3UN4
| Yeast 20S proteasome in complex with PR-957 (morpholine) | 分子名称: | 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, Proteasome component C1, Proteasome component C11, ... | 著者 | Huber, E, Basler, M, Schwab, R, Heinemeyer, W, Kirk, C, Groettrup, M, Groll, M. | 登録日 | 2011-11-15 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity. Cell(Cambridge,Mass.), 148, 2012
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6P19
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6P1K
| Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2019-05-20 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
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3UNF
| Mouse 20S immunoproteasome in complex with PR-957 | 分子名称: | 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, CHLORIDE ION, IODIDE ION, ... | 著者 | Huber, E, Basler, M, Schwab, R, Heinemeyer, W, Kirk, C, Groettrup, M, Groll, M. | 登録日 | 2011-11-15 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity. Cell(Cambridge,Mass.), 148, 2012
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4NNU
| Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation | 分子名称: | DNA1, DNA2, Transcription factor A, ... | 著者 | Ngo, H.B, Lovely, G.A, Phillips, R, Chan, D.C. | 登録日 | 2013-11-19 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation. Nat Commun, 5, 2014
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8UGP
| In-situ structure of typeA supercomplex in respiratory chain ( local refined map focused on CI iron-sulfur cluster regions ) | 分子名称: | IRON/SULFUR CLUSTER, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6, ... | 著者 | Zheng, W, Zhang, K, Zhu, J. | 登録日 | 2023-10-05 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
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6P59
| Crystal structure of SIVrcm Vif-CBFbeta-ELOB-ELOC complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Core-binding factor subunit beta, Elongin-B, ... | 著者 | Binning, J.M, Chesarino, N.M, Emerman, M, Gross, J.D. | 登録日 | 2019-05-29 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.942214 Å) | 主引用文献 | Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism. Cell Host Microbe, 26, 2019
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6P6W
| Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state | 分子名称: | Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb | 著者 | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A. | 登録日 | 2019-06-04 | 公開日 | 2019-08-14 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178, 2019
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8UGE
| In-situ complex III, state II | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | 著者 | Zheng, W, Zhang, K, Zhu, J. | 登録日 | 2023-10-05 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
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8UGK
| High resolution in-situ structure of complex III in respiratory supercomplex (composite) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | 著者 | Zheng, W, Zhu, J, Zhang, K. | 登録日 | 2023-10-05 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
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4NO6
| yCP in complex with Z-Leu-Leu-Leu-vinylsulfone | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(3S)-5-methyl-1-(methylsulfonyl)hexan-3-yl]-L-leucinamide, Probable proteasome subunit alpha type-7, ... | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | 登録日 | 2013-11-19 | 公開日 | 2014-02-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Angew.Chem.Int.Ed.Engl., 53, 2014
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8U1I
| Crystal structure of SyoA bound to 4-methylsyringol | 分子名称: | 2,6-dimethoxy-4-methylphenol, Cytochrome P450, NITRATE ION, ... | 著者 | Harlington, A.C, Shearwin, K.E, Bell, S.G, Whelan, F. | 登録日 | 2023-09-01 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Structural insights into the S-lignin O-demethylase SyoA To Be Published
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7R3B
| S-adenosylmethionine synthetase from Lactobacillus plantarum complexed with AMPPNP, methionine and SAM | 分子名称: | (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, PHENYLALANINE, ... | 著者 | Shahar, A, Kleiner, D, Bershtein, S, Zarivach, R. | 登録日 | 2022-02-07 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Evolution of homo-oligomerization of methionine S-adenosyltransferases is replete with structure-function constrains. Protein Sci., 31, 2022
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8U09
| Crystal structure of substrate-free SyoA | 分子名称: | ACETATE ION, Cytochrome P450, GLYCEROL, ... | 著者 | Harlington, A.H, Shearwin, K.E, Bell, S.G, Whelan, F. | 登録日 | 2023-08-28 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural insights into the S-lignin O-demethylase SyoA To Be Published
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3T3A
| Crystal structure of H107R mutant of extracellular domain of mouse receptor NKR-P1A | 分子名称: | Killer cell lectin-like receptor subfamily B member 1A, PHOSPHATE ION | 著者 | Kolenko, P, Rozbesky, D, Bezouska, K, Hasek, J, Dohnalek, J. | 登録日 | 2011-07-25 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the H107R variant of the extracellular domain of mouse NKR-P1A at 2.3 A resolution. Acta Crystallogr.,Sect.F, 67, 2011
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8U19
| Crystal structure of SyoA bound to syringol | 分子名称: | 2,6-dimethoxyphenol, Cytochrome P450, MAGNESIUM ION, ... | 著者 | Harlington, A.C, Shearwin, K.E, Bell, S.G, Whelan, F. | 登録日 | 2023-08-31 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Structural insights into the S-lignin O-demethylase SyoA To Be Published
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6PMJ
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6P69
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3T25
| TMAO-grown orthorhombic trypsin (bovine) | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Cahn, J, Venkat, M, Marshall, H, Juers, D. | 登録日 | 2011-07-22 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
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8TRL
| T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lim, J.J, Loh, T.J, Reid, H.H, Rossjohn, J. | 登録日 | 2023-08-09 | 公開日 | 2024-07-31 | 最終更新日 | 2024-09-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nat Commun, 15, 2024
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4NE2
| Pantothenamide-bound Pantothenate Kinase from Klebsiella pneumoniae | 分子名称: | (R)-N-(3-((2-(benzo[d][1,3]dioxol-5-yl)ethyl)amino)-3-oxopropyl)-2,4-dihydroxy-3,3-dimethylbutanamide, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Hughes, S.J, Antoshchenko, T, Kim, K.P, Smil, D, Park, H.W. | 登録日 | 2013-10-28 | 公開日 | 2014-02-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural characterization of a new N-substituted pantothenamide bound to pantothenate kinases from Klebsiella pneumoniae and Staphylococcus aureus. Proteins, 82, 2014
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6P3A
| Crystal Structure Analysis of TAF1 Bromodomain | 分子名称: | 4-{[(3R)-1-(but-3-en-1-yl)-3-methyl-4-(oxan-4-yl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-6-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Transcription initiation factor TFIID subunit 1 | 著者 | Seo, H.-S, Dhe-Paganon, S. | 登録日 | 2019-05-23 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Crystal Structure Analysis of TAF1 Bromodomain To Be Published
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7RML
| Neisseria meningitidis Methylenetetrahydrofolate reductase in complex with FAD | 分子名称: | 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Pederick, J.L, Wegener, K.L, Salaemae, W, Bruning, J.B. | 登録日 | 2021-07-27 | 公開日 | 2022-11-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Biochemical and structural characterization of meningococcal methylenetetrahydrofolate reductase. Protein Sci., 32, 2023
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4O1K
| Crystal structures of two tetrameric beta-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora. | 分子名称: | Carbonic anhydrase, ZINC ION | 著者 | Lehneck, R, Neumann, P, Vullo, D, Elleuche, S, Supuran, C.T, Ficner, R, Poggeler, S. | 登録日 | 2013-12-16 | 公開日 | 2014-03-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal structures of two tetrameric beta-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora. Febs J., 281, 2014
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8UPX
| Omicron-S-MERS-RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,SARS-CoV-2 omicron spike with MERS RBD | 著者 | Bu, F, Li, F, Liu, B. | 登録日 | 2023-10-23 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Pan-beta-coronavirus subunit vaccine prevents SARS-CoV-2 Omicron, SARS-CoV, and MERS-CoV challenge. J.Virol., 2024
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