PDB: 5373 件ウェブページステータス検索Chemie searchBIRD

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7SYT	Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt) 分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... 著者 Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. 登録日 2021-11-25 公開日 2022-07-13 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYG	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII) 分子名称: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ... 著者 Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. 登録日 2021-11-25 公開日 2022-07-13 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
7SU3	CryoEM structure of DNA-PK complex VII 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), ... 著者 Chen, X, Liu, L, Gellert, M, Yang, W. 登録日 2021-11-16 公開日 2022-01-12 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Autophosphorylation transforms DNA-PK from protecting to processing DNA ends. Mol.Cell, 82, 2022
4F6N	Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA 分子名称: DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ... 著者 Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. 登録日 2012-05-15 公開日 2012-09-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proc.Natl.Acad.Sci.USA, 109, 2012
4F6M	Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA 分子名称: DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ... 著者 Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. 登録日 2012-05-15 公開日 2012-09-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proc.Natl.Acad.Sci.USA, 109, 2012
4F3L	Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex 分子名称: BMAL1b, Circadian locomoter output cycles protein kaput 著者 Huang, N, Chelliah, Y, Shan, Y, Taylor, C, Yoo, S, Partch, C, Green, C.B, Zhang, H, Takahashi, J. 登録日 2012-05-09 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.268 Å) 主引用文献 Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex. Science, 337, 2012
7D58	cryo-EM structure of human RNA polymerase III in elongating state 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. 登録日 2020-09-25 公開日 2021-02-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
7D59	cryo-EM structure of human RNA polymerase III in apo state 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. 登録日 2020-09-25 公開日 2021-02-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
8Y6O	Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. 登録日 2024-02-02 公開日 2024-03-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome. Science, 383, 2024
6SWA	Mus musculus brain neocortex ribosome 60S bound to Ebp1 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Kraushar, M.L, Sprink, T. 登録日 2019-09-20 公開日 2020-09-30 最終更新日 2021-02-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit. Mol.Cell, 81, 2021
1PGZ	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI) 分子名称: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*GP*(6MI)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1 著者 Myers, J.C, Moore, S.A, Shamoo, Y. 登録日 2003-05-28 公開日 2003-11-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures J.Biol.Chem., 278, 2003
6FF4	human Bact spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. 登録日 2018-01-03 公開日 2018-08-29 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
6H3A	Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain. 分子名称: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta, ZINC ION 著者 Newman, J.A, Aitkenhead, H, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2018-07-17 公開日 2019-06-26 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (5.505 Å) 主引用文献 A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin. Structure, 27, 2019
2VRR	Structure of SUMO modified Ubc9 分子名称: FORMIC ACID, SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, ... 著者 Knipscheer, P, Flotho, A, Klug, H, Olsen, J.V, van Dijk, W.J, Fish, A, Johnson, E.S, Mann, M, Sixma, T.K, Pichler, A. 登録日 2008-04-13 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Ubc9 sumoylation regulates SUMO target discrimination. Mol. Cell, 31, 2008
7OBB	Cryo-EM structure of human RNA Polymerase I Open Complex 分子名称: DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ... 著者 Misiaszek, A.D, Girbig, M, Mueller, C.W. 登録日 2021-04-21 公開日 2021-12-08 最終更新日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
7OB9	Cryo-EM structure of human RNA Polymerase I in elongation state 分子名称: DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ... 著者 Misiaszek, A.D, Girbig, M, Mueller, C.W. 登録日 2021-04-21 公開日 2021-12-08 最終更新日 2021-12-22 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
7OBA	Cryo-EM structure of human RNA Polymerase I in complex with RRN3 分子名称: DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... 著者 Misiaszek, A.D, Girbig, M, Mueller, C.W. 登録日 2021-04-21 公開日 2021-12-08 最終更新日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
5XF3	Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration) 分子名称: (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... 著者 Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. 登録日 2017-04-07 公開日 2017-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation Nat Commun, 8, 2017
7NVM	Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Actin, ... 著者 Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W, Structural Genomics Consortium (SGC) 登録日 2021-03-15 公開日 2022-03-02 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Snapshots of actin and tubulin folding inside the TRiC chaperonin. Nat.Struct.Mol.Biol., 29, 2022
3KLT	Crystal structure of a vimentin fragment 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CALCIUM ION, HEXAETHYLENE GLYCOL, ... 著者 Nicolet, S, Strelkov, S.V. 登録日 2009-11-09 公開日 2010-05-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Atomic structure of vimentin coil 2. J.Struct.Biol., 170, 2010
7NVO	Human TRiC complex in open state with nanobody bound 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... 著者 Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W. 登録日 2021-03-15 公開日 2022-03-02 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Snapshots of actin and tubulin folding inside the TRiC chaperonin. Nat.Struct.Mol.Biol., 29, 2022
5XF5	Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,S-configuration) 分子名称: (1S,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... 著者 Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. 登録日 2017-04-07 公開日 2017-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation Nat Commun, 8, 2017
2ASQ	Solution Structure of SUMO-1 in Complex with a SUMO-binding Motif (SBM) 分子名称: Protein inhibitor of activated STAT2, Small ubiquitin-related modifier 1 著者 Song, J, Zhang, Z, Hu, W, Chen, Y. 登録日 2005-08-23 公開日 2005-10-11 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Small Ubiquitin-like Modifier (SUMO) Recognition of a SUMO Binding Motif: A reversal of the bound orientation J.Biol.Chem., 280, 2005
3U5M	Crystal structure of TRIM33 PHD-Bromo in the free state 分子名称: CALCIUM ION, E3 ubiquitin-protein ligase TRIM33, ZINC ION 著者 Wang, Z, Patel, D.J. 登録日 2011-10-11 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 A poised chromatin platform for TGF-beta access to master regulators Cell(Cambridge,Mass.), 147, 2011
6DCL	Crystal structure of UP1 bound to pri-miRNA-18a terminal loop 分子名称: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3') 著者 Kooshapur, H, Sattler, M. 登録日 2018-05-07 公開日 2018-06-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.497 Å) 主引用文献 Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1. Nat Commun, 9, 2018

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