3NMX
 
 | | Crystal structure of APC complexed with Asef | | 分子名称: | APC variant protein, Rho guanine nucleotide exchange factor 4 | | 著者 | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | 登録日 | 2010-06-22 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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6BWB
 | | Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3 | | 分子名称: | Importin subunit alpha-3, Protein W | | 著者 | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | 登録日 | 2017-12-14 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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1QGR
 | | STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA (II CRYSTAL FORM, GROWN AT LOW PH) | | 分子名称: | PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT) | | 著者 | Cingolani, G, Petosa, C, Weis, K, Muller, C.W. | | 登録日 | 1999-05-04 | | 公開日 | 1999-05-24 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
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6BVZ
 | | Importin alpha 3 in cargo free state | | 分子名称: | Importin subunit alpha-3 | | 著者 | Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | 登録日 | 2017-12-14 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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3ZIR
 | | minor-site specific NLS (B141) | | 分子名称: | B141NLS, IMPORTIN SUBUNIT ALPHA-2 | | 著者 | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | | 登録日 | 2013-01-10 | | 公開日 | 2013-08-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
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6D7N
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1Q1S
 | | Mouse Importin alpha- phosphorylated SV40 CN peptide complex | | 分子名称: | Importin alpha-2 subunit, Large T antigen | | 著者 | Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. | | 登録日 | 2003-07-22 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
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5E6Q
 | | Importin alpha binding to XRCC1 NLS peptide | | 分子名称: | CHLORIDE ION, DNA repair protein XRCC1 NLS peptide, GLYCEROL, ... | | 著者 | Pedersen, L.C, Kirby, T.W, Gassman, N.R, Smith, C.E, Gabel, S.A, Sobhany, M, Wilson, S.H, London, R.E. | | 登録日 | 2015-10-10 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.305 Å) | | 主引用文献 | Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS.
Sci Rep, 5, 2015
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4U5N
 | | IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR | | 分子名称: | Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide | | 著者 | Stewart, M, Valkov, E, Holvey, R.S. | | 登録日 | 2014-07-25 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
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7UWI
 | | Structure of beta-catenin in complex with FP01567, a Helicon Polypeptide | | 分子名称: | Catenin beta-1, GLYCEROL, Helicon Polypeptide FP01567, ... | | 著者 | Brennan, M, Agarwal, S, Thomson, T, Wahl, S, Ramirez, J, Verdine, G, McGee, J. | | 登録日 | 2022-05-03 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
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4EVT
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8G4J
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3UKY
 | | Mouse importin alpha: yeast CBP80 cNLS complex | | 分子名称: | Importin subunit alpha-2, Nuclear cap-binding protein complex subunit 1 | | 著者 | Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. | | 登録日 | 2011-11-10 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
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8Z10
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2P8Q
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3UVU
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5GXW
 | | Importin and NuMA complex | | 分子名称: | Importin subunit alpha-1, Peptide from Nuclear mitotic apparatus protein 1 | | 著者 | Chang, C.-C, Huang, T.-L, Hsia, K.-C. | | 登録日 | 2016-09-20 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.394 Å) | | 主引用文献 | Regulation of mitotic spindle assembly factor NuMA by Importin-beta
J. Cell Biol., 216, 2017
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7LET
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6IWA
 | | Crystal structure of Importin-alpha and phosphoserine GM130 | | 分子名称: | Importin subunit alpha-1, PHOSPHOSERINE GM130 | | 著者 | Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C. | | 登録日 | 2018-12-05 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha.
Nat Commun, 10, 2019
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3L6X
 | | Crystal structure of p120 catenin in complex with E-cadherin | | 分子名称: | Catenin delta-1, E-cadherin, SULFATE ION | | 著者 | Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M. | | 登録日 | 2009-12-27 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Cell(Cambridge,Mass.), 141, 2010
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1EE5
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8SG7
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5K9S
 | | Importin-alpha in complex with HNF1-beta peptide | | 分子名称: | HNF1 beta A splice variant 2, Importin subunit alpha-1 | | 著者 | Wiedmann, M.M, Aibara, S, Spring, D.R, Stewart, M, Brenton, J. | | 登録日 | 2016-06-01 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Importin-alpha in complex with HNF1-beta peptide
To Be Published
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3OUX
 | | Structure of beta-catenin with phosphorylated Lef-1 | | 分子名称: | Catenin beta-1, Lymphoid enhancer-binding factor 1 | | 著者 | Weis, W.I, Sun, J. | | 登録日 | 2010-09-15 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Biochemical and structural characterization of beta-catenin interactions with nonphosphorylated and CK2-phosphorylated Lef-1.
J.Mol.Biol., 405, 2011
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5XJG
 | | Crystal structure of Vac8p bound to Nvj1p | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Nucleus-vacuole junction protein 1, ... | | 著者 | Jeong, H, Park, J, Jun, Y, Lee, C. | | 登録日 | 2017-05-01 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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