PDB: 424 件ウェブページステータス検索Chemie searchBIRD

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4IP3	Complex structure of OspI and Ubc13 分子名称: ORF169b, Ubiquitin-conjugating enzyme E2 N 著者 Fu, P, Jin, M, Zhang, X, Xu, L, Xia, Z, Zhu, Y. 登録日 2013-01-09 公開日 2013-03-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure Analysis of Ubc13 Inactivation To be Published
1TTE	The Structure of a Class II ubiquitin-conjugating enzyme, Ubc1. 分子名称: Ubiquitin-conjugating enzyme E2-24 kDa 著者 Merkley, N, Shaw, G.S. 登録日 2004-06-22 公開日 2004-08-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the flexible class II ubiquitin-conjugating enzyme Ubc1 provides insights for polyubiquitin chain assembly. J.Biol.Chem., 279, 2004
7UN6	Complex of UBE2O with NAP1L1 分子名称: (E3-independent) E2 ubiquitin-conjugating enzyme, Nucleosome assembly protein 1-like 1 著者 Yip, M.C.J, Sedor, S.F, Shao, S. 登録日 2022-04-09 公開日 2022-08-03 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mechanism of client selection by the protein quality-control factor UBE2O. Nat.Struct.Mol.Biol., 29, 2022
7UN3	Complex of UBE2O with NAP1L1 and ubiquitylated uL2 分子名称: Nucleosome assembly protein 1-like 1, Ubiquitin,60S ribosomal protein L8,(E3-independent) E2 ubiquitin-conjugating enzyme fusion 著者 Yip, M.C.J, Sedor, S.F, Shao, S. 登録日 2022-04-08 公開日 2022-08-03 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanism of client selection by the protein quality-control factor UBE2O. Nat.Struct.Mol.Biol., 29, 2022
4JQU	Crystal structure of Ubc7p in complex with the U7BR of Cue1p 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coupling of ubiquitin conjugation to ER degradation protein 1, DI(HYDROXYETHYL)ETHER, ... 著者 Liang, Y.-H, Metzger, M.B, Weissman, A.M, Ji, X. 登録日 2013-03-20 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms. Mol.Cell, 50, 2013
3OJ4	Crystal structure of the A20 ZnF4, ubiquitin and UbcH5A complex 分子名称: Tumor necrosis factor alpha-induced protein 3, Ubiquitin, Ubiquitin-conjugating enzyme E2 D1, ... 著者 Bosanac, I, Hymowitz, S.G. 登録日 2010-08-20 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling Mol.Cell, 40, 2010
1UR6	NMR based structural model of the UbcH5B-CNOT4 complex 分子名称: POTENTIAL TRANSCRIPTIONAL REPRESSOR NOT4HP, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA 2, ZINC ION 著者 Dominguez, C, Bonvin, A.M.J.J, Winkler, G.S, Van Schaik, F.M.A, Timmers, H.Th.M, Boelens, R. 登録日 2003-10-27 公開日 2004-05-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR, THEORETICAL MODEL 主引用文献 Structural Model of the Ubch5B/Cnot4 Complex Revealed by Combining NMR, Mutagenesis, and Docking Approaches. Structure, 12, 2004
4II2	Crystal structure of Ubiquitin activating enzyme 1 (Uba1) in complex with the Ub E2 Ubc4, ubiquitin, and ATP/Mg 分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Olsen, S.K, Lima, C.D. 登録日 2012-12-19 公開日 2013-02-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer. Mol.Cell, 49, 2013
3PTF	X-ray structure of the non-covalent complex between UbcH5A and Ubiquitin 分子名称: Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D1 著者 Bosanac, I, Hymowitz, S.G. 登録日 2010-12-02 公開日 2011-05-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A. J.Mol.Biol., 408, 2011
7MYF	Ubiquitin variant UbV.k.1 in complex with Ube2k 分子名称: Ubiquitin, Ubiquitin variant UbV.k.1, Ubiquitin-conjugating enzyme E2 K 著者 Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S. 登録日 2021-05-21 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k. Acs Chem.Biol., 16, 2021
7MYH	Ubiquitin variant UbV.k.2 in complex with Ube2k 分子名称: GLYCEROL, Ubiquitin variant UbV.k.2, Ubiquitin-conjugating enzyme E2 K 著者 Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S. 登録日 2021-05-21 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.394 Å) 主引用文献 Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k. Acs Chem.Biol., 16, 2021
4Y1L	Ubc9 Homodimer The Missing Link in Poly-SUMO Chain Formation 分子名称: RWD domain-containing protein 3, SUMO-conjugating enzyme UBC9 著者 Aileen, Y.A, Ambaye, N.D, Li, Y.J, Vega, R, Bzymek, K, Williams, J.C, Hu, W, Chen, Y. 登録日 2015-02-08 公開日 2015-05-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 RWD Domain as an E2 (Ubc9)-Interaction Module. J.Biol.Chem., 290, 2015
