3Q5J
Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of 17-DMAP-geldanamycin
Summary for 3Q5J
Entry DOI | 10.2210/pdb3q5j/pdb |
Related | 3H80 3Q5I 3Q5K 3Q5L |
Descriptor | Heat shock protein 83-1, (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[3-(dimethylamino)propyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate (3 entities in total) |
Functional Keywords | sleeping sickness, leishmania, heat shock protein, structural genomics, structural genomics consortium, sgc, chaperone |
Biological source | Leishmania major |
Total number of polymer chains | 1 |
Total formula weight | 26741.24 |
Authors | Wernimont, A.K.,Tempel, W.,Lin, Y.H.,Hutchinson, A.,MacKenzie, F.,Fairlamb, A.,Cossar, D.,Zhao, Y.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T.,Structural Genomics Consortium (SGC) (deposition date: 2010-12-28, release date: 2011-02-23, Last modification date: 2023-09-13) |
Primary citation | Wernimont, A.K.,Tempel, W.,Lin, Y.H.,Hutchinson, A.,MacKenzie, F.,Fairlamb, A.,Cossar, D.,Zhao, Y.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Ferguson, M.A.J.,Hui, R.,Pizarro, J.C.,Hills, T. Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of 17-DMAP-geldanamycin. To be Published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report