PDB: 430 件ウェブページステータス検索Chemie searchBIRD

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6ZHU	Yeast Uba1 in complex with Ubc3 and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ubiquitin-activating enzyme E1 1, ... 著者 Misra, M, Schindelin, H. 登録日 2020-06-23 公開日 2022-01-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system To Be Published
1TTE	The Structure of a Class II ubiquitin-conjugating enzyme, Ubc1. 分子名称: Ubiquitin-conjugating enzyme E2-24 kDa 著者 Merkley, N, Shaw, G.S. 登録日 2004-06-22 公開日 2004-08-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the flexible class II ubiquitin-conjugating enzyme Ubc1 provides insights for polyubiquitin chain assembly. J.Biol.Chem., 279, 2004
6GUM	Structure of the A.thaliana E1 UFD domain in complex with E2 分子名称: GLYCEROL, SAE2, SUMO-conjugating enzyme SCE1 著者 Liu, B, Lois, L.M, Reverter, D. 登録日 2018-06-19 公開日 2019-07-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.792 Å) 主引用文献 Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution. Biochem.J., 476, 2019
7UN6	Complex of UBE2O with NAP1L1 分子名称: (E3-independent) E2 ubiquitin-conjugating enzyme, Nucleosome assembly protein 1-like 1 著者 Yip, M.C.J, Sedor, S.F, Shao, S. 登録日 2022-04-09 公開日 2022-08-03 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mechanism of client selection by the protein quality-control factor UBE2O. Nat.Struct.Mol.Biol., 29, 2022
6XOD	Crystal structure of the PEX4-PEX22 protein complex from Arabidopsis thaliana 分子名称: Peroxisome biogenesis protein 22, Protein PEROXIN-4 著者 Olmos Jr, J.L, Bradford, S.E, Miller, M.D, Xu, W, Wright, Z.J, Bartel, B, Phillips Jr, G.N. 登録日 2020-07-06 公開日 2021-07-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 The Structure of the Arabidopsis PEX4-PEX22 Peroxin Complex-Insights Into Ubiquitination at the Peroxisomal Membrane Front Cell Dev Biol, 10, 2022
6HPR	Crystal structure of cIAP1 RING domain bound to UbcH5B-Ub and a non-covalent Ub 分子名称: Baculoviral IAP repeat-containing protein 2, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Patel, A, Huang, D.T. 登録日 2018-09-21 公開日 2018-12-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex. J. Biol. Chem., 294, 2019
8GCB	Structure of RNF125 in complex with a UbcH5b~Ub conjugate 分子名称: E3 ubiquitin-protein ligase RNF125, Ubiquitin-conjugating enzyme E2 D2, ZINC ION 著者 Middleton, A.J, Day, C.L, Fokkens, T.J. 登録日 2023-03-01 公開日 2023-07-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation. Structure, 31, 2023
8GBQ	Structure of RNF125 in complex with UbcH5b 分子名称: E3 ubiquitin-protein ligase RNF125, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Middleton, A.J, Day, C.L, Fokkens, T.J. 登録日 2023-02-27 公開日 2023-07-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation. Structure, 31, 2023
7UN3	Complex of UBE2O with NAP1L1 and ubiquitylated uL2 分子名称: Nucleosome assembly protein 1-like 1, Ubiquitin,60S ribosomal protein L8,(E3-independent) E2 ubiquitin-conjugating enzyme fusion 著者 Yip, M.C.J, Sedor, S.F, Shao, S. 登録日 2022-04-08 公開日 2022-08-03 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanism of client selection by the protein quality-control factor UBE2O. Nat.Struct.Mol.Biol., 29, 2022
1UR6	NMR based structural model of the UbcH5B-CNOT4 complex 分子名称: POTENTIAL TRANSCRIPTIONAL REPRESSOR NOT4HP, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA 2, ZINC ION 著者 Dominguez, C, Bonvin, A.M.J.J, Winkler, G.S, Van Schaik, F.M.A, Timmers, H.Th.M, Boelens, R. 登録日 2003-10-27 公開日 2004-05-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR, THEORETICAL MODEL 主引用文献 Structural Model of the Ubch5B/Cnot4 Complex Revealed by Combining NMR, Mutagenesis, and Docking Approaches. Structure, 12, 2004
7AI0	Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 1) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ... 著者 Magnussen, H.M, Huang, D.T. 登録日 2020-09-25 公開日 2021-01-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.559 Å) 主引用文献 Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. J.Mol.Biol., 433, 2021
7AHZ	Crystal structure of Western clawed frog MDM2 RING domain homodimer bound to UbcH5B-Ub 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, ... 著者 Magnussen, H.M, Huang, D.T. 登録日 2020-09-25 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. J.Mol.Biol., 433, 2021