8GCB	Structure of RNF125 in complex with a UbcH5b~Ub conjugate 分子名称: E3 ubiquitin-protein ligase RNF125, Ubiquitin-conjugating enzyme E2 D2, ZINC ION 著者 Middleton, A.J, Day, C.L, Fokkens, T.J. 登録日 2023-03-01 公開日 2023-07-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation. Structure, 31, 2023
8GBQ	Structure of RNF125 in complex with UbcH5b 分子名称: E3 ubiquitin-protein ligase RNF125, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Middleton, A.J, Day, C.L, Fokkens, T.J. 登録日 2023-02-27 公開日 2023-07-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation. Structure, 31, 2023
7OJX	E2 UBE2K covalently linked to donor Ub, acceptor di-Ub, and RING E3 primed for K48-linked Ub chain synthesis 分子名称: 1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), E3 ubiquitin-protein ligase RNF38, Polyubiquitin-B, ... 著者 Majorek, K.A, Nakasone, M.A, Huang, D.T. 登録日 2021-05-17 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension. Nat.Chem.Biol., 18, 2022
2UYZ	Non-covalent complex between Ubc9 and SUMO1 分子名称: SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, SUMO-CONJUGATING ENZYME UBC9 著者 Knipscheer, P, van Dijk, W.J, Olsen, J.V, Mann, M, Sixma, T.K. 登録日 2007-04-21 公開日 2007-06-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation. EMBO J., 26, 2007
6P5B	Crystal Structure of MavC in Complex with Ub-UbE2N 分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N 著者 Puvar, K, Iyer, S, Negron Teron, K.I, Das, C. 登録日 2019-05-30 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
2VRR	Structure of SUMO modified Ubc9 分子名称: FORMIC ACID, SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, ... 著者 Knipscheer, P, Flotho, A, Klug, H, Olsen, J.V, van Dijk, W.J, Fish, A, Johnson, E.S, Mann, M, Sixma, T.K, Pichler, A. 登録日 2008-04-13 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Ubc9 sumoylation regulates SUMO target discrimination. Mol. Cell, 31, 2008
7XED	Crystal Structure of OsCIE1-Ubox and OsUBC8 complex 分子名称: U-box domain-containing protein 12, UBC core domain-containing protein 著者 Zhang, Y, Yu, C.Z. 登録日 2022-03-30 公開日 2023-10-04 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Release of a ubiquitin brake activates OsCERK1-triggered immunity in rice. Nature, 629, 2024
7P47	Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic 分子名称: E3 SUMO-protein ligase MMS21, SUMO-conjugating enzyme UBC9, Structural maintenance of chromosomes protein 5, ... 著者 Lascorz, J, Varejao, N, Reverter, D. 登録日 2021-07-09 公開日 2021-11-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.314 Å) 主引用文献 Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs. Nat Commun, 12, 2021
4X57	Structure of an Arabidopsis E2 / Membrane-anchored Ubiquitin-fold Protein Complex 分子名称: Membrane-anchored ubiquitin-fold protein 3, SULFATE ION, Ubiquitin-conjugating enzyme E2 8 著者 Korolev, S, Koroleva, O, Lu, X, Downes, B. 登録日 2014-12-04 公開日 2016-01-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of an Arabidopsis E2 / Membrane-anchored Ubiquitin-fold ProteinComplex To Be Published
4WZ3	Crystal structure of the complex between LubX/LegU2/Lpp2887 U-box 1 and Homo sapiens UBE2D2 分子名称: E3 ubiquitin-protein ligase LubX, Ubiquitin-conjugating enzyme E2 D2 著者 Stogios, P.J, Quaile, A.T, Skarina, T, Nocek, B, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2014-11-18 公開日 2015-01-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure, 23, 2015
4YII	Structure of an APC2-UBCH10 complex reveals distinctive cullin-RING ligase mechanism for Anaphase-promoting complex/Cyclosome 分子名称: Anaphase-promoting complex subunit 2, Ubiquitin-conjugating enzyme E2 C 著者 Brown, N.G, Cho, S.E, Schulman, B.A. 登録日 2015-03-02 公開日 2015-04-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.804 Å) 主引用文献 Crystal Structure of E2 Complex Proc.Natl.Acad.Sci.USA, 2015
4WHV	E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B 分子名称: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ... 著者 Hodge, C.D, Edwards, R.A, Glover, J.N.M. 登録日 2014-09-23 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (8.3 Å) 主引用文献 RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. J.Biol.Chem., 291, 2016
2XWU	CRYSTAL STRUCTURE OF IMPORTIN 13 - UBC9 COMPLEX 分子名称: IMPORTIN13, SUMO-CONJUGATING ENZYME UBC9 著者 Gruenwald, M, Bono, F. 登録日 2010-11-05 公開日 2010-12-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of Importin13-Ubc9 Complex: Nuclear Import and Release of a Key Regulator of Sumoylation. Embo J., 30, 2011

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