PDB: 274 件ウェブページステータス検索Chemie searchBIRD

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8P1P	USP28 in complex with AZ1 分子名称: 2-[[5-bromanyl-2-[[4-fluoranyl-3-(trifluoromethyl)phenyl]methoxy]phenyl]methylamino]ethanol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Sauer, F, Karal-Nair, R, Kisker, C. 登録日 2023-05-12 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 USP28 in complex with AZ1 To Be Published
8P1Q	USP28 in complex with FT206 分子名称: 3-azanyl-N-[(2S)-6-[(1S,5R)-3,8-diazabicyclo[3.2.1]octan-3-yl]-1,2,3,4-tetrahydronaphthalen-2-yl]-6-methyl-thieno[2,3-b]pyridine-2-carboxamide, DIMETHYL SULFOXIDE, Ubiquitin carboxyl-terminal hydrolase 28 著者 Sauer, F, Karal Nair, R, Kisker, C. 登録日 2023-05-12 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 USP28 in complex with FT206 To Be Published
3MHH	Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module 分子名称: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ... 著者 Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. 登録日 2010-04-08 公開日 2010-04-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural insights into the assembly and function of the SAGA deubiquitinating module. Science, 328, 2010
3MHS	Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ... 著者 Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. 登録日 2010-04-08 公開日 2010-04-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural insights into the assembly and function of the SAGA deubiquitinating module. Science, 328, 2010
3NHE	High Resolution Structure (1.26A) of USP2a in Complex with Ubiquitin 分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ZINC ION 著者 Schormann, N, DeLucas, L.J, Powell McCombs, D. 登録日 2010-06-14 公開日 2010-06-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 High resolution structure of USP2a in complex with ubiquitin To be Published
3MTN	Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor 分子名称: CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ... 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2010-04-30 公開日 2010-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
3N3K	The catalytic domain of USP8 in complex with a USP8 specific inhibitor 分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Allali-Hassani, A, Lam, R, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium, Structural Genomics Consortium (SGC) 登録日 2010-05-20 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
2J7Q	Crystal structure of the ubiquitin-specific protease encoded by murine cytomegalovirus tegument protein M48 in complex with a ubquitin-based suicide substrate 分子名称: GLYCEROL, MAGNESIUM ION, MCMV TEGUMENT PROTEIN M48 ENCODED UBIQUITIN- SPECIFIC PROTEASE, ... 著者 Schlieker, C, Weihofen, W.A, Frijns, E, Kattenhorn, L.M, Gaudet, R, Ploegh, H.L. 登録日 2006-10-16 公開日 2007-03-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of Deubiquitinating Enzymes Mol.Cell, 25, 2007
5JTJ	USP7CD-CTP in complex with Ubiquitin 分子名称: CALCIUM ION, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin carboxyl-terminal hydrolase 7 著者 Murray, J.M, Rouge, L. 登録日 2016-05-09 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.321 Å) 主引用文献 Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation. Structure, 24, 2016
5JTV	USP7CD-UBL45 in complex with Ubiquitin 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7 著者 Murray, J.M, Rouge, L. 登録日 2016-05-09 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.312 Å) 主引用文献 Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation. Structure, 24, 2016
5L8W	Structure of USP12-UB-PRG/UAF1 分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 12, ... 著者 Dharadhar, S, Sixma, T. 登録日 2016-06-08 公開日 2016-09-28 最終更新日 2016-11-30 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme. J.Struct.Biol., 196, 2016
5KYC	Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin (malonate bound) 分子名称: GLYCEROL, MALONIC ACID, Polyubiquitin-B, ... 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.426 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
5KYF	Crystal structure of USP7 catalytic domain [L299A] mutant in complex with ubiquitin 分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
5KYB	Crystal structure of the apo-form of USP7 catalytic domain [V302K] mutant 分子名称: GLYCEROL, Ubiquitin carboxyl-terminal hydrolase 7 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
5KYE	Crystal structure of USP7 catalytic domain [H294E] mutant in complex with ubiquitin 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
5L8H	Structure of USP46-UbVME 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION 著者 Clerici, M, Sixma, T, Dharadhar, S. 登録日 2016-06-07 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme. J.Struct.Biol., 196, 2016
5KYD	Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
7W3F	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3B	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W37	Structure of USP14-bound human 26S proteasome in state EA1_UBL 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3H	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3G	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W39	Structure of USP14-bound human 26S proteasome in state EA2.1_UBL 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3C	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W38	Structure of USP14-bound human 26S proteasome in state EA2.0_UBL 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022

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