PDB: 297 件ウェブページステータス検索Chemie searchBIRD

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3H3J	Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate 分子名称: GLYCEROL, L-lactate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Ho, M.-C, Almo, S.C, Schramm, V.L. 登録日 2009-04-16 公開日 2010-04-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate To be Published
3H3F	Rabbit muscle L-lactate dehydrogenase in complex with NADH and oxamate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ACETATE ION, L-lactate dehydrogenase A chain, ... 著者 Bujacz, A, Bujacz, G, Swiderek, K, Paneth, P. 登録日 2009-04-16 公開日 2009-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Modeling of isotope effects on binding oxamate to lactic dehydrogenase J.Phys.Chem.B, 113, 2009
4AJ2	rat LDHA in complex with 5-(2-chlorophenyl)-1H-tetrazole 分子名称: 5-(2-CHLOROPHENYL)-1H-TETRAZOLE, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G, Frazer, M. 登録日 2012-02-15 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
4AL4	rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)3-oxo-propyl)carbamoylamino)ethoxy)phenyl)methylpropanedioic acid 分子名称: 2-[[4-[2-[[3-[(2-methyl-1,3-benzothiazol-6-yl)amino]-3-oxidanylidene-propyl]carbamoylamino]ethoxy]phenyl]methyl]propanedioic acid, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN 著者 Tucker, J.A, Brassington, C, Hassall, G, Ward, R, Tart, J, Davies, G, Hohson, M, Pearson, S. 登録日 2012-03-01 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
4AJE	rat LDHA in complex with 2-(4-bromophenoxy)propanedioic acid 分子名称: 2-(4-BROMANYLPHENOXY)PROPANEDIOIC ACID, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G, Pearson, S. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
4AJO	rat LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol-6yl) amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Watson, M, Ward, R, Tart, J, Davies, G, Caputo, A, Pearson, S. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
4AJN	rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)-3-oxo-propyl)carbamoylamino)ethyl)phenyl)methyl) propanedioic acid 分子名称: (4-{2-[({3-[(2-METHYL-1,3-BENZOTHIAZOL-6-YL)AMINO]-3-OXOPROPYL}CARBAMOYL)AMINO]ETHYL}BENZYL)PROPANEDIOIC ACID, GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN 著者 Tucker, J.A, Brassington, C, Hassall, G, Watson, M, Ward, R, Tart, J, Davies, G, Caputo, A, Pearson, S. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
4AJI	rat LDHA in complex with 2-((3,4-dimethoxyphenyl)methyl))propanedioic acid 分子名称: 2-((3,4-DIMETHOXYPHENYL)METHYL))PROPANEDIOIC ACID, L-LACTATE DEHYDROGENASE A CHAIN 著者 Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G, Debreczeni, J. 登録日 2012-02-16 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
1IZ9	Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8 分子名称: MALATE DEHYDROGENASE 著者 Hirose, R, Hasegawa, T, Yamano, A, Kuramitsu, S, Hamada, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2002-10-01 公開日 2002-10-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Malate Dehydrogenase from Thermus themrophilus HB8 To be published
4BGU	1.50 A resolution structure of the malate dehydrogenase from Haloferax volcanii 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, ... 著者 Talon, R, Madern, D, Girard, E. 登録日 2013-03-28 公開日 2014-04-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.487 Å) 主引用文献 Insight Into Structural Evolution of Extremophilic Proteins To be Published
4B7U	PLASMODIUM FALCIPARUM L-LACTATE DEHYDROGENASE COMPLEXED WITH BICINE 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, BICINE, ... 著者 Birkinshaw, R.W, Brady, R.L. 登録日 2012-08-22 公開日 2012-10-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The Crystal Structure of Plasmodium Falciparum L- Lactate Dehydrogenase in Complex with a Novel Bicine Ligand To be Published
4BGV	1.8 A resolution structure of the malate dehydrogenase from Picrophilus torridus in its apo form 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Talon, R, Madern, D, Girard, E. 登録日 2013-03-28 公開日 2014-04-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.811 Å) 主引用文献 Insight Into Structural Evolution of Extremophilic Proteins To be Published
1IE3	CRYSTAL STRUCTURE OF R153C E. COLI MALATE DEHYDROGENASE 分子名称: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID 著者 Bell, J.K, Yennawar, H.P, Wright, S.K, Thompson, J.R, Viola, R.E, Banaszak, L.J. 登録日 2001-04-05 公開日 2001-09-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Analyses of a Malate Dehydrogenase with a Variable Active Site J.Biol.Chem., 276, 2001
4CL3	1.70 A resolution structure of the malate dehydrogenase from Chloroflexus aurantiacus 分子名称: ACETATE ION, CADMIUM ION, CHLORIDE ION, ... 著者 Talon, R, Madern, D, Girard, E. 登録日 2014-01-11 公開日 2014-02-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 An Experimental Point of View on Hydration/Solvation in Halophilic Proteins. Front.Microbiol., 5, 2014
