5XDJ
 
 | | Esculentin-1a(1-21)NH2 | | 分子名称: | Esculentin-1A | | 著者 | Ghosh, A, Bhunia, A. | | 登録日 | 2017-03-28 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Membrane perturbing activities and structural properties of the frog-skin derived peptide Esculentin-1a(1-21)NH2 and its Diastereomer Esc(1-21)-1c: Correlation with their antipseudomonal and cytotoxic activity
Biochim. Biophys. Acta, 1859, 2017
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6I6F
 | | SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 1 | | 分子名称: | 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Sepiapterin reductase, ... | | 著者 | Alen, J, Schade, M, Wagener, M, Blaesse, M. | | 登録日 | 2018-11-15 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors.
J.Med.Chem., 62, 2019
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6I6V
 | | SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 6 | | 分子名称: | 1,2-ETHANEDIOL, 2-[[(3~{R})-oxan-3-yl]methylsulfonyl]-2-azaspiro[4.5]decane, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Alen, J, Schade, M, Wagener, M, Blaesse, M. | | 登録日 | 2018-11-15 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors.
J.Med.Chem., 62, 2019
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6I42
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6AEZ
 | | Crystal structure of human CCL5 trimer | | 分子名称: | C-C motif chemokine 5, SULFATE ION | | 著者 | Chen, Y.C, Li, K.M, Chen, P.J, Zarivach, R, Sun, Y.J, Sue, S.C. | | 登録日 | 2018-08-07 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5.
J.Mol.Biol., 432, 2020
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6AC7
 | | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter | | 分子名称: | 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*GP*AP*GP*GP*CP*GP*GP*GP*GP*CP*TP*TP*GP*GP*G)-3' | | 著者 | Sengar, A, Vandana, J.J, Chambers, V.S, Di Antonio, M, Winnerdy, F.R, Balasubramanian, S, Phan, A.T. | | 登録日 | 2018-07-25 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter.
Nucleic Acids Res., 47, 2019
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1UOW
 | | Calcium binding domain C2B | | 分子名称: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Cheng, Y, Sequeira, S.M, Sollner, T.H, Patel, D.J. | | 登録日 | 2003-09-24 | | 公開日 | 2004-09-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
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6IZP
 | | Solution structure of the complex of naphthyridine carbamate dimer and an RNA with UGGAA-UGGAA pentad | | 分子名称: | 3-[3-[(7-methyl-1,8-naphthyridin-2-yl)carbamoyloxy]propylamino]propyl ~{N}-(7-methyl-1,8-naphthyridin-2-yl)carbamate, RNA (29-MER) | | 著者 | Nagano, K, Shibata, T, Nakatani, K, Kawai, G. | | 登録日 | 2018-12-20 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model
Nat Commun, 12, 2021
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6J13
 | | Redox protein from Chlamydomonas reinhardtii | | 分子名称: | 2-cys peroxiredoxin | | 著者 | Charoenwattansatien, R, Zinzius, K, Tanaka, H, Hippler, M, Kurisu, G. | | 登録日 | 2018-12-27 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Calcium sensing via EF-hand 4 enables thioredoxin activity in the sensor-responder protein calredoxin in the green algaChlamydomonas reinhardtii.
J.Biol.Chem., 295, 2020
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6AAU
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6JIE
 | | YaeO bound to Magnesium from Vibrio cholerae O395 | | 分子名称: | MAGNESIUM ION, YaeO | | 著者 | Pal, K, Yadav, M, Sen, U. | | 登録日 | 2019-02-20 | | 公開日 | 2019-12-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Vibrio cholerae YaeO is a Structural Homologue of RNA Chaperone Hfq that Inhibits Rho-dependent Transcription Termination by Dissociating its Hexameric State.
J.Mol.Biol., 431, 2019
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1HKN
 | | A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate | | 分子名称: | 5-AMINO-NAPHTALENE-2-MONOSULFONATE, HEPARIN-BINDING GROWTH FACTOR 1 | | 著者 | Fernandez-Tornero, C, Lozano, R.M, Gimenez-Gallego, G, Romero, A. | | 登録日 | 2003-03-10 | | 公開日 | 2004-03-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
J.Biol.Chem., 278, 2003
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6L4Z
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6LE1
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5ZSY
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6AC9
 | | Crystal structure of human Vaccinia-related kinase 1 (VRK1) in complex with AMP-PNP | | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Ngow, Y.S, Sreekanth, R, Yoon, H.S. | | 登録日 | 2018-07-25 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Crystal structure of human vaccinia-related kinase 1 in complex with AMP-PNP, a non-hydrolyzable ATP analog.
