PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3QPO	Structure of PDE10-inhibitor complex 分子名称: 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(pyridin-2-yl)ethoxy]quinazoline, MAGNESIUM ION, SULFATE ION, ... 著者 Pandit, J, Marr, E.S. 登録日 2011-02-14 公開日 2011-06-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia. J.Med.Chem., 54, 2011
3QL2	Crystal Structure of Ribonuclease A Variant A4C/D83E/V118C 分子名称: Ribonuclease pancreatic, SULFATE ION 著者 Arnold, U, Schoepfel, M. 登録日 2011-02-02 公開日 2012-02-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Significant stabilization of ribonuclease A by additive effects Febs J., 279, 2012
3QLN	Crystal structure of ATRX ADD domain in free state 分子名称: Transcriptional regulator ATRX, ZINC ION 著者 Li, H, Patel, D.J. 登録日 2011-02-03 公開日 2011-06-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome Nat.Struct.Mol.Biol., 18, 2011
3QLY	Candida glabrata dihydrofolate reductase complexed with NADPH and 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP115A) 分子名称: 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Strain CBS138 chromosome J complete sequence 著者 Paulsen, J.L, Bendel, S.D, Anderson, A.C. 登録日 2011-02-03 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.519 Å) 主引用文献 Crystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity. Chem.Biol.Drug Des., 78, 2011
3Q5J	Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of 17-DMAP-geldanamycin 分子名称: (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[3-(dimethylamino)propyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, Heat shock protein 83-1 著者 Wernimont, A.K, Tempel, W, Lin, Y.H, Hutchinson, A, MacKenzie, F, Fairlamb, A, Cossar, D, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) 登録日 2010-12-28 公開日 2011-02-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of 17-DMAP-geldanamycin. To be Published
3QQS	Anthranilate phosphoribosyltransferase (TRPD) from Mycobacterium tuberculosis (complex with inhibitor ACS172) 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2,2'-iminodibenzoic acid, Anthranilate phosphoribosyltransferase, ... 著者 Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2011-02-16 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52, 2013
3Q74	Crystal Structure Analysis of the L7A Mutant of the Apo Form of Human Alpha Class Glutathione Transferase 分子名称: Glutathione S-transferase A1 著者 Fanucchi, S, Achilonu, I.A, Khoza, T.N, Fernandes, M.A, Gildenhuys, S, Dirr, H.W. 登録日 2011-01-04 公開日 2011-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal Structure Analysis of the L7A Mutant of the Apo Form of Human Alpha Class Glutathione Transferase To be Published
3Q8E	Crystal structure of Protective Antigen W346F (pH 8.5) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. 登録日 2011-01-06 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q9W	Crystal structure of human CK2 alpha in complex with emodin at pH 8.5 分子名称: 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, Casein kinase II subunit alpha, SULFATE ION 著者 Battistutta, R, Ranchio, A, Papinutto, E. 登録日 2011-01-10 公開日 2012-01-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2 To be Published
3QST	Crystal structure of Trichomonas vaginalis triosephosphate isomerase TVAG_096350 gene (Val-45 variant) 分子名称: SODIUM ION, Triosephosphate isomerase, putative 著者 Lara-Gonzalez, S, Salgado-Lugo, H, Brieba, L.G. 登録日 2011-02-21 公開日 2012-07-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of Trichomonas vaginalis triosephosphate isomerase TVAG_096350 gene to be published
3QAW	Crystal structure of a glutathione-S-transferase from Antarctic clam Laternula elliptica in a complex with glutathione 分子名称: GLUTATHIONE, Rho-class glutathione S-transferase 著者 Park, A.K, Moon, J.H, Chi, Y.M. 登録日 2011-01-12 公開日 2012-02-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of a shellfish specific GST class glutathione S-transferase from antarctic bivalve Laternula elliptica reveals novel active site architecture. Proteins, 81, 2013
3QEH	Crystal structure of human N12-i15, an ADCC and non-neutralizing anti-HIV-1 Env antibody 分子名称: CHLORIDE ION, Fab fragment of human anti-HIV-1 Env antibody N12-i15, heavy chain, ... 著者 Guan, Y, DeVico, A.L, Lewis, G.K, Pazgier, M. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Crystal structure of human N12-i15, an ADCC and non-neutralizing anti-HIV-1 Env antibody To be Published
3QFD	Human Class I MHC HLA-A2 in complex with Mart-1(27-35) nonameric peptide 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2011-01-21 公開日 2011-09-28 最終更新日 2011-12-14 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility: IMPLICATIONS FOR VACCINE DESIGN. J.Biol.Chem., 286, 2011
