PDB: 343 件ウェブページステータス検索Chemie searchBIRD

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2GMT	THREE-DIMENSIONAL STRUCTURE OF CHYMOTRYPSIN INACTIVATED WITH (2S) N-ACETYL-L-ALANYL-L-PHENYLALANYL-CHLOROETHYL KETONE: IMPLICATIONS FOR THE MECHANISM OF INACTIVATION OF SERINE PROTEASES BY CHLOROKETONES 分子名称: (2S) N-ACETYL-L-ALANYL-ALPHAL-PHENYLALANYL-CHLOROETHYLKETONE, GAMMA-CHYMOTRYPSIN 著者 Kreutter, K, Steinmetz, A.C.U, Liang, T.-C, Prorok, M, Abeles, R, Ringe, D. 登録日 1994-09-07 公開日 1994-11-01 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones. Biochemistry, 33, 1994
1ACB	CRYSTAL AND MOLECULAR STRUCTURE OF THE BOVINE ALPHA-CHYMOTRYPSIN-EGLIN C COMPLEX AT 2.0 ANGSTROMS RESOLUTION 分子名称: ALPHA-CHYMOTRYPSIN, Eglin C 著者 Bolognesi, M, Frigerio, F, Coda, A, Pugliese, L, Lionetti, C, Menegatti, E, Amiconi, G, Schnebli, H.P, Ascenzi, P. 登録日 1991-11-08 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal and molecular structure of the bovine alpha-chymotrypsin-eglin c complex at 2.0 A resolution. J.Mol.Biol., 225, 1992
6XJA	Streptococcus Pneumoniae IgA1 Protease with IgA1 substrate 分子名称: Immunoglobulin A1 protease, Immunoglobulin alpha-1 heavy chain, Immunoglobulin alpha-1 light chain, ... 著者 Eisenmesser, E.Z, Zheng, H. 登録日 2020-06-23 公開日 2021-01-20 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease. Nat Commun, 11, 2020
6XRE	Structure of the p53/RNA polymerase II assembly 分子名称: Cellular tumor antigen p53, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 Liou, S.-H, Singh, S, Singer, R.H, Coleman, R.A, Liu, W. 登録日 2020-07-12 公開日 2021-03-24 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structure of the p53/RNA polymerase II assembly. Commun Biol, 4, 2021
4LO9	Human p53 Core Domain Mutant N235K 分子名称: Cellular tumor antigen p53, ZINC ION 著者 Wallentine, B.D, Wang, Y, Luecke, H. 登録日 2013-07-12 公開日 2013-07-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue. Acta Crystallogr.,Sect.D, 69, 2013
3Q01	An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity 分子名称: Cellular tumor antigen p53, ZINC ION 著者 Petty, T.J, Halazonetis, T.D. 登録日 2010-12-15 公開日 2011-05-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity. Embo J., 30, 2011
3IGL	Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 1) 分子名称: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ... 著者 Kitayner, M, Suad, O, Rozenberg, H, Shakked, Z. 登録日 2009-07-28 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
3KMD	Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer 分子名称: 5'-D(*GP*GP*GP*CP*AP*TP*GP*CP*CP*TP*AP*GP*GP*CP*AP*TP*GP*CP*C)-3', Cellular tumor antigen p53, ZINC ION 著者 Chen, Y, Dey, R, Chen, L. 登録日 2009-11-10 公開日 2010-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer. Structure, 18, 2010
3KZ8	Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 3) 分子名称: Cellular tumor antigen p53, DNA (5'-D(*TP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*C)-3'), IODIDE ION, ... 著者 Rozenberg, H, Suad, O, Shakked, Z. 登録日 2009-12-08 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
4MZR	Crystal structure of a polypeptide p53 mutant bound to DNA 分子名称: Cellular tumor antigen p53, ZINC ION, consensus DNA anti-sense strand, ... 著者 Emamzadah, S.T, Tropia, L, Vincenti, I, Falquet, B, Halazonetis, T.D. 登録日 2013-09-30 公開日 2014-01-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein. J.Mol.Biol., 426, 2014
1AB9	CRYSTAL STRUCTURE OF BOVINE GAMMA-CHYMOTRYPSIN 分子名称: GAMMA-CHYMOTRYPSIN, PENTAPEPTIDE (TPGVY), SULFATE ION 著者 Sugio, S, Kashima, A, Inoue, Y, Maeda, I, Nose, T, Shimohigashi, Y. 登録日 1997-02-05 公開日 1997-08-20 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray crystal structure of a dipeptide-chymotrypsin complex in an inhibitory interaction. Eur.J.Biochem., 255, 1998
1AFQ	CRYSTAL STRUCTURE OF BOVINE GAMMA-CHYMOTRYPSIN COMPLEXED WITH A SYNTHETIC INHIBITOR 分子名称: BOVINE GAMMA-CHYMOTRYPSIN, D-leucyl-N-(4-fluorobenzyl)-L-phenylalaninamide, SULFATE ION 著者 Sugio, S, Kashima, A, Inoue, Y, Maeda, I, Nose, T, Shimohigashi, Y. 登録日 1997-03-12 公開日 1997-09-17 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal structure of a dipeptide-chymotrypsin complex in an inhibitory interaction. Eur.J.Biochem., 255, 1998
