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1PO5
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Structure of mammalian cytochrome P450 2B4
分子名称: Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
著者Scott, E.E, He, Y.A, Wester, M.R, White, M.A, Chin, C.C, Halpert, J.R, Johnson, E.F, Stout, C.D.
登録日2003-06-13
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献An open conformation of mammalian cytochrome P450 2B4 at 1.6 A resolution
Proc.Natl.Acad.Sci.USA, 100, 2003
3SA9
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BU of 3sa9 by Molmil
Crystal structure of Wild-type HIV-1 protease in complex With AF68
分子名称: ACETATE ION, N~2~-acetyl-N-[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]-L-isoleucinamide, PHOSPHATE ION, ...
著者Schiffer, C.A, Nalam, M.N.L.
登録日2011-06-02
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance
To be Published
6EIY
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Crystal structure of KDM5B in complex with KDOPZ000034a.
分子名称: 1,2-ETHANEDIOL, 2-chloranyl-~{N}-[2-[4-(3-cyano-7-oxidanylidene-6-propan-2-yl-4~{H}-pyrazolo[1,5-a]pyrimidin-5-yl)pyrazol-1-yl]ethyl]ethanamide, DIMETHYL SULFOXIDE, ...
著者Srikannathasan, V, Newman, J.A, Szykowska, A, Wright, M, Ruda, G.F, Vazquez-Rodriguez, S.A, Kupinska, K, Strain-Damerell, C, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Huber, K, von Delft, F.
登録日2017-09-19
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of KDM5B in complex with KDOPZ000034a.
to be published
1PQ2
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Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
分子名称: Cytochrome P450 2C8, PALMITIC ACID, PHOSPHATE ION, ...
著者Schoch, G.A, Yano, J.K, Wester, M.R, Griffin, K.J, Stout, C.D, Johnson, E.F.
登録日2003-06-17
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site
J.Biol.Chem., 279, 2004
3SEC
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Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate
分子名称: (1S)-1,4-anhydro-1-(5-carbamoyl-4-hydroxy-1H-pyrazol-3-yl)-5-O-phosphono-D-ribitol, GLYCEROL, Orotidine 5'-phosphate decarboxylase
著者Liu, Y, Kotra, L.P, Pai, E.F.
登録日2011-06-10
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of methanococcus thermolithotrophicus orotidine 5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate
To be Published
3SHF
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BU of 3shf by Molmil
Crystal structure of the R265S mutant of full-length murine Apaf-1
分子名称: ADENOSINE-5'-DIPHOSPHATE, Apoptotic peptidase activating factor 1, GAMMA-BUTYROLACTONE
著者Eschenburg, S, Reubold, T.F.
登録日2011-06-16
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Crystal structure of full-length Apaf-1: how the death signal is relayed in the mitochondrial pathway of apoptosis.
Structure, 19, 2011
3SI0
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BU of 3si0 by Molmil
Structure of glycosylated human glutaminyl cyclase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutaminyl-peptide cyclotransferase, ...
著者Parthier, C, Carrillo, D, Stubbs, M.T.
登録日2011-06-17
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of Glycosylated Mammalian Glutaminyl Cyclases Reveal Conformational Variability near the Active Center.
Biochemistry, 50, 2011
2G33
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Human Hepatitis B Virus T=4 capsid, strain adyw
分子名称: Core antigen
著者Bourne, C.R, Zlotnick, A.
登録日2006-02-17
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.96 Å)
主引用文献Global Structural Changes in Hepatitis B Virus Capsids Induced by the Assembly Effector HAP1.
J.Virol., 80, 2006
1PVN
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BU of 1pvn by Molmil
The crystal structure of the complex between IMP dehydrogenase catalytic domain and a transition state analogue MZP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-CARBAMOYL-1-BETA-D-RIBOFURANOSYL-IMIDAZOLIUM-5-OLATE-5'-PHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ...
著者Gan, L, Seyedsayamdost, M, Shuto, S, Matsuda, A, Petsko, G.A, Hedstrom, L.
登録日2003-06-27
公開日2003-07-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Immunosuppressive Agent Mizoribine Monophosphate Forms a Transition State Analogue Complex with Inosine Monophosphate Dehydrogenase
Biochemistry, 42, 2003
3HKJ
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Crystal structure of human thrombin mutant W215A/E217A in complex with the extracellular fragment of human PAR1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Proteinase-activated receptor 1, Thrombin heavy chain, ...
著者Gandhi, P.S, Page, M.J, Chen, Z, Bush-Pelc, L, Di Cera, E.
登録日2009-05-23
公開日2009-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A.
J.Biol.Chem., 284, 2009
2FS6
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BU of 2fs6 by Molmil
Crystal Structure of Apo-Cellular Retinoic Acid Binding Protein Type II At 1.35 Angstroms Resolution
分子名称: ACETATE ION, CHLORIDE ION, Cellular retinoic acid-binding protein 2, ...
著者Vaezeslami, S, Geiger, J.H.
登録日2006-01-21
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The structure of Apo-wild-type cellular retinoic acid binding protein II at 1.4 A and its relationship to ligand binding and nuclear translocation.
J.Mol.Biol., 363, 2006
3HE7
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BU of 3he7 by Molmil
Crystal structure of mouse CD1d-alpha-galactosylceramide with mouse Valpha14-Vbeta7 NKT TCR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Patel, O, Rossjohn, J.
