8BGW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bgw by Molmil](/molmil-images/mine/8bgw) | CryoEM structure of quinol-dependent Nitric Oxide Reductase (qNOR) from Alcaligenes xylosoxidans at 2.2 A resolution | 分子名称: | (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, CALCIUM ION, FE (III) ION, ... | 著者 | Flynn, A, Antonyuk, S.V, Eady, R.R, Muench, S.P, Hasnain, S.S. | 登録日 | 2022-10-28 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | A 2.2 angstrom cryoEM structure of a quinol-dependent NO Reductase shows close similarity to respiratory oxidases. Nat Commun, 14, 2023
|
|
7UUO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uuo by Molmil](/molmil-images/mine/7uuo) | Crystal structure of aminoglycoside resistance enzyme ApmA H135A mutant, complex with tobramycin and coenzyme A | 分子名称: | 1,2-ETHANEDIOL, Aminocyclitol acetyltransferase ApmA, COENZYME A, ... | 著者 | Stogios, P.J, Evdokimova, E, Michalska, K, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-04-28 | 公開日 | 2022-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance. Nat.Chem.Biol., 20, 2024
|
|
3B7E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b7e by Molmil](/molmil-images/mine/3b7e) | Neuraminidase of A/Brevig Mission/1/1918 H1N1 strain in complex with zanamivir | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Xu, X, Zhu, X, Wilson, I.A. | 登録日 | 2007-10-30 | 公開日 | 2008-10-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural characterization of the 1918 influenza virus H1N1 neuraminidase J.Virol., 82, 2008
|
|
3MUP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mup by Molmil](/molmil-images/mine/3mup) | cIAP1-BIR3 domain in complex with the Smac-mimetic compound Smac037 | 分子名称: | (3S,6S,7R,9aS)-6-{[(2S)-2-aminobutanoyl]amino}-7-(2-aminoethyl)-N-(diphenylmethyl)-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide, Baculoviral IAP repeat-containing protein 2, ZINC ION | 著者 | Cossu, F, Malvezzi, F, Canevari, G, Milani, M. | 登録日 | 2010-05-03 | 公開日 | 2010-11-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Recognition of Smac-mimetic compounds by the BIR domain of cIAP1 Protein Sci., 19, 2010
|
|
4JBA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jba by Molmil](/molmil-images/mine/4jba) | |
3BII
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bii by Molmil](/molmil-images/mine/3bii) | Crystal Structure of Activated MPT Synthase | 分子名称: | CHLORIDE ION, Molybdopterin-converting factor subunit 1, Molybdopterin-converting factor subunit 2 | 著者 | Daniels, J.N, Schindelin, H. | 登録日 | 2007-11-30 | 公開日 | 2008-02-19 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency. Biochemistry, 47, 2008
|
|
8P28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p28 by Molmil](/molmil-images/mine/8p28) | Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its tetrameric, dATP-bound state | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-15 | 公開日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site To Be Published
|
|
3N2W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3n2w by Molmil](/molmil-images/mine/3n2w) | Crystal structure of the N-terminal beta-aminopeptidase BapA from Sphingosinicella xenopeptidilytica | 分子名称: | Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION | 著者 | Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G. | 登録日 | 2010-05-19 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family. Structure, 20, 2012
|
|
8P2C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p2c by Molmil](/molmil-images/mine/8p2c) | Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its tetrameric state produced in the presence of dATP and CTP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-15 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site eLife, 2023
|
|
