6QU1
 
 | | Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain at 3.7 angstrom resolution. | | 分子名称: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta,Transcription intermediary factor 1-beta, ZINC ION | | 著者 | Newman, J.A, Aitkenhead, H, Gavard, A, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2019-02-26 | | 公開日 | 2019-07-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.
Structure, 2019
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1A3S
 | | HUMAN UBC9 | | 分子名称: | UBC9 | | 著者 | Naismith, J.H, Giraud, M. | | 登録日 | 1998-01-23 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin.
Acta Crystallogr.,Sect.D, 54, 1998
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8OX0
 | | Structure of apo telomeric nucleosome | | 分子名称: | Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ... | | 著者 | Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D. | | 登録日 | 2023-04-28 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
Sci Adv, 9, 2023
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8P4C
 | | Structural insights into human co-transcriptional capping - structure 3 | | 分子名称: | DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... | | 著者 | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | | 登録日 | 2023-05-20 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
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8P4D
 | | Structural insights into human co-transcriptional capping - structure 4 | | 分子名称: | DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... | | 著者 | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | | 登録日 | 2023-05-20 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
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8ONS
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8OUE
 | | The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in a semi-closed conformation | | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | | 著者 | Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. | | 登録日 | 2023-04-22 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein.
Nat Commun, 15, 2024
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8OUF
 | | The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in an open conformation | | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | | 著者 | Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. | | 登録日 | 2023-04-22 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein.
Nat Commun, 15, 2024
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8P09
 | | 48S late-stage initiation complex with non methylated mRNA | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | | 著者 | Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. | | 登録日 | 2023-05-09 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | N 6 -methyladenosine in 5' UTR does not promote translation initiation.
Mol.Cell, 84, 2024
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8P03
 | | 48S late-stage initiation complex with m6A mRNA | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | | 著者 | Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. | | 登録日 | 2023-05-09 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | N 6 -methyladenosine in 5' UTR does not promote translation initiation.
Mol.Cell, 84, 2024
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1L3K
 | | UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 | | 分子名称: | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 | | 著者 | Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M. | | 登録日 | 2002-02-27 | | 公開日 | 2002-04-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.
Nucleic Acids Res., 30, 2002
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6H3A
 | | Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain. | | 分子名称: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta, ZINC ION | | 著者 | Newman, J.A, Aitkenhead, H, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2018-07-17 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (5.505 Å) | | 主引用文献 | A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.
Structure, 27, 2019
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7Q3L
 | | Human 17S U2 snRNP 5' domain | | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | | 著者 | Tholen, J, Galej, W.P. | | 登録日 | 2021-10-28 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.21 Å) | | 主引用文献 | Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
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7R5K
 | | Human nuclear pore complex (constricted) | | 分子名称: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | | 著者 | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | | 登録日 | 2022-02-10 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | AI-based structure prediction empowers integrative structural analysis of human nuclear pores.
Science, 376, 2022
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7R5J
 | | Human nuclear pore complex (dilated) | | 分子名称: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | | 著者 | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | | 登録日 | 2022-02-10 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (50 Å) | | 主引用文献 | AI-based structure prediction empowers integrative structural analysis of human nuclear pores
Science, 376, 2022
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6JLB
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1PGZ
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4M38
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2KRR
 | | Solution structure of the RBD1,2 domains from human nucleolin | | 分子名称: | Nucleolin | | 著者 | Arumugam, N, Miller, C, Maliekal, J, Bates, P.J, Trent, J.O, Lane, A.N. | | 登録日 | 2009-12-22 | | 公開日 | 2010-05-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the RBD1,2 domains from human nucleolin.
J.Biomol.Nmr, 47, 2010
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2N1V
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7SYN
 | | Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII) | | 分子名称: | 18S rRNA, 40S ribosomal protein S2, HCV IRES, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
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7SYG
 | | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII) | | 分子名称: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
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7SYM
 | | Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII) | | 分子名称: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway
To Be Published
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7SYU
 | | Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII) | | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
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7SYT
 | | Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt) | | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
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