1FJM
 
 | | Protein serine/threonine phosphatase-1 (alpha isoform, type 1) complexed with microcystin-LR toxin | | 分子名称: | BETA-MERCAPTOETHANOL, MANGANESE (II) ION, PROTEIN SERINE/THREONINE PHOSPHATASE-1 (ALPHA ISOFORM, ... | | 著者 | Goldberg, J, Nairn, A.C, Kuriyan, J. | | 登録日 | 1995-12-17 | | 公開日 | 1996-06-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
Nature, 376, 1995
|
|
4V0W
 | | The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-669) | | 分子名称: | MANGANESE (II) ION, PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | | 著者 | Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J. | | 登録日 | 2014-09-18 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Elife, 4, 2015
|
|
1OI8
 | | 5'-Nucleotidase (E. coli) with an Engineered Disulfide Bridge (P90C, L424C) | | 分子名称: | CARBONATE ION, MANGANESE (II) ION, PROTEIN USHA, ... | | 著者 | Schultz-Heienbrok, R, Maier, T, Straeter, N. | | 登録日 | 2003-06-10 | | 公開日 | 2004-06-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Trapping a 96 Degree Domain Rotation in Two Distinct Conformations by Engineered Disulfide Bridges
Protein Sci., 13, 2004
|
|
4WWL
 | | E. coli 5'-nucleotidase mutant I521C labeled with MTSL (intermediate form) | | 分子名称: | CARBONATE ION, GLYCEROL, Protein UshA, ... | | 著者 | Krug, U, Paithankar, K.S, Schultz-Heienbrok, R, Strater, N. | | 登録日 | 2014-11-11 | | 公開日 | 2014-11-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | E. coli 5'-nucleotidase mutant I521C labeled with MTSL (intermediate form)
To Be Published
|
|
1HPU
 | | 5'-NUCLEOTIDASE (CLOSED FORM), COMPLEX WITH AMPCP | | 分子名称: | 5'-NUCLEOTIDASE, MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | | 著者 | Knoefel, T, Straeter, N. | | 登録日 | 2000-12-13 | | 公開日 | 2002-03-20 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Mechanism of hydrolysis of phosphate esters by the dimetal center of 5'-nucleotidase based on crystal structures.
J.Mol.Biol., 309, 2001
|
|
1HO5
 | |
1HP1
 | | 5'-NUCLEOTIDASE (OPEN FORM) COMPLEX WITH ATP | | 分子名称: | 5'-NUCLEOTIDASE, ADENOSINE-5'-TRIPHOSPHATE, CARBONATE ION, ... | | 著者 | Knoefel, T, Straeter, N. | | 登録日 | 2000-12-12 | | 公開日 | 2002-03-20 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of hydrolysis of phosphate esters by the dimetal center of 5'-nucleotidase based on crystal structures.
J.Mol.Biol., 309, 2001
|
|
1OIE
 | |
1OID
 | |
1KBP
 | | KIDNEY BEAN PURPLE ACID PHOSPHATASE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FE (III) ION, PURPLE ACID PHOSPHATASE, ... | | 著者 | Klabunde, T, Strater, N, Krebs, B. | | 登録日 | 1995-02-20 | | 公開日 | 1996-10-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Mechanism of Fe(III)-Zn(II) purple acid phosphatase based on crystal structures.
J.Mol.Biol., 259, 1996
|
|
1JK7
 | | CRYSTAL STRUCTURE OF THE TUMOR-PROMOTER OKADAIC ACID BOUND TO PROTEIN PHOSPHATASE-1 | | 分子名称: | BETA-MERCAPTOETHANOL, MANGANESE (II) ION, OKADAIC ACID, ... | | 著者 | Maynes, J.T, Bateman, K.S, Cherney, M.M, Das, A.K, James, M.N. | | 登録日 | 2001-07-11 | | 公開日 | 2001-08-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1.
