PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

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6OTM	Carbonic Anhydrase IX mimic complexed with ureic benzene sulfonamide MB10-586B 分子名称: 4-hydroxy-3-({[2-(pyridin-2-yl)ethyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Kota, A, McKenna, R. 登録日 2019-05-03 公開日 2020-05-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.307 Å) 主引用文献 Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB9-561B To Be Published
6OTP	Carbonic Anhydrase II complexed with ureic benzene sulfonamide MB10-586B 分子名称: 4-hydroxy-3-({[2-(pyridin-2-yl)ethyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Kota, A, McKenna, R. 登録日 2019-05-03 公開日 2020-05-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.466 Å) 主引用文献 Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB9-561B To Be Published
6LF0	Structure of FEM1C 分子名称: Protein fem-1 homolog C, SULFATE ION 著者 Chen, X, Liao, S, Xu, C. 登録日 2019-11-27 公開日 2020-10-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
6OUI	Carbonic Anhydrase IX mimic complexed with benzene sulfonamide MB11-710A 分子名称: 3-{[(4-hydroxybutyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Kota, A, McKenna, R. 登録日 2019-05-04 公開日 2020-05-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.528 Å) 主引用文献 Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB11-710A To Be Published
6RRI	Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 2,3,5,6-tetrakis(fluoranyl)benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-05-18 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.097 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
6OTO	Carbonic Anhydrase II complexed with ureic benzene sulfonamide MB9-561B 分子名称: 4-hydroxy-3-({[(pyridin-4-yl)methyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Kota, A, McKenna, R. 登録日 2019-05-03 公開日 2020-05-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.496 Å) 主引用文献 Carbonic Anhydrase II complexed with ureido benzene sulfonamide MB9-561B To Be Published
6RTM	Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1-[(dimethylamino)methyl]-2-naphthol at 2 hour of soaking 分子名称: 1-methylidenenaphthalen-2-one, FLAVIN-ADENINE DINUCLEOTIDE, POTASSIUM ION, ... 著者 Angelucci, F, Silvestri, I, Fata, F, Williams, D.L. 登録日 2019-05-24 公開日 2020-01-08 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Ectopic suicide inhibition of thioredoxin glutathione reductase. Free Radic Biol Med, 147, 2020
3K2F	Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma 分子名称: (2S)-2,3-bis(nitrooxy)propyl ethyl[(4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]carbamate, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Temperini, C, Cecchi, A. 登録日 2009-09-30 公開日 2009-11-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma Bioorg.Med.Chem.Lett., 19, 2009
6ENW	X-ray structure of Auoxo4-encapsulated horse spleen apoferritin 分子名称: CADMIUM ION, CHLORIDE ION, Ferritin light chain, ... 著者 Ferraro, G, Merlino, A. 登録日 2017-10-06 公開日 2017-12-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Ferritin nanocages loaded with gold ions induce oxidative stress and apoptosis in MCF-7 human breast cancer cells. Dalton Trans, 46, 2017
6EOF	Crystal structure of AMPylated GRP78 in ADP state 分子名称: 78 kDa glucose-regulated protein, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Yan, Y, Preissler, S, Read, R.J, Ron, D. 登録日 2017-10-09 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
6S1N	Human polymerase delta holoenzyme Conformer 2 分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... 著者 Lancey, C, Hamdan, S.M, De Biasio, A. 登録日 2019-06-19 公開日 2019-12-25 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.86 Å) 主引用文献 Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
6E8X	CA IX mimic Complexed with Steroidal Sulfamate Compound STX 140 分子名称: (13alpha,17alpha)-2-methoxyestra-1,3,5,7,9,11-hexaene-3,17-diyl disulfamate, Carbonic anhydrase 2, ZINC ION 著者 Andring, J.T, Mckenna, R. 登録日 2018-07-31 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 3,17 beta-Bis-sulfamoyloxy-2-methoxyestra-1,3,5(10)-triene and Nonsteroidal Sulfamate Derivatives Inhibit Carbonic Anhydrase IX: Structure-Activity Optimization for Isoform Selectivity. J. Med. Chem., 62, 2019