3QGP	Crystal structure of IsdI in complex with heme and cyanide 分子名称: CYANIDE ION, Heme-degrading monooxygenase isdI, MAGNESIUM ION, ... 著者 Ukpabi, G.N, Murphy, M.E.P. 登録日 2011-01-24 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Heme Ruffling Enables the Catalytic Activity of the Heme Degrading Enzyme IsdI To be Published
3QS9	Crystal structure of a human Flt3 ligand-receptor ternary complex 分子名称: FL cytokine receptor, SL cytokine 著者 Verstraete, K, Savvides, S.N. 登録日 2011-02-20 公開日 2011-03-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (7.8 Å) 主引用文献 Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex. Blood, 118, 2011
3QID	Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase 分子名称: GLYCEROL, MANGANESE (III) ION, RNA dependent RNA polymerase, ... 著者 Kim, K.H, Intekhab, A, Lee, J.H. 登録日 2011-01-27 公開日 2011-12-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase. J.Gen.Virol., 92, 2011
3QUG	Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Gallium-porphyrin 分子名称: GLYCEROL, Iron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING GA, ... 著者 Moriwaki, Y, Caaveiro, J.M.M, Tsumoto, K. 登録日 2011-02-24 公開日 2011-03-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus. Biochemistry, 50, 2011
3QJZ	Crystal structure of PI3K-gamma in complex with benzothiazole 1 分子名称: N-{6-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-benzothiazol-2-yl}acetamide, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION 著者 Whittington, D.A, Tang, J, Yakowec, P. 登録日 2011-01-31 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors. J.Med.Chem., 54, 2011
3QUH	Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Manganese(III)-porphyrin 分子名称: GLYCEROL, Iron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING MN 著者 Moriwaki, Y, Caaveiro, J.M.M, Tsumoto, K. 登録日 2011-02-24 公開日 2011-03-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus. Biochemistry, 50, 2011
3QL9	Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide 分子名称: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3 著者 Xiang, B, Li, H. 登録日 2011-02-02 公開日 2011-06-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (0.93 Å) 主引用文献 ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome Nat.Struct.Mol.Biol., 18, 2011
3QLH	HIV-1 Reverse Transcriptase in Complex with Manicol at the RNase H Active Site and TMC278 (Rilpivirine) at the NNRTI Binding Pocket 分子名称: (2S)-5,7-dihydroxy-9-methyl-2-(prop-1-en-2-yl)-1,2,3,4-tetrahydro-6H-benzo[7]annulen-6-one, 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, ... 著者 Himmel, D.M, Wojtak, K, Bauman, J.D, Arnold, E. 登録日 2011-02-02 公開日 2011-12-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Synthesis, activity, and structural analysis of novel alpha-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H. J.Med.Chem., 54, 2011
3QW1	Crystal structure of the Zn-RIDC1 complex stabilized by BMH crosslinks 分子名称: 1-methylpyrrolidine-2,5-dione, Cytochrome cb562, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Salgado, E.N, Tezcan, F.A. 登録日 2011-02-26 公開日 2011-06-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Templated construction of a zn-selective protein dimerization motif. Inorg.Chem., 50, 2011
3QWE	Crystal structure of the N-terminal domain of the GEM interacting protein 分子名称: GEM-interacting protein, UNKNOWN ATOM OR ION 著者 Guan, X, Tempel, W, Tong, Y, Shen, L, Wang, H, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) 登録日 2011-02-28 公開日 2011-03-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the N-terminal domain of the GEM interacting protein to be published
3QWU	Putative ATP-dependent DNA ligase from Aquifex aeolicus. 分子名称: ADENOSINE, CALCIUM ION, DNA ligase, ... 著者 Osipiuk, J, Quartey, P, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2011-02-28 公開日 2011-03-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Putative ATP-dependent DNA ligase from Aquifex aeolicus. To be Published
3QO1	Monoclinic form of IgG1 Fab fragment (apo form) sharing same Fv as IgA 分子名称: Fab fragment of IMMUNOGLOBULIN G1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN G1 LIGHT CHAIN, GLYCEROL 著者 Trajtenberg, F, Correa, A, Buschiazzo, A. 登録日 2011-02-09 公開日 2012-02-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of a human IgA1 Fab fragment at 1.55 angstrom resolution: potential effect of the constant domains on antigen-affinity modulation Acta Crystallogr.,Sect.D, 69, 2013

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