J.Biol.Chem., 276, 2001
|
|
1IT6
 | | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CALYCULIN A AND THE CATALYTIC SUBUNIT OF PROTEIN PHOSPHATASE 1 | | 分子名称: | CALYCULIN A, MANGANESE (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE 1 GAMMA (PP1-GAMMA) CATALYTIC SUBUNIT | | 著者 | Kita, A, Matsunaga, S, Takai, A, Kataiwa, H, Wakimoto, T, Fusetani, N, Isobe, M, Miki, K. | | 登録日 | 2002-01-09 | | 公開日 | 2002-05-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1.
Structure, 10, 2002
|
|
1MF8
 | |
1M63
 | | Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes | | 分子名称: | CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CYCLOSPORIN A, ... | | 著者 | Huai, Q, Kim, H.-Y, Liu, Y, Zhao, Y, Mondragon, A, Liu, J.O, Ke, H. | | 登録日 | 2002-07-12 | | 公開日 | 2002-09-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
7QGM
 | |
7ZR1
 | | Chaetomium thermophilum Mre11-Rad50-Nbs1 complex bound to ATPyS (composite structure) | | 分子名称: | DH domain-containing protein, Double-strand break repair protein, FHA domain-containing protein, ... | | 著者 | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | | 登録日 | 2022-05-03 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
|
|
7QGA
 | |
7QGO
 | | Human CD73 (ecto 5'-nucleotidase) in complex with MRS4602 (a 3-methyl-CMPCP derivative, compound 21 in paper) in the closed state (crystal form III) | | 分子名称: | 5'-nucleotidase, ZINC ION, [[(2~{R},3~{S},4~{R},5~{R})-5-[(4~{E})-4-[(4-methoxycarbonylphenyl)methoxyimino]-3-methyl-2-oxidanylidene-pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]methylphosphonic acid | | 著者 | Strater, N. | | 登録日 | 2021-12-09 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Structure-Activity Relationship of 3-Methylcytidine-5'-alpha , beta-methylenediphosphates as CD73 Inhibitors.
J.Med.Chem., 65, 2022
|
|
7QGL
 | |
7QM2
 | |
7QFB
 | | Crystal structure of Protein Phosphatase 1 in complex with PP1-binding peptide from PTG | | 分子名称: | GLYCEROL, MANGANESE (II) ION, Protein phosphatase 1 regulatory subunit 3C, ... | | 著者 | Semrau, M.S, Storici, P, Lolli, G. | | 登録日 | 2021-12-05 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Molecular architecture of the glycogen- committed PP1/PTG holoenzyme.
Nat Commun, 13, 2022
|
|
8A8F
 | | Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2 | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, RNA end formation protein 2, ... | | 著者 | Carminati, M, Manav, C.M, Bellini, D, Passmore, L.A. | | 登録日 | 2022-06-22 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A direct interaction between CPF and RNA Pol II links RNA 3' end processing to transcription.
Mol.Cell, 83, 2023
|
|
7QWJ
 | |
2BDX
 | | X-ray Crystal Structure of dihydromicrocystin-LA bound to Protein Phosphatase-1 | | 分子名称: | DIHYDROMICROCYSTIN-LA, MANGANESE (II) ION, Serine/threonine protein phosphatase PP1-gamma catalytic subunit | | 著者 | Maynes, J.T, Luu, H.A, Cherney, M.M, Andersen, R.J, Williams, D, Holmes, C.F, James, M.N. | | 登録日 | 2005-10-21 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of Protein Phosphatase-1 Bound to Motuporin and Dihydromicrocystin-LA: Elucidation of the Mechanism of Enzyme Inhibition by Cyanobacterial Toxins.
J.Mol.Biol., 356, 2006
|
|
8BAH
 | | Human Mre11-Nbs1 complex | | 分子名称: | Double-strand break repair protein MRE11, MANGANESE (II) ION, Nibrin | | 著者 | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | | 登録日 | 2022-10-11 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | | 主引用文献 | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
|
|