登録日2009-05-08
公開日2009-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors
Immunity, 31, 2009
2G54
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BU of 2g54 by Molmil
Crystal structure of Zn-bound human insulin-degrading enzyme in complex with insulin B chain
分子名称: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, ZINC ION, ...
著者Shen, Y, Tang, W.-J.
登録日2006-02-22
公開日2006-10-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
3S6P
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BU of 3s6p by Molmil
Crystal Structure of Helicoverpa Armigera Stunt Virus
分子名称: CALCIUM ION, CHLORIDE ION, Capsid protein
著者Speir, J.A, Chen, Z, Taylor, D.J, Johnson, J.E.
登録日2011-05-25
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Helicoverpa armigera stunt virus
To be Published
6E8G
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BU of 6e8g by Molmil
CryoEM reconstruction of IST1-CHMP1B copolymer filament bound to ssDNA at 2.9 Angstrom resolution
分子名称: Charged multivesicular body protein 1b, IST1 homolog
著者Talledge, N, Frost, A, McCullough, J.
登録日2018-07-29
公開日2018-08-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The ESCRT-III proteins IST1 and CHMP1B assemble around nucleic acids
Biorxiv, 2018
3HDH
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BU of 3hdh by Molmil
PIG HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE REVISITED: SEQUENCE ANALYSIS AND CRYSTAL STRUCTURE DETERMINATION
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (L-3-HYDROXYACYL COA DEHYDROGENASE)
著者Barycki, J.J, O'Brien, L.K, Birktoft, J.J, Strauss, A.W, Banaszak, L.J.
登録日1999-04-13
公開日1999-10-08
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Pig heart short chain L-3-hydroxyacyl-CoA dehydrogenase revisited: sequence analysis and crystal structure determination.
Protein Sci., 8, 1999
1Q0X
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BU of 1q0x by Molmil
Anti-morphine Antibody 9B1 Unliganded Form
分子名称: Fab 9B1, heavy chain, light chain, ...
著者Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D.
登録日2003-07-17
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine
J.Mol.Biol., 337, 2004
6EMW
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BU of 6emw by Molmil
Structure of S.aureus ClpC in complex with MecA
分子名称: ATP-dependent Clp protease ATP-binding subunit, ATP-dependent Clp protease ATP-binding subunit ClpC, Adapter protein MecA, ...
著者Carroni, M, Mogk, A, Bukau, B, Franke, K.
登録日2017-10-03
公開日2017-12-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
3JBP
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BU of 3jbp by Molmil
Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to E-tRNA
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ...
著者Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J.
登録日2015-09-16
公開日2015-10-14
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
3W07
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Atomic resolution structure of orotidine 5'-monophosphate decarboxylase from Methanothermobacter thermoautotrophicus bound with UMP.
分子名称: GLYCEROL, Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE
著者Fujihashi, M, Pai, E.F, Miki, K.
登録日2012-10-22
公開日2013-02-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Atomic resolution structure of the orotidine 5'-monophosphate decarboxylase product complex combined with surface plasmon resonance analysis: implications for the catalytic mechanism.
J.Biol.Chem., 288, 2013
1M93
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1.65 A Structure of Cleaved Viral Serpin CRMA
分子名称: PHOSPHATE ION, Serine proteinase inhibitor 2
著者Simonovic, M, Gettins, P.G.W, Volz, K.
登録日2002-07-26
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition
Protein Sci., 9, 2000
3J5L
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Structure of the E. coli 50S subunit with ErmBL nascent chain
分子名称: 23S ribsomal RNA, 5'-R(*CP*(MA6))-3', 5'-R(*CP*CP*A)-3', ...
著者Arenz, S, Ramu, H, Gupta, P, Berninghausen, O, Beckmann, R, Vazquez-Laslop, N, Mankin, A.S, Wilson, D.N.
登録日2013-10-23
公開日2014-03-26
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide.
Nat Commun, 5, 2014
1MDY
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CRYSTAL STRUCTURE OF MYOD BHLH DOMAIN BOUND TO DNA: PERSPECTIVES ON DNA RECOGNITION AND IMPLICATIONS FOR TRANSCRIPTIONAL ACTIVATION
分子名称: DNA (5'-D(*TP*CP*AP*AP*CP*AP*GP*CP*TP*GP*TP*TP*GP*A)-3'), PROTEIN (MYOD BHLH DOMAIN)
著者Ma, P.C.M, Rould, M.A, Weintraub, H, Pabo, C.O.
登録日1994-06-09
公開日1994-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activation.
Cell(Cambridge,Mass.), 77, 1994
3JA8
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Cryo-EM structure of the MCM2-7 double hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ...
著者Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N.
登録日2015-05-09
公開日2015-08-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
1MJ5
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LINB (haloalkane dehalogenase) from sphingomonas paucimobilis UT26 at atomic resolution
分子名称: 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase, CHLORIDE ION, MAGNESIUM ION
著者Oakley, A.J, Damborsky, J, Wilce, M.C.
登録日2002-08-27
公開日2003-08-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Crystal structure of haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26 at 0.95 A resolution: dynamics of catalytic residues.
Biochemistry, 43, 2004

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