4KD5
 
 | | substrate binding domain of putative molybdenum ABC transporter from Clostridium difficile | | 分子名称: | 2-BUTANOL, ABC-type transport system, molybdenum-specific extracellular solute-binding protein, ... | | 著者 | Maltseva, N, Kim, Y, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-04-24 | | 公開日 | 2013-05-08 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4999 Å) | | 主引用文献 | Substrate binding domain of putative molybdenum ABC transporter from Clostridium difficile 630
TO BE PUBLISHED
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3MHG
 | | Dihydroxyacetone phosphate carbanion intermediate in tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes | | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, CALCIUM ION, Tagatose 1,6-diphosphate aldolase 2 | | 著者 | LowKam, C, Liotard, B. | | 登録日 | 2010-04-07 | | 公開日 | 2010-04-28 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structure of a class I tagatose-1,6-bisphosphate aldolase: investigation into an apparent loss of stereospecificity.
J.Biol.Chem., 285, 2010
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4KK1
 | | Crystal Structure of TSC1 core domain from S. pombe | | 分子名称: | Tuberous sclerosis 1 protein homolog | | 著者 | Sun, W, Zhu, Y, Wang, Z.Z, Zhong, Q, Gao, F, Lou, J.Z, Gong, W.M, Xu, W.Q. | | 登録日 | 2013-05-05 | | 公開日 | 2013-07-17 | | 最終更新日 | 2013-07-31 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Crystal structure of the yeast TSC1 core domain and implications for tuberous sclerosis pathological mutations.
Nat Commun, 4, 2013
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4KQ9
 | | Crystal structure of periplasmic ribose ABC transporter from Conexibacter woesei DSM 14684 | | 分子名称: | GLYCEROL, Ribose ABC transporter, substrate binding protein | | 著者 | Nocek, B, Chhor, G, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2013-05-14 | | 公開日 | 2013-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of periplasmic ribose ABC transporter from Conexibacter woesei DSM 14684
To be Published
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8PB1
 | | Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1), obtained after local refinement. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ... | | 著者 | Felix, J, Bloch, Y, Savvides, S.N. | | 登録日 | 2023-06-08 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
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3MT1
 | | Crystal structure of putative carboxynorspermidine decarboxylase protein from Sinorhizobium meliloti | | 分子名称: | Putative carboxynorspermidine decarboxylase protein, SULFATE ION | | 著者 | Chang, C, Xu, X, Cui, H, Chin, S, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-04-29 | | 公開日 | 2010-06-30 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of putative carboxynorspermidine decarboxylase protein from Sinorhizobium meliloti
To be Published
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4JZA
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4KK0
 | | Crystal Structure of TSC1 core domain from S. pombe | | 分子名称: | Tuberous sclerosis 1 protein homolog | | 著者 | Sun, W, Zhu, Y, Wang, Z.Z, Zhong, Q, Gao, F, Lou, J.Z, Gong, W.M, Xu, W.Q. | | 登録日 | 2013-05-05 | | 公開日 | 2013-07-17 | | 最終更新日 | 2013-07-31 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the yeast TSC1 core domain and implications for tuberous sclerosis pathological mutations.
Nat Commun, 4, 2013
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6RV7
 | | Crystal Structure of Glucuronoyl Esterase from Cerrena unicolor inactive S270A variant in complex with the aldouronic acid UXXR | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-Xylitol, ... | | 著者 | Ernst, H.A, Mosbech, C, Langkilde, A, Westh, P, Meyer, A, Agger, J.W, Larsen, S. | | 登録日 | 2019-05-31 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | The structural basis of fungal glucuronoyl esterase activity on natural substrates.
Nat Commun, 11, 2020
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3M0Z
 | | Crystal structure of putative aldolase from Klebsiella pneumoniae. | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, SULFATE ION, ... | | 著者 | Chang, C, Rakowski, E, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-03-03 | | 公開日 | 2010-03-31 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal structure of putative aldolase from Klebsiella pneumoniae.
