PDB: 35415 件ウェブページステータス検索Chemie searchBIRD

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6TQM	Escherichia coli AdhE structure in its compact conformation 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Aldehyde-alcohol dehydrogenase, FE (III) ION 著者 Fronzes, R, Pony, P. 登録日 2019-12-16 公開日 2020-06-03 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation. Nat Commun, 11, 2020
6TTB	Crystal structure of NAD-dependent formate dehydrogenase from Staphylococcus aureus in complex with NAD 分子名称: Formate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Boyko, K.M, Pometun, A.A, Nikolaeva, A.Y, Kargov, I.S, Yurchenko, T.S, Savin, S.S, Popov, V.O, Tishkov, V.I. 登録日 2019-12-26 公開日 2021-01-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of NAD-dependent formate dehydrogenase from Staphylococcus aureus in complex with NAD To Be Published
6HC2	Crystal structure of NuMA/LGN hetero-hexamers 分子名称: G-protein-signaling modulator 2, Nuclear mitotic apparatus protein 1 著者 Pasqualato, S, Culurgioni, S, Foadi, J, Alfieri, A, Mapelli, M. 登録日 2018-08-13 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (4.31 Å) 主引用文献 Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions. Nat Commun, 10, 2019
6HRL	Crystal structure of the Kelch domain of human KLHL17 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Kelch-like protein 17, ... 著者 Chen, Z, Williams, E, Sorrell, F.J, Newman, J.A, Shrestha, L, Burgess-Brown, N, von Delft, F, Arrowsmith, F, Edwards, C.H, Bountra, C, Bullock, A.N. 登録日 2018-09-27 公開日 2018-10-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the Kelch domain of human KLHL17 To Be Published
6GDD	DIHYDROOROTASE FROM AQUIFEX AEOLICUS UNDER 1200 BAR OF HYDROSTATIC PRESSURE 分子名称: Dihydroorotase, SULFATE ION, ZINC ION 著者 Prange, T, Girard, E, Herve, G, Evans, D.R. 登録日 2018-04-23 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Pressure-induced activation of latent dihydroorotase from Aquifex aeolicus as revealed by high pressure protein crystallography. Febs J., 286, 2019
2KLD	Solution Structure of the Calcium Binding Domain of the C-terminal Cytosolic Domain of Polycystin-2 分子名称: Polycystin-2 著者 Kalbitzer, H.R. 登録日 2009-07-01 公開日 2009-07-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR-assignments of a cytosolic domain of the C-terminus of polycystin-2 Biomol.Nmr Assign., 3, 2009
7AYY	Structure of the human 8-oxoguanine DNA Glycosylase hOGG1 in complex with activator TH10785 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, N-glycosylase/DNA lyase, ... 著者 Masuyer, G, Davies, J.R, Stenmark, P. 登録日 2020-11-13 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
7AYZ	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with activator TH10785 分子名称: N-glycosylase/DNA lyase, NICKEL (II) ION, ~{N}-cyclohexyl-2-cyclopropyl-quinazolin-4-amine 著者 Masuyer, G, Davies, J.R, Stenmark, P. 登録日 2020-11-13 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
7AZ0	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with TH12161 分子名称: 2-cyclopropyl-~{N}-(4-iodophenyl)quinazolin-4-amine, N-glycosylase/DNA lyase, NICKEL (II) ION 著者 Davies, J.R, Masuyer, G, Stenmark, P. 登録日 2020-11-13 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
6G3Y	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH5675 分子名称: 4-(4-azanyl-2-oxidanylidene-3~{H}-benzimidazol-1-yl)-~{N}-(4-iodophenyl)piperidine-1-carboxamide, ACETATE ION, N-glycosylase/DNA lyase, ... 著者 Masuyer, G, Helleday, T, Stenmark, P. 登録日 2018-03-26 公開日 2018-11-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation. Science, 362, 2018
6GEQ	Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121A1 in complex with Triazole Pyrazole inhibitor 14a 分子名称: 1-phenyl-3-pyridin-4-yl-~{N}-(pyridin-4-ylmethyl)pyrazole-4-carboxamide, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C.W. 登録日 2018-04-27 公開日 2019-08-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Design and Synthesis of Imidazole and Triazole Pyrazoles asMycobacterium TuberculosisCYP121A1 Inhibitors. Chemistryopen, 8, 2019
2O53	Crystal structure of apo-Aspartoacylase from human brain 分子名称: Aspartoacylase, PHOSPHATE ION, ZINC ION 著者 Le Coq, J, Pavlovsky, A, Sanishvili, R, Viola, R.E. 登録日 2006-12-05 公開日 2007-11-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue. Biochemistry, 47, 2008
6TJV	Structure of the NDH-1MS complex from Thermosynechococcus elongatus 分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, BETA-CAROTENE, ... 著者 Schuller, J.M, Saura, P, Thiemann, J, Schuller, S.K, Gamiz-Hernandez, A.P, Kurisu, G, Nowaczyk, M.M, Kaila, V.R.I. 登録日 2019-11-27 公開日 2020-02-19 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Redox-coupled proton pumping drives carbon concentration in the photosynthetic complex I. Nat Commun, 11, 2020
