PDB: 277 件ウェブページステータス検索Chemie searchBIRD

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6LDI	The cryo-EM structure of E. coli CueR transcription activation complex 分子名称: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Fang, C.L, Zhang, Y. 登録日 2019-11-21 公開日 2020-09-30 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.69 Å) 主引用文献 CueR activates transcription through a DNA distortion mechanism. Nat.Chem.Biol., 17, 2021
7X74	Cryo-EM structure of Streptomyces coelicolor transcription initial complex with two Zur dimers. 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2022-03-09 公開日 2022-08-03 最終更新日 2022-12-14 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
6PSW	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPo) with TraR and rpsT P2 promoter 分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-07-13 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6N57	Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation I 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2018-11-21 公開日 2020-02-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
7MKE	Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Saecker, R.M, Darst, S.A, Chen, J. 登録日 2021-04-23 公開日 2021-09-29 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
4YG2	X-ray crystal structur of Escherichia coli RNA polymerase sigma70 holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S. 登録日 2015-02-25 公開日 2015-03-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 X-ray crystal structure of Escherichia coli RNA polymerase sigma70 holoenzyme J. Biol. Chem., 288, 2013
7YE1	The cryo-EM structure of C. crescentus GcrA-TACup 分子名称: Cell cycle regulatory protein GcrA, DNA (57-MER)-non template, DNA (57-MER)-template, ... 著者 Wu, X.X, Zhang, Y. 登録日 2022-07-05 公開日 2023-01-18 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
4XSX	Crystal structure of CBR 703 bound to Escherichia coli RNA polymerase holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Bae, B, Darst, S.A. 登録日 2015-01-22 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.708 Å) 主引用文献 CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition. Proc.Natl.Acad.Sci.USA, 112, 2015
6VVZ	Mycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with Sorangicin 分子名称: DNA (62-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Boyaci, H, Chen, J, Darst, S.A, Campbell, E.A. 登録日 2020-02-18 公開日 2020-10-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.72 Å) 主引用文献 The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
5UH5	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-10 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.746 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
7MLJ	Crystal structure of Thermus thermophilus reiterative transcription complex with 4nt oligo-G RNA 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*GP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*GP*CP*CP*CP*TP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, Y, Ebright, R.H. 登録日 2021-04-28 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.75 Å) 主引用文献 Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
7VPD	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with one Zur dimers 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2021-10-15 公開日 2022-08-03 最終更新日 2022-08-24 実験手法 ELECTRON MICROSCOPY (3.77 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
5VT0	Escherichia coli 6S RNA derivative in complex with Escherichia coli RNA polymerase sigma70-holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Chen, J, Darst, S.A. 登録日 2017-05-15 公開日 2017-11-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase. Mol. Cell, 68, 2017
6N58	Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation II 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2018-11-21 公開日 2020-02-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6K4Y	CryoEM structure of sigma appropriation complex 分子名称: 10 kDa anti-sigma factor, DNA (60-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Shi, J, Wen, A, Feng, Y. 登録日 2019-05-27 公開日 2019-08-07 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 Structural basis of sigma appropriation. Nucleic Acids Res., 47, 2019
4LLG	Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex 分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-09 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.7936 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
5UHC	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.796 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UAC	Escherichia coli RNA polymerase and Rifampin complex, wild-type 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Molodtsov, V, Scharf, N.T, Stefan, M.A, Garcia, G.A, Murakami, K.S. 登録日 2016-12-19 公開日 2017-01-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis. Mol. Microbiol., 103, 2017
6KJ6	cryo-EM structure of Escherichia coli Crl transcription activation complex 分子名称: DNA (51-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Xu, J, Zhang, Y. 登録日 2019-07-21 公開日 2020-01-01 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor. Elife, 8, 2019
7N4E	Escherichia coli sigma 70-dependent paused transcription elongation complex 分子名称: 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Molodtsov, V, Su, M, Ebright, R.H. 登録日 2021-06-04 公開日 2022-06-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural and mechanistic basis of sigma-dependent transcriptional pausing. Proc.Natl.Acad.Sci.USA, 119, 2022
7YE2	The cryo-EM structure of C. crescentus GcrA-TACdown 分子名称: Cell cycle regulatory protein GcrA, DNA (90-MER)-non template, DNA (90-MER)-template, ... 著者 Wu, X.X, Zhang, Y. 登録日 2022-07-05 公開日 2023-01-18 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
6UTZ	E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Fresh" crystal soaked with CTP and UTP for 30 minutes) 分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zuo, Y, De, S, Steitz, T.A. 登録日 2019-10-30 公開日 2020-08-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.803 Å) 主引用文献 Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6N62	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-24 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.803 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5W1S	X-ray crystal structure of Escherichia coli RNA polymerase and TraR complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-06-04 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.805 Å) 主引用文献 Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
4G7Z	Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at template-strand position +1 分子名称: 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*(BRU)P*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.815 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012

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