To be Published
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4K9H
 | | Bace-1 inhibitor complex | | 分子名称: | 1-cyclopentyl-N-[(2S,3R)-3-hydroxy-1-phenyl-4-{[3-(trifluoromethyl)benzyl]amino}butan-2-yl]-6-oxo-5-(2-oxopyrrolidin-1-yl)-1,6-dihydropyridine-3-carboxamide, Beta-secretase 1 | | 著者 | Jordan, S.R. | | 登録日 | 2013-04-19 | | 公開日 | 2013-07-10 | | 最終更新日 | 2013-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Hydroxyethylamine-based inhibitors of BACE1: P1-P3 macrocyclization can improve potency, selectivity, and cell activity.
Bioorg.Med.Chem.Lett., 23, 2013
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7C9I
 | | Human gamma-secretase in complex with small molecule L-685,458 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yang, G, Zhou, R, Guo, X, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2020-06-05 | | 公開日 | 2021-01-27 | | 最終更新日 | 2021-02-03 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of gamma-secretase inhibition and modulation by small molecule drugs.
Cell, 184, 2021
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4KB5
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3M8W
 | | Phosphopentomutase from Bacillus cereus | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, MANGANESE (II) ION, ... | | 著者 | Panosian, T.D, Nannemann, D.P, Watkins, G, Wadzinski, B, Bachmann, B.O, Iverson, T.M. | | 登録日 | 2010-03-19 | | 公開日 | 2010-12-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Bacillus cereus Phosphopentomutase Is an Alkaline Phosphatase Family Member That Exhibits an Altered Entry Point into the Catalytic Cycle.
J.Biol.Chem., 286, 2011
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4K0R
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3MGL
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6RU1
 | | Crystal Structure of Glucuronoyl Esterase from Cerrena unicolor inactive S270A variant in complex with the aldouronic acid Um4X | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ... | | 著者 | Ernst, H.A, Mosbech, C, Langkilde, A, Westh, P, Meyer, A, Agger, J.W, Larsen, S. | | 登録日 | 2019-05-27 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | The structural basis of fungal glucuronoyl esterase activity on natural substrates.
Nat Commun, 11, 2020
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4KL7
 | | Crystal structure of the catalytic domain of RpfB from Mycobacterium tuberculosis | | 分子名称: | Resuscitation-promoting factor RpfB, SULFATE ION | | 著者 | Squeglia, F, Romano, M, Ruggiero, A, Berisio, R. | | 登録日 | 2013-05-07 | | 公開日 | 2013-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Carbohydrate Recognition by RpfB from Mycobacterium tuberculosis Unveiled by Crystallographic and Molecular Dynamics Analyses.
Biophys.J., 104, 2013
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4KKY
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4KMQ
 | | 1.9 Angstrom resolution crystal structure of uncharacterized protein lmo2446 from Listeria monocytogenes EGD-e | | 分子名称: | Lmo2446 protein, MAGNESIUM ION | | 著者 | Halavaty, A.S, Minasov, G, Filippova, E.V, Dubrovska, I, Winsor, J, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-05-08 | | 公開日 | 2013-05-29 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure to function of an alpha-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis.
Nat Microbiol, 2, 2016
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4KO9
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3MGG
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7CN9
 | | Cryo-EM structure of SARS-CoV-2 Spike ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ho, M, Chang, Y, Wang, C, Wu, Y, Huang, H, Chen, T, Lo, J.M, Chen, X, Ma, C. | | 登録日 | 2020-07-30 | | 公開日 | 2020-08-26 | | 最終更新日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2.
Cell Rep, 32, 2020
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7CQ6
 | | Structure of the human CLCN7-OSTM1 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, H(+)/Cl(-) exchange transporter 7, ... | | 著者 | Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L. | | 登録日 | 2020-08-08 | | 公開日 | 2020-11-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of the human CLCN7-OSTM1 complex
To Be Published
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4K0D
 | | Periplasmic sensor domain of sensor histidine kinase, Adeh_2942 | | 分子名称: | ACETATE ION, CHLORIDE ION, Periplasmic sensor hybrid histidine kinase, ... | | 著者 | Pokkuluri, P.R, Mack, J.C, Bearden, J, Rakowski, E, Schiffer, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2013-04-03 | | 公開日 | 2013-06-12 | | 最終更新日 | 2015-04-15 | | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | | 主引用文献 | Analysis of periplasmic sensor domains from Anaeromyxobacter dehalogenans 2CP-C: structure of one sensor domain from a histidine kinase and another from a chemotaxis protein.
Microbiologyopen, 2, 2013
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