6TET	The structure of CYP121 in complex with inhibitor L21 分子名称: 1,2-ETHANEDIOL, 1-[(~{E})-3-[4-(4-fluorophenyl)phenyl]prop-2-enyl]imidazole, Mycocyclosin synthase, ... 著者 Adam, S, Koehnke, J. 登録日 2019-11-12 公開日 2021-05-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.49986887 Å) 主引用文献 Structure-Activity Relationship and Mode-Of-Action Studies Highlight 1-(4-Biphenylylmethyl)-1H-imidazole-Derived Small Molecules as Potent CYP121 Inhibitors. Chemmedchem, 16, 2021
6TEV	The structure of CYP121 in complex with inhibitor L44 分子名称: 1,2-ETHANEDIOL, 1-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]imidazole, Mycocyclosin synthase, ... 著者 Adam, S, Koehnke, J. 登録日 2019-11-12 公開日 2021-05-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.70001268 Å) 主引用文献 Structure-Activity Relationship and Mode-Of-Action Studies Highlight 1-(4-Biphenylylmethyl)-1H-imidazole-Derived Small Molecules as Potent CYP121 Inhibitors. Chemmedchem, 16, 2021
6TE7	The structure of CYP121 in complex with inhibitor S2 分子名称: 1,2-ETHANEDIOL, 2-chloranyl-4-[4-[(1~{R})-1-imidazol-1-ylprop-2-enyl]phenyl]phenol, Mycocyclosin synthase, ... 著者 Adam, S, Koehnke, J. 登録日 2019-11-11 公開日 2021-05-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.50001824 Å) 主引用文献 Structure-Activity Relationship and Mode-Of-Action Studies Highlight 1-(4-Biphenylylmethyl)-1H-imidazole-Derived Small Molecules as Potent CYP121 Inhibitors. Chemmedchem, 16, 2021
2KPU	NMR Structure of YbbR family protein Dhaf_0833 (residues 32-118) from Desulfitobacterium hafniense DCB-2: Northeast Structural Genomics Consortium target DhR29B 分子名称: YbbR family protein 著者 Cort, J.R, Ramelot, T.A, Yang, Y, Belote, R.L, Ciccosanti, C, Haleema, J, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) 登録日 2009-10-20 公開日 2009-12-08 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Structures of domains I and IV from YbbR are representative of a widely distributed protein family. Protein Sci., 20, 2011
2O4H	Human brain aspartoacylase complex with intermediate analog (N-phosphonomethyl-L-aspartate) 分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION 著者 Le Coq, J, Pavlovsky, A, Sanishvili, R, Viola, R.E. 登録日 2006-12-04 公開日 2007-11-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue. Biochemistry, 47, 2008
2OHV	Structural Basis for Glutamate Racemase Inhibition 分子名称: (4S)-4-(2-NAPHTHYLMETHYL)-D-GLUTAMIC ACID, Glutamate Racemase 著者 Kim, E.E. 登録日 2007-01-10 公開日 2007-09-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for glutamate racemase inhibition J.Mol.Biol., 372, 2007
6G3X	Native Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 分子名称: N-glycosylase/DNA lyase, NICKEL (II) ION 著者 Masuyer, G, Helleday, T, Stenmark, P. 登録日 2018-03-26 公開日 2018-11-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation. Science, 362, 2018
6TWM	Product bound structure of the Ectoine utilization protein EutE (DoeB) from Ruegeria pomeroyi 分子名称: 2,4-DIAMINOBUTYRIC ACID, ACETATE ION, N-acetyl-L-2,4-diaminobutyric acid deacetylase, ... 著者 Mais, C.-N, Altegoer, F, Bange, G. 登録日 2020-01-13 公開日 2020-05-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex. J.Biol.Chem., 295, 2020
2W3U	formate complex of the Ni-Form of E.coli deformylase 分子名称: FORMIC ACID, NICKEL (II) ION, PEPTIDE DEFORMYLASE 著者 Ngo, Y.H.T, Palm, G.J, Hinrichs, W. 登録日 2008-11-14 公開日 2009-12-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structure of the Ni(II) Complex of Escherichia Coli Peptide Deformylase and Suggestions on Deformylase Activities Depending on Different Metal(II) Centres. J.Biol.Inorg.Chem., 15, 2010
3HWC	Crystal Structure of Chlorophenol 4-Monooxygenase (TftD) of Burkholderia cepacia AC1100 分子名称: Chlorophenol-4-monooxygenase component 2 著者 Ballinger, J.W, Kang, C.H. 登録日 2009-06-17 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:FAD oxidoreductase (TftC) of Burkholderia cepacia AC1100. J.Biol.Chem., 285, 2010
2W1B	The structure of the efflux pump AcrB in complex with bile acid 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACRIFLAVIN RESISTANCE PROTEIN B 著者 Drew, D, Klepsch, M.M, Newstead, S, Flaig, R, De Gier, J.W, Iwata, S, Beis, K. 登録日 2008-10-17 公開日 2008-12-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.85 Å) 主引用文献 The Structure of the Efflux Pump Acrb in Complex with Bile Acid. Mol.Membr.Biol., 25, 2008
6T9X	Crystal structure of formate dehydrogenase FDH2 D222Q/Q223R mutant enzyme from Granulicella mallensis MP5ACTX8 in complex with NADP and Azide. 分子名称: AZIDE ION, Formate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Robescu, M.S, Rubini, R, Filippini, F, Bergantino, B, Cendron, L. 登録日 2019-10-29 公開日 2020-09-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 From the Amelioration of a NADP+-dependent Formate Dehydrogenase to the Discovery of a New Enzyme: Round Trip from Theory to Practice Chemcatchem, 2020

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