Protein Sci., 28, 2019
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1UOV
 | | Calcium binding domain C2B | | 分子名称: | CALCIUM ION, GLYCEROL, SYNAPTOTAGMIN I | | 著者 | Cheng, Y, Sequeira, S.M, Sollner, T.H, Patel, D.J. | | 登録日 | 2003-09-24 | | 公開日 | 2004-09-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
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6L6O
 | | Crystal structure of stabilized Rab5a GTPase domain from Leishmania donovani | | 分子名称: | ACETATE ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Arora, A, Zohib, M, Biswal, B.K, Maheshwari, D, Pal, R.K. | | 登録日 | 2019-10-29 | | 公開日 | 2020-11-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the GDP-bound GTPase domain of Rab5a from Leishmania donovani.
Acta Crystallogr.,Sect.F, 76, 2020
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6KXB
 | | Galectin-3 CRD binds to GalA trimer | | 分子名称: | Galectin-3, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-beta-D-galactopyranuronic acid | | 著者 | Su, J. | | 登録日 | 2019-09-10 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Topsy-turvy binding of negatively charged homogalacturonan oligosaccharides to galectin-3.
Glycobiology, 31, 2021
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6L1S
 | | Crystal structure of DUSP22 mutant_C88S | | 分子名称: | Dual specificity protein phosphatase 22, PHOSPHATE ION | | 著者 | Lai, C.H, Chang, C.C, Lyu, P.C. | | 登録日 | 2019-09-30 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.3611 Å) | | 主引用文献 | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020
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1TJM
 | | Crystallographic Identification of Sr2+ Coordination Site in Synaptotagmin I C2B Domain | | 分子名称: | GLYCEROL, STRONTIUM ION, Synaptotagmin I | | 著者 | Cheng, Y, Sequeira, S.M, Malinina, L, Tereshko, V, Sollner, T.H, Patel, D.J. | | 登録日 | 2004-06-06 | | 公開日 | 2004-09-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain
Protein Sci., 13, 2004
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1MID
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2YCZ
 | | TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST IODOCYANOPINDOLOL | | 分子名称: | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3-iodo-1H-indole-2-carbonitrile, BETA-1 ADRENERGIC RECEPTOR, octyl 1-thio-beta-D-glucopyranoside | | 著者 | Moukhametzianov, R, Warne, T, Edwards, P.C, Serrano-Vega, M.J, Leslie, A.G.W, Tate, C.G, Schertler, G.F.X. | | 登録日 | 2011-03-17 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a {Beta}1- Adrenergic Receptor.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y7X
 | | The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs | | 分子名称: | 6-CHLORO-N-[(3S)-1-(5-FLUORO-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL)-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | | 著者 | Watson, N.S, Adams, C, Belton, D, Brown, D, Burns-Kurtis, C.L, Chaudry, L, Chan, C, Convery, M.A, Davies, D.E, Exall, A.M, Harling, J.D, Irving, W.R, Irvine, S, Kleanthous, S, McLay, I.M, Pateman, A.J, Patikis, A.N, Roethka, T.J, Senger, S, Stelman, G.J, Toomey, J.R, West, R.I, Whittaker, C, Zhou, P, Young, R.J. | | 登録日 | 2011-02-02 | | 公開日 | 2011-03-16 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Discovery of Potent and Long-Acting Oral Factor Xa Inhibitors with Tetrahydroisoquinoline and Benzazepine P4 Motifs.
Bioorg.Med.Chem.Lett., 21, 2011
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2YB6
 | | Native human Rad6 | | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, UBIQUITIN-CONJUGATING ENZYME E2 B | | 著者 | Hibbert, R.G, Sixma, T.K. | | 登録日 | 2011-03-02 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6.
Proc.Natl.Acad.Sci.USA, 108, 2011
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