3AT5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3at5 by Molmil](/molmil-images/mine/3at5) | Side-necked turtle (Pleurodira, Chelonia, REPTILIA) hemoglobin: cDNA-derived primary structures and X-ray crystal structures of Hb A | 分子名称: | AlphaA-globin, Beta-globin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hasegawa, T, Shishikura, F, Kuwada, T. | 登録日 | 2010-12-26 | 公開日 | 2011-04-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Side-necked turtle (Pleurodira, Chelonia, reptilia) hemoglobin: cDNA-derived primary structures and X-ray crystal structures of Hb A. Iubmb Life, 63, 2011
|
|
8B63
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b63 by Molmil](/molmil-images/mine/8b63) | Crystal Structure of P. aeruginosa WaaG in complex with UDP-GalNAc | 分子名称: | ACETATE ION, UDP-glucose:(Heptosyl) LPS alpha 1,3-glucosyltransferase WaaG, URIDINE-5'-DIPHOSPHATE, ... | 著者 | Scaletti, E, Gustafsson Westergren, R, Stenmark, P. | 登録日 | 2022-09-25 | 公開日 | 2023-10-04 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional insights into the Pseudomonas aeruginosa glycosyltransferase WaaG and the implications for lipopolysaccharide biosynthesis. J.Biol.Chem., 299, 2023
|
|
3ATW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3atw by Molmil](/molmil-images/mine/3atw) | Structure-Based Design, Synthesis, Evaluation of Peptide-mimetic SARS 3CL Protease Inhibitors | 分子名称: | 3C-Like Proteinase, peptide ACE-THR-VAL-ALC-HIS-H | 著者 | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | 登録日 | 2011-01-20 | 公開日 | 2011-12-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
|
|
3AT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3at6 by Molmil](/molmil-images/mine/3at6) | Side-necked turtle (Pleurodira, Chelonia, REPTILIA) hemoglobin: cDNA-derived primary structures and X-ray crystal structures of Hb A | 分子名称: | AlphaA-globin, Beta-globin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hasegawa, T, Shishikura, F, Kuwada, T. | 登録日 | 2010-12-26 | 公開日 | 2011-04-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Side-necked turtle (Pleurodira, Chelonia, reptilia) hemoglobin: cDNA-derived primary structures and X-ray crystal structures of Hb A. Iubmb Life, 63, 2011
|
|
4MPV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mpv by Molmil](/molmil-images/mine/4mpv) | Human beta-tryptase co-crystal structure with (2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamide | 分子名称: | (2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | White, A, Stein, A.J, Suto, R. | 登録日 | 2013-09-13 | 公開日 | 2015-03-18 | 最終更新日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (2.305 Å) | 主引用文献 | Target-Directed Self-Assembly of Homodimeric Drugs Against beta-Tryptase. Acs Med.Chem.Lett., 9, 2018
|
|
4I4I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i4i by Molmil](/molmil-images/mine/4i4i) | Crystal Structure of Bacillus stearothermophilus Phosphofructokinase mutant T156A bound to PEP | 分子名称: | 6-phosphofructokinase, PHOSPHOENOLPYRUVATE | 著者 | Mosser, R, Reddy, M, Bruning, J.B, Sacchettini, J.C, Reinhart, G.D. | 登録日 | 2012-11-27 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4948 Å) | 主引用文献 | Redefining the Role of the Quaternary Shift in Bacillus stearothermophilus Phosphofructokinase. Biochemistry, 52, 2013
|
|
3ODM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3odm by Molmil](/molmil-images/mine/3odm) | Archaeal-type phosphoenolpyruvate carboxylase | 分子名称: | GOLD (I) CYANIDE ION, MALONATE ION, Phosphoenolpyruvate carboxylase | 著者 | Dunten, P.W. | 登録日 | 2010-08-11 | 公開日 | 2011-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure of an archaeal-type phosphoenolpyruvate carboxylase sensitive to inhibition by aspartate. Proteins, 79, 2011
|
|
3C25
