 RBD, MAGNESIUM ION, ... | 著者 | Chen, Y, Tolbert, W, Pazgier, M. | 登録日 | 2021-07-06 | 公開日 | 2022-03-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Nebulized delivery of a broadly neutralizing SARS-CoV-2 RBD-specific nanobody prevents clinical, virological, and pathological disease in a Syrian hamster model of COVID-19. Mabs, 14
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7R73
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7RI1
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![BU of 7ri1 by Molmil](/molmil-images/mine/7ri1) | |
7RI2
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![BU of 7ri2 by Molmil](/molmil-images/mine/7ri2) | |
7RFT
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8W4M
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![BU of 8w4m by Molmil](/molmil-images/mine/8w4m) | Crystal structure of open conformation of human immunoglobulin Fc in presence of EndoSz | 分子名称: | Immunoglobulin gamma-1 heavy chain, ZINC ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Guan, H.H, Lin, C.C, Hsieh, Y.C, Chen, C.J. | 登録日 | 2023-08-24 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structure-Based High-Efficiency Homogeneous Antibody Platform by Endoglycosidase Sz Provides Insights into Its Transglycosylation Mechanism. Jacs Au, 4, 2024
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8W4L
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![BU of 8w4l by Molmil](/molmil-images/mine/8w4l) | Crystal structure of closed conformation of human immunoglobulin Fc in presence of EndoSz | 分子名称: | CHLORIDE ION, Immunoglobulin gamma-1 heavy chain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guan, H.H, Lin, C.C, Hsieh, Y.C, Chen, C.J. | 登録日 | 2023-08-24 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure-Based High-Efficiency Homogeneous Antibody Platform by Endoglycosidase Sz Provides Insights into Its Transglycosylation Mechanism. Jacs Au, 4, 2024
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7RC9
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1H49
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![BU of 1h49 by Molmil](/molmil-images/mine/1h49) | CRYSTAL STRUCTURE OF THE INACTIVE DOUBLE MUTANT OF THE MAIZE BETA-GLUCOSIDASE ZMGLU1-E191D-F198V IN COMPLEX WITH DIMBOA-GLUCOSIDE | 分子名称: | 2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE, BETA-GLUCOSIDASE, beta-D-glucopyranose | 著者 | Czjzek, M, Moriniere, J, Verdoucq, L, Bevan, D.R, Henrissat, B, Esen, A. | 登録日 | 2003-02-25 | 公開日 | 2003-03-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mutational and Structural Analysis of Aglycone Specificity in Maize and Sorghum Beta-Glucosidases J.Biol.Chem., 278, 2003
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6YX5
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![BU of 6yx5 by Molmil](/molmil-images/mine/6yx5) | Structure of DrrA from Legionella pneumophilia in complex with human Rab8a | 分子名称: | MAGNESIUM ION, Multifunctional virulence effector protein DrrA, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Schneider, S, Du, J, von Wrisberg, M.K, Lang, K, Itzen, A. | 登録日 | 2020-04-30 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1. Nat Commun, 12, 2021
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8UWA
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7RSY
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![BU of 7rsy by Molmil](/molmil-images/mine/7rsy) | HIV-1 gp120 complex with CJF-III-049-R | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 Clade C1086, N~1~-{(1R,2R,3S)-2-(carbamimidamidomethyl)-3-[(3R)-3,4-dihydroxybutyl]-5-[(methylamino)methyl]-2,3-dihydro-1H-inden-1-yl}-N~2~-(4-chloro-3-fluorophenyl)ethanediamide | 著者 | Liang, S, Hendrickson, W.A. | 登録日 | 2021-08-12 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. Acs Med.Chem.Lett., 12, 2021
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7RSZ
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![BU of 7rsz by Molmil](/molmil-images/mine/7rsz) | HIV-1 gp120 complex with CJF-II-204 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 Clade C1086, N~1~-{(1R,2R,3S)-2-(carbamimidamidomethyl)-3-[(3R)-3,4-dihydroxybutyl]-5-[(methylamino)methyl]-2,3-dihydro-1H-inden-1-yl}-N~2~-(4-chloro-3-fluorophenyl)ethanediamide, ... | 著者 | Liang, S, Hendrickson, W.A. | 登録日 | 2021-08-12 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. Acs Med.Chem.Lett., 12, 2021
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7RSX
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![BU of 7rsx by Molmil](/molmil-images/mine/7rsx) | HIV-1 gp120 complex with CJF-III-049-S | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP120, N~1~-{(1R,2R,3S)-2-(carbamimidamidomethyl)-3-[(3S)-3,4-dihydroxybutyl]-5-[(methylamino)methyl]-2,3-dihydro-1H-inden-1-yl}-N~2~-(4-chloro-3-fluorophenyl)ethanediamide | 著者 | Liang, S, Hendrickson, W.A. | 登録日 | 2021-08-12 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. Acs Med.Chem.Lett., 12, 2021
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7RST
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![BU of 7rst by Molmil](/molmil-images/mine/7rst) | The Crystal Structure of Recombinant Chloroperoxidase Expressed in Aspergillus niger | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chloroperoxidase, ... | 著者 | Tang, X, Venkadesh, S, Zhou, J, Rosen, B, Wang, X. | 登録日 | 2021-08-11 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | The Crystal Structure of Recombinant Chloroperoxidase Expressed in Aspergillus niger To Be Published
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