6RJJ	Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 2,3-bis(fluoranyl)benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-04-27 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.056 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
8TKZ	Structure of fission yeast Duf89 protein bound to Co2+ and PO4 分子名称: CHLORIDE ION, COBALT (II) ION, DI(HYDROXYETHYL)ETHER, ... 著者 Jacewicz, A, Sanchez, A.M, Shuman, S. 登録日 2023-07-26 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structure of fission yeast Duf89 protein bound to Co2+ and PO4 To Be Published
3KA4	Frog M-ferritin with cobalt 分子名称: CHLORIDE ION, COBALT (II) ION, Ferritin, ... 著者 Tosha, T, Ng, H.L, Theil, E, Alber, T, Bhattasali, O. 登録日 2009-10-18 公開日 2010-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Moving Metal Ions through Ferritin-Protein Nanocages from Three-Fold Pores to Catalytic Sites. J.Am.Chem.Soc., 132, 2010
6S4U	LXRbeta ligand binding domain in comlpex with small molecule inhibitors 分子名称: 6-[4-[[3-oxidanyl-1,1-bis(oxidanylidene)-5-phenyl-2-propan-2-yl-3~{H}-1,2-thiazol-4-yl]amino]butyl]pyridine-2-sulfonamide, Oxysterols receptor LXR-beta 著者 Sandmark, J, Jansson, A. 登録日 2019-06-28 公開日 2019-11-27 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands. Commun Biol, 2, 2019
6S5B	Non-square conformation of KtrA R16K mutant ring with bound ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A 著者 Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H. 登録日 2019-07-01 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.052 Å) 主引用文献 Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019
6S7R	Non-square conformations of KtrA R16A mutant rings with bound ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A 著者 Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H. 登録日 2019-07-05 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.73 Å) 主引用文献 Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019
6RQI	Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 3-fluorobenzenesulfonamide, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-05-15 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
7JYV	Crystal Structure of HLA A*2402 in complex with YFSPIRVTF, an 9-mer influenza epitope 分子名称: Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ... 著者 Gras, S, Nguyen, A.T, Szeto, C, Rossjohn, J. 登録日 2020-09-01 公開日 2021-04-14 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nat Commun, 12, 2021
7JYU	Crystal Structure of HLA-A*2402 in complex with IYFSPIRVTF, an 10-mer epitope from Influenza B virus 分子名称: Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ... 著者 Nguyen, A.T, Szeto, C, Rossjohn, J, Gras, S. 登録日 2020-09-01 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nat Commun, 12, 2021
7JYW	Crystal Structure of HLA A*2402 in complex with TYQWIIRNW, an 9-mer influenza epitope 分子名称: Beta-2-microglobulin, CALCIUM ION, MHC class I antigen, ... 著者 Gras, S, Nguyen, A.T, Szeto, C, Rossjohn, J. 登録日 2020-09-01 公開日 2021-04-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nat Commun, 12, 2021
7JYX	Crystal Structure of HLA A*2402 in complex with TYQWIIRNWET, an 11-mer epitope from Influenza 分子名称: Beta-2-microglobulin, MHC class I antigen, PB2 peptide from Influenza, ... 著者 Gras, S, Nguyen, A.T, Szeto, C, Rossjohn, J. 登録日 2020-09-01 公開日 2021-04-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nat Commun, 12, 2021
6E8P	CA IX mimic Complexed with Steroidal Sulfamate Compound STX 49 分子名称: (14beta,17beta)-estra-1(10),2,4,6,8-pentaene-3,17-diyl disulfamate, Carbonic anhydrase 2, ZINC ION 著者 Andring, J.T, Mckenna, R. 登録日 2018-07-30 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 3,17 beta-Bis-sulfamoyloxy-2-methoxyestra-1,3,5(10)-triene and Nonsteroidal Sulfamate Derivatives Inhibit Carbonic Anhydrase IX: Structure-Activity Optimization for Isoform Selectivity. J. Med. Chem., 62, 2019
6P2T	BshB from Bacillus subtilis complexed with citrate 分子名称: CITRIC ACID, N-acetyl-alpha-D-glucosaminyl L-malate deacetylase 1, SODIUM ION, ... 著者 Cook, P.D, Meloche, C.E. 登録日 2019-05-22 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.853 Å) 主引用文献 X-ray crystallographic structure of BshB, the zinc-dependent deacetylase involved in bacillithiol biosynthesis. Protein Sci., 29, 2020

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