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c25 by Molmil](/molmil-images/mine/3c25) | Crystal Structure of NotI Restriction Endonuclease Bound to Cognate DNA | 分子名称: | CALCIUM ION, DNA (5'-D(*DCP*DGP*DGP*DAP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DGP*DCP*DCP*DG)-3'), DNA (5'-D(*DCP*DGP*DGP*DCP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DTP*DCP*DCP*DG)-3'), ... | 著者 | Lambert, A.R, Sussman, D, Shen, B, Stoddard, B.L. | 登録日 | 2008-01-24 | 公開日 | 2008-02-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding. Structure, 16, 2008
|
|
4I5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i5g by Molmil](/molmil-images/mine/4i5g) | Crystal structure of Ralstonia sp. alcohol dehydrogenase mutant N15G, G37D, R38V, R39S, A86N, S88A | 分子名称: | Alclohol dehydrogenase/short-chain dehydrogenase | 著者 | Jarasch, A, Lerchner, A, Meining, W, Schiefner, A, Skerra, A. | 登録日 | 2012-11-28 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol.Bioeng., 110, 2013
|
|
4JTK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jtk by Molmil](/molmil-images/mine/4jtk) | Crystal structure of R117Q mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION | 著者 | Allison, T.M, Cochrane, F.C, Jameson, G.B, Parker, E.J. | 登録日 | 2013-03-23 | 公開日 | 2013-06-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase. Biochemistry, 52, 2013
|
|
3PW1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pw1 by Molmil](/molmil-images/mine/3pw1) | |
8EQM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eqm by Molmil](/molmil-images/mine/8eqm) | Structure of a dimeric photosystem II complex acclimated to far-red light | 分子名称: | (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | 著者 | Gisriel, C.J, Shen, G, Flesher, D.A, Kurashov, V, Golbeck, J.H, Brudvig, G.W, Amin, M, Bryant, D.A. | 登録日 | 2022-10-08 | 公開日 | 2022-12-28 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structure of a dimeric photosystem II complex from a cyanobacterium acclimated to far-red light. J.Biol.Chem., 299, 2022
|
|
3BPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bpz by Molmil](/molmil-images/mine/3bpz) | |
1UP7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1up7 by Molmil](/molmil-images/mine/1up7) | Structure of the 6-phospho-beta glucosidase from Thermotoga maritima at 2.4 Angstrom resolution in the tetragonal form with NAD and glucose-6-phosphate | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, 6-PHOSPHO-BETA-GLUCOSIDASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Varrot, A, Yip, V.L, Withers, S.G, Davies, G.J. | 登録日 | 2003-09-29 | 公開日 | 2004-11-18 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Nad+ and Metal-Ion Dependent Hydrolysis by Family 4 Glycosidases: Structural Insight Into Specificity for Phospho-Beta-D-Glucosides J.Mol.Biol., 346, 2005
|
|
4OE2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oe2 by Molmil](/molmil-images/mine/4oe2) | 2.00 Angstroms X-ray crystal structure of E268A 2-aminomuconate 6-semialdehyde dehydrogenase from Pseudomonas fluorescens | 分子名称: | 2-aminomuconate 6-semialdehyde dehydrogenase, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Huo, L, Davis, I, Liu, F, Esaki, S, Iwaki, H, Hasegawa, Y, Liu, A. | 登録日 | 2014-01-11 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallographic and spectroscopic snapshots reveal a dehydrogenase in action. Nat Commun, 6, 2015
|
|
2YJN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yjn by Molmil](/molmil-images/mine/2yjn) | Structure of the glycosyltransferase EryCIII from the erythromycin biosynthetic pathway, in complex with its activating partner, EryCII | 分子名称: | DTDP-4-KETO-6-DEOXY-HEXOSE 3,4-ISOMERASE, GLYCOSYLTRANSFERASE | 著者 | Moncrieffe, M.C, Fernandez, M.J, Spiteller, D, Matsumura, H, Gay, N.J, Luisi, B.F, Leadlay, P.F. | 登録日 | 2011-05-20 | 公開日 | 2011-11-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.091 Å) | 主引用文献 | Structure of the Glycosyltransferase Eryciii in Complex with its Activating P450 Homologue Erycii. J.Mol.Biol., 415, 2012
|
|