7AI1	Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 2) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ... 著者 Magnussen, H.M, Huang, D.T. 登録日 2020-09-25 公開日 2021-01-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. J.Mol.Biol., 433, 2021
7BBF	Crystal structure of ubiquitin charged Ube2N (Ube2N~Ub) in complex with Ube2V2 分子名称: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 著者 Kiss, L, Neuhaus, D, James, L.C. 登録日 2020-12-17 公開日 2021-01-27 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination. Nat Commun, 12, 2021
6N13	UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin 分子名称: E3 ubiquitin-protein ligase parkin, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ... 著者 Condos, T.E.C, Dunkerley, K.M, Freeman, E.A, Barber, K.R, Aguirre, J.D, Chaugule, V.K, Xiao, Y, Konermann, L, Walden, H, Shaw, G.S. 登録日 2018-11-08 公開日 2018-11-28 最終更新日 2020-01-08 実験手法 SOLUTION NMR 主引用文献 Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation. EMBO J., 37, 2018
4JQU	Crystal structure of Ubc7p in complex with the U7BR of Cue1p 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coupling of ubiquitin conjugation to ER degradation protein 1, DI(HYDROXYETHYL)ETHER, ... 著者 Liang, Y.-H, Metzger, M.B, Weissman, A.M, Ji, X. 登録日 2013-03-20 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms. Mol.Cell, 50, 2013
6NYA	Crystal Structure of ubiquitin E1 (Uba1) in complex with Ubc3 (Cdc34) and ubiquitin 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Olsen, S.K, Williams, K.M, Atkison, J.H. 登録日 2019-02-11 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.065 Å) 主引用文献 Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34. Nat Commun, 10, 2019
6NYO	Crystal structure of a human Cdc34-ubiquitin thioester mimetic 分子名称: 1,2-ETHANEDIOL, 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, PHOSPHATE ION, ... 著者 Olsen, S.K, Williams, K.M, Atkison, J.H. 登録日 2019-02-11 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.502 Å) 主引用文献 Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34. Nat Commun, 10, 2019
7XED	Crystal Structure of OsCIE1-Ubox and OsUBC8 complex 分子名称: U-box domain-containing protein 12, UBC core domain-containing protein 著者 Zhang, Y, Yu, C.Z. 登録日 2022-03-30 公開日 2023-10-04 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Release of a ubiquitin brake activates OsCERK1-triggered immunity in rice. Nature, 629, 2024
2UYZ	Non-covalent complex between Ubc9 and SUMO1 分子名称: SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, SUMO-CONJUGATING ENZYME UBC9 著者 Knipscheer, P, van Dijk, W.J, Olsen, J.V, Mann, M, Sixma, T.K. 登録日 2007-04-21 公開日 2007-06-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation. EMBO J., 26, 2007
4IP3	Complex structure of OspI and Ubc13 分子名称: ORF169b, Ubiquitin-conjugating enzyme E2 N 著者 Fu, P, Jin, M, Zhang, X, Xu, L, Xia, Z, Zhu, Y. 登録日 2013-01-09 公開日 2013-03-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure Analysis of Ubc13 Inactivation To be Published
2VRR	Structure of SUMO modified Ubc9 分子名称: FORMIC ACID, SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, ... 著者 Knipscheer, P, Flotho, A, Klug, H, Olsen, J.V, van Dijk, W.J, Fish, A, Johnson, E.S, Mann, M, Sixma, T.K, Pichler, A. 登録日 2008-04-13 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Ubc9 sumoylation regulates SUMO target discrimination. Mol. Cell, 31, 2008
7BXG	MavC-UBE2N-Ub complex 分子名称: MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N 著者 Gao, P, Wang, Y. 登録日 2020-04-19 公開日 2020-05-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.705 Å) 主引用文献 Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
4II2	Crystal structure of Ubiquitin activating enzyme 1 (Uba1) in complex with the Ub E2 Ubc4, ubiquitin, and ATP/Mg 分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Olsen, S.K, Lima, C.D. 登録日 2012-12-19 公開日 2013-02-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer. Mol.Cell, 49, 2013
4LDT	The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ... 著者 Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C. 登録日 2013-06-25 公開日 2013-08-14 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1. Nat.Struct.Mol.Biol., 20, 2013

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