4E0B	2.17 Angstrom resolution crystal structure of malate dehydrogenase from Vibrio vulnificus CMCP6 分子名称: ACETATE ION, Malate dehydrogenase 著者 Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-03-02 公開日 2012-03-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 2.17 Angstrom resolution crystal structure of malate dehydrogenase from Vibrio vulnificus CMCP6 To be Published
1LLD	MOLECULAR BASIS OF ALLOSTERIC ACTIVATION OF BACTERIAL L-LACTATE DEHYDROGENASE 分子名称: L-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Iwata, S, Ohta, T. 登録日 1992-06-08 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis of allosteric activation of bacterial L-lactate dehydrogenase. J.Mol.Biol., 230, 1993
1LDN	STRUCTURE OF A TERNARY COMPLEX OF AN ALLOSTERIC LACTATE DEHYDROGENASE FROM BACILLUS STEAROTHERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, L-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Wigley, D.B, Gamblin, S.J, Turkenburg, J.P, Dodson, E.J, Piontek, K, Muirhead, H, Holbrook, J.J. 登録日 1991-11-19 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of a ternary complex of an allosteric lactate dehydrogenase from Bacillus stearothermophilus at 2.5 A resolution. J.Mol.Biol., 223, 1992
1LDM	Refined crystal structure of dogfish M4 apo-lactate dehydrogenase 分子名称: M4 LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID 著者 Griffith, J.P, Rossmann, M.G. 登録日 1987-11-25 公開日 1989-07-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Refined crystal structure of dogfish M4 apo-lactate dehydrogenase. J.Mol.Biol., 198, 1987
1LLC	STRUCTURE DETERMINATION OF THE ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS CASEI AT 3.0 ANGSTROMS RESOLUTION 分子名称: 1,6-di-O-phosphono-alpha-D-fructofuranose, L-LACTATE DEHYDROGENASE, SULFATE ION 著者 Buehner, M, Hecht, H.J, Hensel, R. 登録日 1988-11-21 公開日 1989-07-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 STRUCTURE DETERMINATION OF THE ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS-CASEI AT 3A RESOLUTION. Acta Crystallogr.,Sect.A, 40, 1984
1LTH	T AND R STATES IN THE CRYSTALS OF BACTERIAL L-LACTATE DEHYDROGENASE REVEAL THE MECHANISM FOR ALLOSTERIC CONTROL 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, L-LACTATE DEHYDROGENASE (T- AND R- STATE TETRAMER COMPLEX), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Iwata, S, Ohta, T. 登録日 1995-01-04 公開日 1995-03-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 T and R states in the crystals of bacterial L-lactate dehydrogenase reveal the mechanism for allosteric control. Nat.Struct.Biol., 1, 1994
1LDB	STRUCTURE DETERMINATION AND REFINEMENT OF BACILLUS STEAROTHERMOPHILUS LACTATE DEHYDROGENASE 分子名称: APO-L-LACTATE DEHYDROGENASE, SULFATE ION 著者 Piontek, K, Rossmann, M.G. 登録日 1989-03-27 公開日 1989-07-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure determination and refinement of Bacillus stearothermophilus lactate dehydrogenase. Proteins, 7, 1990
1LDG	PLASMODIUM FALCIPARUM L-LACTATE DEHYDROGENASE COMPLEXED WITH NADH AND OXAMATE 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-LACTATE DEHYDROGENASE, OXAMIC ACID 著者 Dunn, C, Banfield, M, Barker, J, Higham, C, Moreton, K, Turgut-Balik, D, Brady, L, Holbrook, J.J. 登録日 1996-09-10 公開日 1997-09-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 The structure of lactate dehydrogenase from Plasmodium falciparum reveals a new target for anti-malarial design. Nat.Struct.Biol., 3, 1996
1MLD	REFINED STRUCTURE OF MITOCHONDRIAL MALATE DEHYDROGENASE FROM PORCINE HEART AND THE CONSENSUS STRUCTURE FOR DICARBOXYLIC ACID OXIDOREDUCTASES 分子名称: CITRIC ACID, MALATE DEHYDROGENASE 著者 Gleason, W.B, Fu, Z, Birktoft, J.J, Banaszak, L.J. 登録日 1994-01-24 公開日 1995-01-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Refined crystal structure of mitochondrial malate dehydrogenase from porcine heart and the consensus structure for dicarboxylic acid oxidoreductases. Biochemistry, 33, 1994
1OC4	Lactate dehydrogenase from Plasmodium berghei 分子名称: GLYCEROL, L-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Winter, V.J, Brady, R.L. 登録日 2003-02-05 公開日 2003-09-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of Plasmodium Berghei Lactate Dehydrogenase Indicates the Unique Structural Differences of These Enzymes are Shared Across the Plasmodium Genus Mol.Biochem.Parasitol., 131, 2003
6BAX	Lactate Dehydrogenase in complex with inhibitor 6-(3-aminophenyl)-3-((2-chlorophenyl)thio)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one 分子名称: (6R)-6-(3-aminophenyl)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, L-lactate dehydrogenase A chain, ... 著者 Ultsch, M, Eigenbrot, C. 登録日 2017-10-16 公開日 2018-10-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure-guided optimization and in vivo activities of hydroxylactone and hydroxylactam Inhibitors of Human Lactate Dehydrogenase To Be Published

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