4MZI	Crystal structure of a human mutant p53 分子名称: Cellular tumor antigen p53, ZINC ION 著者 Emamzadah, S, Tropia, L, Vincenti, I, Falquet, B, Halazonetis, T.D. 登録日 2013-09-30 公開日 2014-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein. J.Mol.Biol., 426, 2014
3Q05	An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity 分子名称: Cellular tumor antigen p53, DNA (26-MER), ZINC ION 著者 Petty, T.J, Halazonetis, T.D. 登録日 2010-12-15 公開日 2011-05-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity. Embo J., 30, 2011
3Q06	An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity 分子名称: Cellular tumor antigen p53, DNA (26-MER), ZINC ION 著者 Petty, T.J, Halazonetis, T.D. 登録日 2010-12-15 公開日 2011-05-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity. Embo J., 30, 2011
8SKU	Structure of human SIgA1 in complex with human CD89 (FcaR1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... 著者 Liu, Q, Stadtmueller, B.M. 登録日 2023-04-20 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions. Nat Commun, 14, 2023
8SKV	Structure of human SIgA1 in complex with Streptococcus pyogenes protein M4 (Arp4) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgA receptor, ... 著者 Liu, Q, Stadtmueller, B.M. 登録日 2023-04-20 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions. Nat Commun, 14, 2023
5GCH	CHEMISTRY OF CAGED ENZYMES /II$. PHOTOACTIVATION OF INHIBITED CHYMOTRYPSIN 分子名称: GAMMA-CHYMOTRYPSIN A 著者 Stoddard, B.L, Ringe, D, Petsko, G.A. 登録日 1989-09-25 公開日 1990-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Photolysis and deacylation of inhibited chymotrypsin. Biochemistry, 29, 1990
5HJ0	Crystal Structure of Mis18 'Yippee-like' Domain 分子名称: Kinetochore protein mis18, ZINC ION 著者 Medina-Pritchard, B, Subramanian, L, Allshire, R, Arockia Jeyaprakash, A. 登録日 2016-01-12 公開日 2016-03-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization. Embo Rep., 17, 2016
3BYK	Crystal structure of B. subtilis levansucrase mutant D247A 分子名称: CALCIUM ION, Levansucrase 著者 Futterer, K, Meng, G. 登録日 2008-01-16 公開日 2008-02-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Donor substrate recognition in the raffinose-bound E342A mutant of fructosyltransferase Bacillus subtilis levansucrase To be Published
3BYN	Crystal structure of B. subtilis levansucrase mutant E342A bound to raffinose 分子名称: CALCIUM ION, Levansucrase, alpha-D-galactopyranose-(1-6)-alpha-D-glucopyranose-(1-2)-beta-D-fructofuranose 著者 Futterer, K, Meng, G. 登録日 2008-01-16 公開日 2008-02-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Donor substrate recognition in the raffinose-bound E342A mutant of fructosyltransferase Bacillus subtilis levansucrase To be Published
3BYJ	Crystal structure of B. subtilis levansucrase mutant D86A 分子名称: CALCIUM ION, Levansucrase 著者 Futterer, K, Meng, G. 登録日 2008-01-16 公開日 2008-02-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Donor substrate recognition in the raffinose-bound E342A mutant of fructosyltransferase Bacillus subtilis levansucrase To be Published
7QIR	CRYSTAL STRUCTURE OF THE P1 monofluorethylglycine(MfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Wahl, M.C, Loll, B. 登録日 2021-12-15 公開日 2022-03-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chem Biol, 3, 2022
7QIS	CRYSTAL STRUCTURE OF THE P1 difluoroethylglycine (DfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Wahl, M.C, Loll, B. 登録日 2021-12-15 公開日 2022-03-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chem Biol, 3, 2022
7QIT	CRYSTAL STRUCTURE OF THE P1 trifluoroethylglycine (TfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Wahl, M.C, Loll, B. 登録日 2021-12-15 公開日 2022-03-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chem Biol, 3, 2022

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